Examinando por Materia "Interferon-gamma"

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    Interferon gamma and hematological biomarkers in patients with latent tuberculosis infection care at a health center in Lima - Peru 2020
    (Universidad Privada Norbert Wiener, 2023-12-03) Quispe Huamaní, Ross Mery Lady; Astete Medrano, Delia Jessica
    Currently, a quarter of the world's population is infected with the Koch bacillus but shows no symptoms. This condition is called latent tuberculosis infection. Objective: To determine the relationship between gamma interferon and hematological biomarkers in patients with latent tuberculosis infection treated at a health center in Lima, Peru, in 2020. Method and Design: Observational, cross-sectional, and correlational study. Results from 133 patients who underwent the QFT-Plus test between January and February 2020 and their hemograms were collected. Additionally, 20 patients with active TB were included as controls. Results: Hemograms of patients with ILTB (33.8%) were compared, finding a statistically significant finding with a p-value < 0.036 in the lymphocytes of male patients with ILTB. Conclusions: Gamma interferon is only related to the absolute lymphocyte count parameter in male patients. Further research is needed to identify other hematological indicators that help differentiate the status or progression of ILTB patients.