Examinando por Materia "Immunogenicity, Vaccine"

Mostrando 1 - 1 de 1

Acceso abierto
Effectiveness of rotavirus vaccine immunogenicity in relation to breastfeeding
(Universidad Privada Norbert Wiener, 2018-08-26) Benavides Bolivar, María del Carmen; Carlos Acuña, Milagros Esther; Rivera Lozada De Bonilla, Oriana
Objective: Systematize the evidence on the effectiveness of the immunogenicity of the rotavirus vaccine against breastfeeding. Methodology/Methods: Observational and retrospective systematic review, the articles were subjected to a critical reading to identify their level of evidence. Results: 10 articles were chosen, 40% (04) correspond to South Africa, 20% (02) Europe and Asia, 10% (01) Pakistan, India, Mexico, respectively. 10 randomized studies were included. 90% of articles state that the immunogenicity of the rotavirus vaccine can be affected or decreased by factors such as breastfeeding and malnutrition. The extent of the effect depends on the maternal titer of anti-rotavirus antibodies in breast milk, as with higher titers found in less developed areas. With 10% of the reviews, in which it was recommended to withhold breastfeeding for up to 1 hour before and after administration, there was no immune response from the infants. Conclusions: It was evident that the decrease in immunogenicity of the rotavirus vaccine could be attributed to several factors, not only breastfeeding; but due to childhood or maternal malnutrition, environmental enteropathy, interference from maternal antibodies and the presence of other intestinal infections; Breastfeeding should still continue.