Examinando por Materia "Hepatitis B Vaccine"

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    Immune response to the hepatitis B vaccine in patients treated with hemodialysis and dialysis
    (Universidad Privada Norbert Wiener, 2019-04-07) Suarez Calle, Erika Jaqueline; Avila Vargas Machuca, Jeannette Giselle
    Objective: To systematically analyze the available evidence from studies carried out on the immune response to the hepatitis B vaccine when applied to patients treated with hemodialysis. Materials and Methods: Systematic review of 10 articles of high and moderate quality of evidence according to the GRADE evaluation; found in the following databases: PubMed, Elsevier, Springer Link, JAMA network, ASCO. Results: The analysis of 10 scientific articles with full text was carried out, 05 were retrospective and prospective cohort investigations, 01 meta-analysis and 4 clinical trials. 100% of the articles concluded that the immune response is affected when the hepatitis B vaccine is applied to patients treated with hemodialysis. Conclusion: From the systematic study of the 10 scientific articles, it is evident that 8 of the 10 articles (80%) patients treated with hemodialysis and dialysis achieved an immune response greater than 50% to those who received three and four doses of 40mcg of hepatitis B vaccine; and in 2 of the 10 articles (20%), patients treated with hemodialysis and dialysis achieved an immune response of less than 50%, with the percentage being higher when the four-dose scheme was applied. Resulting in 100% effectiveness in the 10 scientific articles.