Examinando por Materia "Hypoxia-Ischemia, Brain"

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Acceso abierto
Effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic-ischemic encephalopathy
(Universidad Privada Norbert Wiener, 2018-12-16) Asencios Nieto, Yeny Elizabeth; Cabrera Andía, Macedonia; Uturunco Vera, Milagros Lizbeth
MATERIAL AND METHOD: The systematic review of the 10 articles on the effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic ischemic encephalopathy were found in the following databases: Cochrane, Scielo and Pubmed. Of the 10 articles reviewed, 60% (6/10) correspond to the methodological design of systematic reviews and/or meta-analysis, 30% (3/10) are randomized clinical trials and 10% (1/10) are studies cross. All of them were analyzed according to the Grade scale to determine their strength and quality of evidence. RESULTS: 100% of the reviewed articles are conclusive, these are supported by 6 systematic reviews, 3 randomized clinical trials and 1 cross-sectional study, all of which suggest the use of induced therapeutic hypothermia is the best alternative for the hospital management of newborns. with hypoxic ischemic encephalopathy. However, some of these authors suggest conducting further follow-up studies to verify the effectiveness of this intervention in the long term. CONCLUSIONS: Of the 10 articles reviewed, 100% (10/10) show the effectiveness of induced therapeutic hypothermia in neuroprotection in newborns with hypoxic ischemic encephalopathy, because it reduces neurological damage, sequelae and a decrease in the mortality rate. .
Acceso abierto
Effectiveness of therapeutic cooling in the decrease of complications in the neonate with ischemical hypxical- encephalopathy
(Universidad Privada Norbert Wiener, 2019-08-04) Aparcana Palacios, Ada María; Matta Solis, Hernán Hugo
Objective: To systematize the effectiveness of therapeutic cooling in reducing complications in hypoxic ischemic encephalopathy. Material and Methods: A quantitative observational and retrospective systematic review, carried out with an elective evaluation using the Grade method to identify the level of evidence, located in the various data sources: PubMed, Scielo, Cochrane Library and Elsevier. Of the 10 articles systematically reviewed, 40% (n = 4/10) are systematic reviews, 10% (n = 1/10) are retrospective studies and 10% (n = 1/10) are randomized trials, 10% (n = 1/10) case-control studies, 10% (n = 1/10) prospective multicenter cohort trial, 10% (n = 1/10) longitudinal non-experimental study, 20% (n = 2/10) are observational cohort studies. According to the effects obtained in the systematic review carried out in the current study, they derive from the countries of Spain (20%), followed by the United States (20%), Australia (10%), France (10%), London (10%), Uruguay (10%), Colombia (10%), Canada (10%) Results: Consequently, of the findings found, 100% (n = 10/10) indicate that therapeutic cooling is effective as a treatment to reduce complications in newborns with hypoxic ischemic encephalopathy. Conclusion: Therapeutic cooling is effective as a treatment to reduce complications in newborns with hypoxic ischemic encephalopathy.
Acceso abierto
Efficacy of probiotics in the prevention of the most frequent infections in the preterm newborn.
(Universidad Privada Norbert Wiener, 2018-08-12) Haro Shapiama, Gianina; Guevara López, Lorena Astrick; Calsin Pacompia, Wilmer
90% of the 10 scientific studies demonstrate the effectiveness of the use of probiotics in preventing the most common infections in premature newborns (early sepsis and enterocolitis), while also improving oral tolerance, intestinal maturation, and increasing the weight of preterm neonates. 10% of the studies show that there is no significant difference, highlighting the need for further studies to address the combination of probiotic strains, dosage, and duration to avoid erroneous conclusions, especially in very low birth weight neonates.