Examinando por Materia "Monitoreo de Drogas"

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Acceso abierto
Farmacovigilancia activa del producto farmacéutico Betriderm crema en usuarios de la botica Avi Pharma S.A.C., Lima 2023
(Universidad Privada Norbert Wiener, 2023-11-20) Carrasco Arias, Dana Patricia; Castillo Soto, Pedro Félix
Active pharmacovigilance is one of the methods used to assess information on the safety profile of medicines in relation to the characteristics of their consumers. The objective of this study was to establish the frequency of suspected adverse reactions in users of the pharmaceutical product Betriderm Cream, through an observational, prospective, analytical, and cross-sectional study, conducted in accordance with ethical and clinical guidelines. Sociodemographic characteristics revealed a mean age of 41.9 years (SD 15.2), mean weight of 64.4 kg (SD 12.4), and mean height of 159.0 cm (SD 9.4), with 63.1% being female. Medication use was mainly based on pharmaceutical recommendation (97.9%) and only 2.1% on self-medication, with 95.7% reporting three applications per day, predominantly for 1–3 days (71.9%). Participants reported healthy habits, such as fruit and vegetable consumption at least five days per week (55.6%), but also negative habits, including alcohol and cigarette use in 88.8%. Concomitant medications included naproxen (14.4%), ibuprofen (12.9%), omeprazole (8.6%), valsartan (7.2%), celecoxib (7.2%), paracetamol (7.2%), among others. The prevalence of suspected adverse reactions was 6.47%, corresponding to pruritus. It is concluded that the objectives were achieved, and the frequency observed corresponds to the category defined as very frequent manifestation.
Acceso abierto
Sospechas de reacciones adversas de antihipertensivos en usuarios de la botica Avi Pharma SAC, La Victoria – Lima 2023
(Universidad Privada Norbert Wiener, 2024-05-25) Cajo Zamora, Carlos Alfredo; Yovera Chávez, Ronald Javier; Collantes Llacza, Adela Marlene
Spontaneous reporting is one of the most widely used methods to evaluate information on the safety profile of medicines in relation to the characteristics of their consumers. The objective of this study was to establish the incidence of suspected adverse reactions in users of antihypertensive pharmaceutical products, applying an observational, prospective, analytical, cross-sectional study method. Sociodemographic characteristics were obtained from a sample of 90 consumers in a pharmaceutical establishment, with an average age of 38.9 years, an average weight of 65.3 kg, and predominantly male participants (67.78%). Medication use was mainly based on pharmaceutical recommendation (82.22%), followed by medical prescription (13.33%) and self-medication (4.45%). The most demanded antihypertensives were Captopril 25 mg tablets, Enalapril 10 mg tablets, and Losartan 50 mg capsules. Among concomitant medications, paracetamol, azithromycin, cetirizine, atorvastatin, and acetylcysteine were noted, while hypercholesterolemia (5.6%) stood out among concurrent conditions. An incidence of suspected adverse reactions of 12.0% was identified in 25 consumers of Enalapril and 6.0% in 50 consumers of Captopril, corresponding to expected reactions described in the technical data sheets of the pharmaceutical products.