Examinando por Materia "Liver Neoplasms"

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Critical review: Influence of flavonoid consumption on liver cancer
(Universidad Privada Norbert Wiener, 2021-02-03) Pasco Rosado, Patricia del Carmen; Lozada Urbano, Michelle Fatima
Liver cancer is the sixth type of cancer with the highest mortality rate, with hepatocellular carcinoma being the most common, representing 90% of all cases, which originates in cells called hepatocytes. The present secondary research entitled critical review: Influence of flavonoid consumption on liver cancer, aimed to determine the influence of flavonoid consumption on liver cancer. The clinical question was: How does the consumption of flavonoids influence patients with liver conditions and liver cancer? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in Pubmed, Scielo, Wiley, Science Direct, Google scholar and Taylor & Francis, finding 52 articles, 23 being selected that have been evaluated by the CASPE critical reading tool, finally selecting the article titled Autophagy: a potential therapeutic target of polyphenols in hepatocellular carcinoma, which has a level of evidence A II and a strong degree of recommendation, according to the researcher's expertise. The critical commentary allowed us to conclude that flavonoids have antioxidant, anti-inflammatory, carcinogen inactivating, antiproliferative, cell cycle arrest inducers, apoptotic, antiangiogenic, autophagy modulators and multiple drug reversal effects, in addition, they help prevent and treat several types of cancer including hepatocellular carcinoma.