Examinando por Materia "Hypertonic Solutions"

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Acceso abierto
Effectiveness of the use of mannitol versus hypertonic solution in neurocritical patients with brain injuries
(Universidad Privada Norbert Wiener, 2017-08-05) Maza Chavez, Evelin Flor; Pachas Cordova, Wendy Cecilia; Pérez Siguas, Rosa Eva
Objective: To analyze and synthesize the evidence on the efficacy of mannitol versus hypertonic solution in neurocritical patients with brain injuries. Materials and methods: This systematic review is observational and retrospective. Searches were conducted across various databases, but finally, articles with full text were selected and critically reviewed, using the GRADE assessment to identify the level of evidence. Results: Of the 10 articles reviewed, 9/10 articles show that the use of hypertonic solution has greater efficacy in managing neurocritical patients with brain injuries, accounting for 90%. Among these, 10% of the articles do not consider the data sufficient to define the efficacy between these treatments. Conclusions: The systematic review demonstrated that hypertonic solution is more effective in neurocritical patients with brain injuries, showing better cerebral perfusion and increasing the survival rate of the neurocritical patient.
Acceso abierto
Efficacy of Nebulization with 3% Hypertonic Solution Versus 0.9% Saline Solution in Children Under 2 Years of Age With Bronchiolitis
(Universidad Privada Norbert Wiener, 1905-07-09) Marcelo Avalos, Mónica Jesús; Maylle Antaurco, Teodosia Carmen; Gamarra Bustillos, Carlos
Objective: To evaluate the effectiveness of the use of 3% hypertonic solution versus 0.9% saline solution in children under 2 years of age with bronchiolitis who receive nebulizations. Materials and methods: The type of study is a systematic review, and this is of literature published during the period 2011-2016, 10 articles were selected, subjected to a critical reading, using the GRADE SYSTEM to identify the degree of evidence and strength recommendation of each article. 70% of the articles show that there is effectiveness of a 3% hypertonic solution, since it reduces hospital stay, admission rate, shorter oxygen therapy time, lower economic cost and fewer side effects compared to saline solution 0.9 %. Conclusions: Our study demonstrates a firm evidence base for the use of 3% hypertonic solution in bronchiolitis in children under two years of age, being more effective compared to 0.9% saline solution.