Examinando por Materia "Immune System"

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Acceso abierto
Effectiveness of oropharyngeal colostrum intake in strengthening the immune system in newborns
(Universidad Privada Norbert Wiener, 2018-11-25) Rodriguez Pari, Erika Melissa; Soto Vera, María Eugenia; Millones Gómez, Segundo Germán
Objective: Analyze the evidence on the effectiveness of ingesting colostrum via the oropharynx to strengthen the immune system in the newborn. Material and Methods: The design of a systematic review. The population is made up of 39 articles that were reviewed, of which only 10 scientific articles were chosen as a sample, their instrument was research based on databases: Pubmed, Cochrane, Database. Results: Of the total articles analyzed, 40% (n= 4/10) are randomized controlled trials (RCTs), 30% (3/10) are cohort studies, 20% (n= 2/10) are reviews. systematic, and 10% (n= 1/10) is quasi-experimental, according to the quality of the evidence it was found to be high in 60% and moderate in 40%. According to the strong recommendation strength 60% and weak 40%. According to the country where the investigations were carried out, they correspond to the United States 70%, China 10%, South Korea 10% and Spain 10% respectively. According to the review, it is evident that 80% (n = 8/10) of the articles indicate the effectiveness of ingesting colostrum through the oropharyngeal route to strengthen the immune system in the newborn and 20% (n = 2/10) of the articles indicate non-effectiveness. Conclusion: 8 of 10 reviewed articles indicate the effectiveness of ingesting colostrum through the oropharyngeal route to strengthen the immune system in the newborn. 2 of 10 articles indicate that ingesting colostrum through the oropharyngeal route is not effective in strengthening the immune system in the newborn; since some authors point out that larger studies are needed to describe the benefit of colostrum.
Acceso abierto
Effectiveness of oropharyngeal colostrum intake to strengthen the immune system in the premature newborn
(Universidad Privada Norbert Wiener, 2021-03-14) Valdivia Rojas, Eli Jhasmin; Chumbe Meza, Keyla Pamela; Fernández Rengifo, Werther Fernando
Objective: To systematically analyze the available evidence from studies carried out on the effectiveness of oropharyngeal colostrum ingestion to strengthen the immune system in premature newborns. Material and Method: The systemic review design. The population is made up of 20 articles that were reviewed, of which only 10 scientific articles were chosen as a sample, which had research based on databases as an instrument: Pubmed, Cochrane, BVS. To evaluate the articles, the GRADE system was used, which evaluated the quality of evidence and the strength of recommendation. Results: Of the total number of articles analyzed, 70% (n=7/10) of the articles point out the effectiveness of ingesting oropharyngeal colostrum to strengthen the immune system in premature newborns. Conclusion: 7 of 10 articles conclude that ingesting colostrum via the oropharyngeal route is effective in strengthening the immune system in premature newborns since colostrum contains a large amount of immunoglobulin A and lactoferrin which act as a defense protein, improving its profile. immunological and thus demonstrate the importance of early nutrition with colostrum. 3 of 10 articles conclude that new studies are needed to describe the benefits of colostrum, which did not detect statistically significant differences in both groups and could not prove the conjecture that the administration of colostrum reduces the incidence of sepsis and increases IgA levels. in the premature newborn.