Examinando por Materia "Delayed Graft Function"

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    ÍtemAcceso abierto
    Effectiveness of tacrolimus compared to cyclosporine in reducing delayed graft function in adult kidney transplant recipients
    (Universidad Privada Norbert Wiener, 2018-08-26) Fernandez Palacios, Fatima Tatjana; Orco Contreras, Ruth Magally; Matta Solis, Hernán Hugo
    Systematic observational and retrospective quantitative review, subjected to critical selection, using the Grade evaluation system to identify the degree of evidence, found in the following databases: Pubmed, Wolters Kluwer, Insights, Wiley Online Library, Researchgate; They are studies, 10% are meta-analyses, 40% are experimental and 50% are cohorts, with a high quality of evidence in 50% of studies carried out in China, Germany, Brazil, Turkey, Australia, London, Brazil, Austria, Mexico respectively. Results: 80% of the evidence found indicates that tacrolimus is more effective compared to cyclosporine to reduce delayed graft function in adult kidney recipients of transplanted organs. In 10% of the evidence found, no statistically significant differences were found in the efficacy of both tacrolimus and cyclosporine, both of which had the effect of acute graft rejection in adult kidney transplant recipients of both treatments. 10% of the evidence found indicates that there is insufficient scientific evidence to determine the effectiveness of tacrolimus compared to cyclosporine. Conclusion: it is concluded that tacrolimus is more effective compared to cyclosporine in reducing delayed graft function in adult kidney transplant recipients.
  • Miniatura
    ÍtemAcceso abierto
    Efficacy of hypothermic perfusion machine compared to cold storage in reducing the risk of developing delayed graft function in cadaveric donor renal transplantation
    (Universidad Privada Norbert Wiener, 2020-02-01) Orozco Espinoza, Katherine Thalia; Salvador Ramirez, Karla Stefany; Arevalo Marcos, Rodolfo Amado
    Objective: Systematize the evidence on the hypothermic perfusion machine compared to cold storage to reduce the risk of developing delayed graft function in deceased donor kidney transplantation. Material and Methods: Retrospective and observational systematic review subject to critical reading and using the GRADE system as an evaluation tool to identify the quality of scientific evidence published in the following information sources Scielo, Elsevier, PubMed and Epistemonikos. Of the 10 articles reviewed systematically, 100% of high quality as described below: 90% of high quality as described below: 50% (n= 5/10) are meta-analyses, 20% (n= 2/ 10) is a systematic review and 20% (n= 2/10) are randomized controlled trials of moderate quality. 10% (n= 1/10) is a cohort study and They belong to the countries of China (20%), Australia (10%), England (10%), Spain (10%), Canada (10%), Brazil (10%), Belgium (10%), Netherlands (10%). %) and the United States (10%). Results: 100% (n=10/10) indicate that the hypothermic perfusion machine is more effective than cold storage in reducing the risk of developing delayed graft function in kidney transplant from a deceased donor. Conclusion: The hypothermic perfusion machine is more effective than cold storage in reducing the risk of developing delayed graft function in deceased donor kidney transplantation.