Examinando por Materia "Neoplasia"

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    Immunohistochemistry in primary sarcoma of the breast, a clinical case report at the Ramiro Prialé Prialé National Hospital, 2021
    (Universidad Privada Norbert Wiener, 2022-11-20) Gutiérrez Maraví, Katherine Denisse; Ascarza Gallegos, Justo Angelo
    A case is presented of a 44-year-old female patient who attended the pathology department for the review of slides and blocks (histological sections) resulting from a right breast tumorectomy performed in a private institution, with a diagnosis of malignant phyllodes tumor of the breast. The corresponding histotechnological procedure was conducted with slide review, new sections of the embedded sample for Hematoxylin-Eosin staining, and immunohistochemical analysis using specific antibodies for cellular antigens to rule out the presumptive diagnosis and the pathological suspicion of primary breast sarcoma, which was found to be significant. The immunohistochemical markers used were EGFR (+), Total Cytokeratin (+ weak focal), P63 (+ weak focal), Ki67 (+ > 40%), Her-2 Neu (-), Estrogen Receptor (-), Progesterone Receptor (-), Vimentin (+ diffuse), Alpha-Actin (+), S-100 (-), CD34 (+ in vessels). Based on the behavior of each marker, the final and definitive diagnosis was primary breast sarcoma.