Examinando por Materia "Drug Contamination"
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Publicación Acceso abierto La adulteración y calidad desinfectante del alcohol expendido en oficinas farmacéuticas y otros establecimientos comerciales, Lima – Cercado, setiembre 2020(Universidad Privada Norbert Wiener, 2022-05-19) Vargas Espinal, Maribel Juvenalda; Laureano Peña, Haydee Sonia; Llahuilla Quea, José AntonioThe methodology used consisted of a random probabilistic sampling of 32 samples of 96° ethyl alcohols in 1 L bottles sold in pharmaceutical offices (sample B: 15 samples from drugstores and pharmacies) and other commercial establishments (sample A: 17 samples from small shops, shopping centers, and street vendors). Methanol was identified using the chromotropic acid reaction method. A sensory evaluation was conducted according to Peruvian Technical Standard 211.007:2014. The determination of physicochemical parameters (pH, alcoholic strength, and density) was performed according to the United States Pharmacopeia and Peruvian Technical Standard 319.229:2014. Disinfectant effectiveness was determined in accordance with the UNE-EN 1040 method for chemical antiseptics and disinfectants. The results identified positive methanol results in 13.3% of the B samples and 11.76% of the A samples. The alcoholic strength showed results lower than 96°, with an average of 93 in the B samples and 79 in the A samples. Additionally, the disinfectant effectiveness in the sample with the lowest alcoholic strength for group B showed a bactericidal activity greater than 99.99% at 30 seconds of contact against the microorganisms S. aureus and P. aeruginosa, while for group A, no bactericidal activity was observed.Publicación Acceso abierto Cuantificación de partículas extrañas en las mezclas de nutrición parenteral sistema binario en la Central de Elaboración de Medical Nutrición. Lima, 2016(Universidad Privada Norbert Wiener, 2017) Quispe Quispe, Julia Patricia; Salazar Quispe, Josué; Salazar Tuanama, Rita HaydeeThe objective of this research, titled "Quantification of Foreign Particles in Binary System Parenteral Nutrition Admixtures at the Medical Nutrición Compounding Center, Lima, 2016," was to determine the quantification of foreign particles in binary system parenteral nutrition (PN) admixtures at the Medical Nutrición compounding center in Lima in 2016. The study was observational, descriptive, prospective, and cross-sectional. A data registration form was used. The method employed for the determination of the number and size of foreign particles was the Microscopic Particle Count Test (Method 2). Results: The average quantity of foreign particles was 0.695 particles per mL for particles >10 µm, and 0.235 particles per mL for particles >25 µm. None of the samples (0.0%) exceeded the established limits. Conclusion: The product complies with the parameters established by USP 39 Chapter 788 related to the number and size of particles in injectables.Publicación Acceso abierto Participación y farmacontaminación en los pobladores del distrito de San Isidro, Lima - 2024(Universidad Privada Norbert Wiener, 2024-09-04) Misaico Ruiz, Derek; Oyarce Alvarado, ElmerThe disposal of expired or unused medications, commonly originating in the home, usually ends up being flushed down the toilet, sink, or in a trash can with regular garbage. However, since it is a toxic waste, it would not be acceptable for it to have the same fate as regular garbage because it could cause soil and water contamination. Currently, this improper disposal of medications is causing great concern about the damage it could cause to the environment and public health.
