Examinando por Materia "Microbioma Gastrointestinal"

Mostrando 1 - 8 de 8

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Critical review: effect of exercise on gut microbiota in people with metabolic diseases
(Universidad Privada Norbert Wiener, 2024-02-14) García León, Melba Luisa; Bohórquez Medina, Andrea Lisbet
Metabolic syndrome (MS) is considered a group of metabolic diseases as a risk factor, and it has increased in recent years worldwide, becoming a public health problem that increases the risk of developing various diseases such as diabetes and cardiovascular issues by 2 to 6 times. This research aimed to create a scientific critical commentary based on a literature review on the established problem to understand its consequences. The Evidence-Based Nutrition (EBN) methodology was used. After searching for articles, 13 were selected to be evaluated using the CASPE tool for critical reading. The selected article titled ‘Effect of exercise on the intestinal microbiota in individuals with metabolic diseases’ was chosen, with a high level of evidence and recommendation grade AI-Strong. The critical commentary concluded that there is significant evidence to suggest that regular moderate-intensity exercise affects intestinal metabolism and microbiota in individuals with insulin resistance. It is suggested to conduct further research, as the present study found a negative correlation between intestinal FAU and whole-body insulin sensitivity.
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Critical review: effects of low protein diet and alpha supplementation Keto analogues in the improvement of the intestinal microbiota and the reduction of uremic toxins in patients with kidney disease
(Universidad Privada Norbert Wiener, 2024-07-04) Quispe Galvez, Jean Carlos; Dávila Córdova, Jennifer Estefania
This secondary research titled Critical Review: Effects of Low-Protein Diets and Alpha-Ketoanalog Supplementation in Reducing Uremic Toxins in Patients with Chronic Kidney Disease aimed to identify articles that answered the clinical question: Does nutritional intervention with low-protein diets and alpha-ketoanalog supplementation reduce uremic toxin levels in adults with CKD with or without dialysis? The Evidence-Based Nutrition (EBN) methodology was used. Information was gathered from PUBMED, SCIENCE DIRECT, SCOPUS, and SCIELO, and evaluated using the CASPE tool. The randomized clinical trial titled “Ketoanalogs' Effects on Intestinal Microbiota Modulation and Uremic Toxins Serum Levels in Chronic Kidney Disease (Medika2 Study)” was selected, as it has an AI level of evidence and a strong recommendation grade, according to the researcher's expertise. The critical review concluded that nutritional therapy with low-protein diets and alpha-ketoanalog supplementation helps reduce a specific uremic toxin in CKD patients and thereby reduce gastrointestinal discomfort.
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Critical Review: Effects of prebiotics, probiotics and/or synbiotics to improve the intestinal microbiota and the levels of nitrogenous products in patients with CKD.
(Universidad Privada Norbert Wiener, 2022-05-05) Chumpitazi Alcantara, Cynthia Leonor; Dávila Córdova, Jennifer Estefania
Nutritional intervention in patients with CKD to slow the progression of kidney disease has been little studied. However, today more studies are being conducted to generate additional options for patient benefit. The present secondary research, titled Critical Review: Effects of Prebiotics, Probiotics, and Synbiotics to Improve Gut Microbiota and Nitrogenous Product Levels in Patients with CKD, aimed to identify articles that answer the clinical question: Will nutritional intervention with prebiotics, probiotics, and synbiotics improve gut microbiota and nitrogenous product levels in adults with CKD, with or without dialysis? The methodology used was Evidence-Based Nutrition (EBN). Information was searched in PUBMED, MEDLINE, SCIELO, using the CASPE critical reading tool. The final selection was the Randomized Clinical Trial titled Synbiotics Relieving Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial, which has an A2 level of evidence and a Strong Recommendation Grade, according to the researcher's expertise. The critical commentary concluded that synbiotic therapy helps reduce a specific uremic toxin in patients with CKD and helps regulate gut microbiota.
Acceso abierto
Critical review: influence of diet on gut microbiota composition in patients with chronic non-communicable diseases under 75 years of age
(Universidad Privada Norbert Wiener, 2020-12-22) Eléspuru Zuta, Oriana; Palma Gutiérrez, Edgardo Jhoffire
Modulation of the intestinal microbiota through diet can have a beneficial effect on the development of Chronic Non-Communicable Diseases (NCCD). The present secondary research titled as a critical review: Influence of diet on the composition of the intestinal microbiota in patients with chronic non-communicable diseases under 75 years of age, aimed to analyze the influence of the type of diet on the composition of the intestinal microbiota of patients with NCD under 75 years of age. The clinical question was: What is the type of diet that improves the composition of the intestinal microbiota in patients under 75 years of age who suffer from chronic non-communicable diseases? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, NML, Cochrane Library, finding 36 articles, 10 were selected that have been evaluated by the CASPE critical reading tool, finally selecting the Randomized Controlled Clinical Trial entitled Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake, which has a level of evidence I and Grade of Recommendation Strong, according to the researcher's expertise. The critical commentary allowed us to conclude that the Mediterranean diet positively influences the composition of the intestinal microbiota in patients with NCD under 75 years of age and can be considered within the nutritional intervention in these people.
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Critical Review: Influence of intestinal microbiota alteration on the development of colorectal cancer.
