Examinando por Materia "Fitoquímicos"

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Acceso abierto
Critical review: Protective effect of vitamins c, d, e and selenium in thyroid cancer
(Universidad Privada Norbert Wiener, 2021-03-16) Uribe Salas, Arturo Alejandro; Bohórquez Medina, Andrea Lisbet
Globally, thyroid cancer ranks sixth in incidence for 2018, occurring in 3.7% of the population. Likewise, it is located in ninth place in relation to the appearance of new cases, and the increase in them has been observed constantly in the last forty years. Although thyroid cancer is not the most common cancer, it is one of the most diagnosed among endocrine cancers. Because cancer is characterized by an increase in oxidative stress and the formation of free radicals, the possibility has been seen that antioxidant micronutrients may play an important role in the prevention and management of thyroid cancer. It has been shown that the intake or supplementation of vitamin D can generate a favorable change seen from a thyroid cancer prevention perspective. The objective was to find in the scientific literature an association of vitamins C, D and E and selenium with the risk of thyroid cancer or to find a protective effect of vitamins C, D and E and selenium in the treatment of thyroid cancer. Using the NUBE methodology, scientific literature on the relationship of vitamin C, vitamin D, vitamin E and selenium in the risk and treatment of thyroid cancer was integrated from systematic reviews and clinical trials. This research guides health professionals to know a possibility or finding of the nutritional interventions available to be applied for the prevention and nutritional treatment of thyroid cancer.
Acceso abierto
Effect on the proliferation of cancer cells by the consumption of phytochemicals from walnuts in patients with cancer
(Universidad Privada Norbert Wiener, 2022-05-18) Ramos Villanueva, Juselly Mercedes; Bohórquez Medina, Andrea Lisbet
Cancer, as a pathology, is not considered unique, as it encompasses more than 200 different types of cancer and is one of the leading causes of death worldwide. By 2020, it was estimated that there would be an increase to 19.3 million new cases and 10 million deaths from cancer. In Peru, the cancers with the highest number of new cases were prostate, breast, stomach, colon, and cervical cancer, with prostate, cervical, and stomach cancers having the highest mortality rates. Although cancer is considered a genetically-based disease, nutrition plays an increasingly important role. Reviews cite bioactive compounds in food that serve functions in the body and can promote good health, such as the phytochemicals in walnuts, which are beneficial for coronary diseases, rheumatism, diabetes mellitus, obesity, and certain types of cancer. There is a correlation between the regular consumption of walnuts and a decrease in cancer incidence. Therefore, a critical review was conducted with the aim of determining the effects of bioactive components in walnuts on the proliferation of cancer cells in different types of cancer. A methodology based on the principles of evidence-based nutrition was used; a systematic search was conducted in PubMed and Science Direct for publications from the last 5 years to answer the research question. After selecting the studies, the CASPE tool was applied to determine the level of recommendation and evidence. Finally, the article with the highest level of evidence was selected, and a critical comment was developed to provide a collection of practical recommendations for nutritionists and healthcare professionals.
Acceso abierto
Revisión crítica: efecto de la ingesta de fitoquímicos sobre la proliferación de células cancerosas en el tejido mamario
(Universidad Privada Norbert Wiener, 2025-05-14) Yaicurima Ramirez, Iris Maritza; Bohórquez Medina, Andrea Lisbet
La ingesta de fitoquímicos puede mejorar los resultados después del cáncer de mama. Su ingesta es relevante en una dieta saludable a través de hábitos alimentarios, cada vez hay más pruebas de estudios in vitro, in vivo y de biomarcadores humanos que respaldan los efectos anticancerígenos de varios de los fitoquímicos de las plantas. Por ese motivo, la presente investigación secundaria, titulada "Revisión Crítica: Efecto de la ingesta de fitoquímicos sobre la proliferación de células cancerosas en el tejido mamario", tuvo como objetivo identificar el efecto de la ingesta de fitoquímicos sobre la proliferación de células cancerosas en el tejido mamario. La pregunta clínica fue: ¿La ingesta de fitoquímicos tiene un efecto sobre la proliferación de células cancerosas en el tejido mamario? Se empleó la metodología de “Nutrición Basada en Evidencia (NuBE)”. Se realizó la revisión de artículos en las bases de datos: SCOPUS, PUBMED, COCHRANE Y SCIENCEDIRECT; de los cuales fueron seleccionadas 10 revisiones sistemáticas y metaanálisis, las que fueron evaluadas de forma critica mediante la herramienta CASPe. Finalmente, se eligió la Revisión Sistemática y metaanálisis titulada "Fitonutrientes y cáncer de mama", evidenciando un nivel AI y un Grado de Recomendación FUERTE, según la experticia de la investigadora. Al realizar el comentario crítico se puede concluir que los fitoquímicos de la soja, la enterolactona y el té verde demostraron tener un efecto significativo en la reducción del riesgo sobre el cáncer de mama.