Examinando por Materia "Microbiota"

Mostrando 1 - 5 de 5

Acceso abierto
Characteristics of the vaginal microbiota in asymptomatic sex workers who attend the Hospital Nacional Hipolito Unanue 2020
(Universidad Privada Norbert Wiener, 2022-04-07) Sanchez García, Stefany Ingrid; García Vásquez, Carlos Hugo
This research aimed to determine the characteristics of the vaginal microbiota in asymptomatic sex workers attending the National Hospital Hipólito Unanue in Lima in 2020. Our vaginal microbiota helps maintain a healthy vaginal environment, with our lactobacilli preventing the proliferation of pathogenic microorganisms. Proper maintenance of vaginal health reduces the risk of contracting diseases, particularly in our at-risk group of asymptomatic sex workers. This study is non-experimental with a quantitative, observational, prospective, cross-sectional descriptive design and a simple design. The study sample consisted of 60 asymptomatic sex workers. The study of vaginal microbiota characteristics revealed the protective capacity of the vaginal microbiota against external agents in our group of asymptomatic sex workers attending the National Hospital Hipólito Unanue in Lima. On average, 46.7% of asymptomatic sex workers tested positive for altered microbiota, including sexually transmitted diseases. It was concluded that the determination of characteristics in the studied asymptomatic sex workers regarding vaginal microbiota showed 45% positivity for diagnoses of vaginosis and vaginitis.
Acceso abierto
Critical Review: Effects of Omega-3 on the Human Microbiota of At-Risk Adults metabolic
(Universidad Privada Norbert Wiener, 2022-02-15) Talledo Olaya, Silvia María; Dávila Córdova, Jennifer Estefania
The clinical question was: - What is the effect of omega 3 fatty acids on the modulation of the microbiota in adults over 18 years of age with any metabolic disease? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, , SCIELO, HINDAWI, , finding 15 articles, 10 being selected that have been evaluated by the CASPE critical reading tool, finally selecting the Randomized Clinical Trial titled “Diets naturally rich in polyphenols and/or or long-chain n-3 polyunsaturated fatty acids differently affect microbiota composition in high-cardiometabolic-risk individuals”, which has a level of evidence I and Grade of Recommendation I, according to the expertise of the researcher. The critical commentary allowed us to conclude that diets naturally rich in polyphenols or long-chain n-3 polyunsaturated fatty acids can modulate the intestinal microbiota and these changes are related to an improvement in the cardiometabolic risk profile.
Acceso abierto
Effect of the use of probiotics in the management of stress and depression in adults
(Universidad Privada Norbert Wiener, 2022-04-28) Uriarte Sánchez, Edward Josehp; Bohórquez Medina, Andrea Lisbet
Probiotics are live microorganisms that provide health benefits. Depression is a very common pathology that could cause emotional as well as physical problems. Recent research has shown a significant bidirectional communication called the gut-brain axis, as well as a relationship between the alteration of the enteric microbiome and psychiatric disorders, which would allow for further studies and the proposal of alternative therapies. The clinical question was: What is the effect of using probiotics in managing stress and depression in adults? The information search was carried out in PUBMED, SCOPUS, SCIENCE DIRECT, and EMBASE, finding 150 articles, of which 21 were selected and evaluated by the CASPE critical reading tool, selecting the Randomized Clinical Trial: “Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota”, which has a level of evidence I and Grade of Recommendation I, according to the researcher's expertise. The critical commentary concluded that the use of probiotics to alleviate depressive symptoms is promising, mainly due to their potential anti-inflammatory effect, but additional double-blind randomized clinical trials and more rigorous studies are needed to support such conclusions.
Acceso abierto
Effectiveness of high-level disinfection of semi-critical medical materials to reduce microbial load
(Universidad Privada Norbert Wiener, 2018-11-25) Humán Flores, Pamela; Rivera Lozada De Bonilla, Oriana
Objective: Systematize the evidence on the effectiveness of high-level disinfection in semi-critical materials to reduce the microbial load. Methodology: systematic descriptive review, to collect the articles those that present full text have been taken and those that were selected were subjected to a critical reading where the GRADE evaluation is used to verify the degree of evidence. Results: 10 articles have been definitively selected, we found that 40% (04) correspond to Brazil, 30% (3) correspond to the United States, 20% (2) correspond to Peru and 10% (1) correspond to Argentina. Where 40% (n=04/10) of these state, they show that high-level disinfection in semi-critical materials is not effective and recommended for this type of medical materials as long as it is not done and a correct process is not followed. due to lack of knowledge or commitment on the part of the working staff; also for not knowing how to use the correct DAN following the technical specifications recommended by the manufacturer, 20% (n=02/10) of these mention that the DAN is effective, 20% (n=02/10) mention that The personnel who are going to use the semi-critical materials must have prior training for the good management of the DAN, 10% (n=01/10) refer and emphasize that the use of the DAN in materials is necessary. semi-critical and 10% (n=01/10) do not report data due to lack of evidence. Conclusions: Based on the scientific articles reviewed, it is concluded that DAN is effective as long as the cleaning and disinfection steps are correctly followed, follow the manufacturer's recommendations, establish protocols in health institutions and have knowledge of DAN good practices.
Acceso abierto
Safe disinfection processes in the sterilization center
(Universidad Privada Norbert Wiener, 2017) Pupuche Villavicencio, María Danesse; Quiroz Pedemonte, Luz Antonia; Gómez Gonzales, Walter Edgar
Objective: To establish safe disinfection processes in the sterilization center. Materials and Methods: Systematic reviews are an observational and retrospective study design that synthesizes the results of multiple primary studies. They are a core component of evidence-based nursing due to their rigorous methodology, identifying relevant studies to answer specific clinical practice questions. Results: In the final selection, 9 articles were chosen. We found that 55.5% (5) were from Brazil, 22.2% (2) were from Peru, and 11.1% (1) were from Colombia. A systematic review from Brazil constituted 11.1%. Cross-sectional studies were from Bogotá, Peru, and Brazil, while experimental studies came from Japan. Conclusions: The cleaning and disinfection process of endoscopes was not effective. The high-level disinfectant (2% glutaraldehyde) was ineffective after the tenth day of activation. High-level disinfection procedures were not optimally performed, with 6.7% of cultures showing positive results for various species of Pseudomonas. The luminometer is an instrument that allows the objective evaluation of quality control in disinfection processes in operating rooms.