(Universidad Privada Norbert Wiener, 2020-12-10) Oscco Huayta, Villiam Anibal; Bohórquez Medina, Andrea Lisbet
According to the World Health Organization (WHO), cancer is a public health problem. Among them, colorectal cancer has the highest incidence. The present investigation, Influence of the alteration of the intestinal microbiota on the development of colorectal cancer, was developed as a critical review. Objective: Evaluate the scientific literature through a critical reading of it, using the Critical Appraisal Skills Program Spanish (CASPE) tool in published studies. The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, SCIELO, SCOPUS, SCIENCE DIRECT, REDALYC, DIALNET, LILACS, finding 87 articles, selecting 29 that were evaluated by the CASPE critical reading tool, selecting the Systematic Review entitled Preclinical and clinical relevance of probiotics and synbiotics in colorectal carcinogenesis: a systematic review, which has a level of evidence AI and Grade of Recommendation Strong, according to the researcher's expertise. The critical commentary concludes that intestinal dysbiosis influences colorectal carcinogenesis. However, more studies are necessary to identify the characteristics of the eubiosis profile. It is important that new prophylactic, diagnostic and therapeutic strategies be carried out based on research into the intestinal microbiota.
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Effectiveness of hand hygiene with alcohol-based solution compared to other solutions in reducing bacterial flora in healthcare workers
(Universidad Privada Norbert Wiener, 2018-08-26) Asto Soria, Sully Miriam; Rivera Lozada De Bonilla, Oriana
Objective: Systematize the effectiveness of hand hygiene with alcohol-based solution compared to other solutions for reducing the bacterial flora of health personnel. Material and Methods: Quantitative systematic review. Population 52 articles, sample 10 scientific articles, databases: Scielo, Pubmed, Elsevier. 100% quantitative study. According to the results obtained, 10% of the methodological design are systematic reviews, 70% experimental and 20% quasi-experimental; quality of evidence high in 10%, weak 70% and moderate 20%. Strong recommendation strength 10% and weak 90%. Results: According to the review of 100% (n=10/10) of the scientific articles, it was evident that 40% (n=4/10) indicate the effectiveness of hand hygiene with alcohol-based solution compared to other solutions. to reduce the bacterial flora in health personnel. 60% (n=6/10) say they are discordant. Conclusion: 4 articles point out the effectiveness of hand hygiene with alcohol-based solution compared to other solutions for reducing bacterial flora in health personnel; and, 6 articles point out that it is discordant.
Acceso abierto
Revisión crítica: alteración del microbioma intestinal de los pacientes sometidos a una cirugía bariátrica
(Universidad Privada Norbert Wiener, 2025-05-14) Ramírez Quintana, Cynthia Esmeralda; Ponce Castillo, Melissa
La formación de la microbiota intestinal humana, influenciada por factores ambientales y dietéticos, destaca la diversidad microbiana en el intestino y su estabilidad a lo largo de la vida. Desequilibrio, conocido como disbiosis, que se asocia, por citar algunas, con la obesidad y las adaptaciones postquirúrgicas; alteración en su riqueza que sugiere que estas cirugías pueden influir en la diversidad microbiana. De esta manera, la presente revisión crítica, titulada: “Alteración del microbioma intestinal de los pacientes sometidos a una cirugía bariátrica”, tiene el objetivo, fundamental, de analizar la influencia de estas cirugías en la microbiota intestinal y las modificaciones metabólicas posteriores. Se realiza la búsqueda bibliográfica en: PubMed, Scopus, Web of Science y otros; para seleccionar entre 40 artículos – que presentan como palabras clave “Cirugía bariátrica” y “microbioma intestinal” – los 10 que por su calidad metodológica – ensayos clínicos aleatorizados, revisiones sistemáticas y metaanálisis – respondan las preguntas que se consignan en las planillas de evaluación CASPe, según el diseño de investigación clínica. Considerando la revisión sistemática: “Gut Microbiota Profile in Adults Undergoing Bariatric Surgery: A Systematic Review” para el desarrollo del comentario crítico, tomando en cuenta – a criterio del evaluador – el nivel de evidencia “AII” y grado de recomendación “Fuerte”.
Acceso abierto
Revisión crítica: la suplementación con probióticos en pacientes adultos con obesidad reduce parámetros antropométricos
(Universidad Privada Norbert Wiener, 2025-05-22) Barros Gamboa, Jani Baket; Ponce Castillo, Melissa
De acuerdo con la OMS los casos prevalentes de sobrepeso en adultos con 39% y el 13% con obesidad, seguirán aumentando como resultado de los hábitos dietéticos actuales y los estilos de vida sedentarios y una de las estrategias es el estudio del microbioma intestinal, ya que contribuye a la salud humana, donde el vínculo entre la disbiosis y la obesidad ya es conocido. El presente trabajo de investigación secundario con el título revisión crítica: La suplementación con probióticos en pacientes adultos con obesidad reduce parámetros antropométricos, cuya finalidad es determinar los beneficios de suplementar con probióticos en adultos con obesidad. Se realizó la búsqueda con metodología Nutrición Basada en Evidencia (NuBE). La recopilación de datos se realizó en PUBMED, SCIENCE DIRECT, SCIELO, se encontró 41 artículos, pero solo 10 fueron evaluados por la herramienta para lectura crítica CASPE, seleccionando así el Ensayo Clínico Aleatorizado titulado “A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being” con un nivel de evidencia I y Grado de Recomendación Fuerte, de acuerdo con el investigador. En resumen, la intervención que consistió en la administración de probióticos durante un periodo de 6 meses con una dosis de 50 mil millones de ufc/dia logró una reducción considerable en el peso corporal, el índice de masa corporal, el perímetro de la cintura y la relación cintura/estatura mostrando una mayor pérdida de peso en los participantes que presentaban sobrepeso.