Examinando por Materia "Neutrophils"

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Acceso abierto
Índice neutrófilo linfocito y la amputación en pacientes con pie diabético, Hospital Nacional Daniel Alcides Carrión, 2023
(Universidad Privada Norbert Wiener, 2025-02-23) Manrique Quispe, Lucrecia Isabel; Huamán Cárdenas, Víctor Raúl
Los problemas del pie diabético son multifactoriales destacando a la neuropatía diabética que implica el daño a los nervios debido a niveles crónicamente elevados de glucosa, reduce la sensibilidad en los pies, lo que permite que lesiones menores pasen desapercibidas y se infecten, disminuye el flujo sanguíneo, impidiendo la correcta cicatrización de las heridas, las infecciones recurrentes agravan estas lesiones, llevando a la gangrena y, en muchos casos, a la necesidad de amputación. Por otro lado, investigaciones realizadas en diferentes países han demostrado que un INL elevado se asocia con un mayor riesgo de infección, sepsis y amputación en pacientes con pie diabético.
Acceso abierto
Índice neutrófilo/linfocito y procalcitonina en pacientes con sepsis del Hospital Nacional Guillermo Almenara Irigoyen, Lima-2023
(Universidad Privada Norbert Wiener, 2025-02-09) Pillco Quispe, Fray Richard; Huamán Cárdenas, Víctor Raúl
El proyecto de investigación llevado a cabo, tuvo por objetivo “Determinar la relación entre los niveles del índice neutrófilo/linfocito y los niveles de procalcitonina en pacientes hospitalizados con sepsis en el Hospital Nacional Guillermo Almenara Irigoyen, Lima 2023”. El método de investigación utilizado, fue hipotético deductivo; con un enfoque cuantitativo y nivel correlacional. Además, el diseño utilizado fue el no experimental. La población de estudio estuvo constituida por 120 historias clínicas de pacientes con diagnóstico de sepsis, para la muestra se consideró 91 historias clínicas.
Acceso abierto
Lymphocyte indices associated with complicated appendicitis in adults in a hospital, 2021 - 2023
(Universidad Privada Norbert Wiener, 2024-08-23) Rodríguez Loloc, Kricel; Chucas Ascencio, Luis Alberto
Introduction: The need to identify accessible, quick, and low-cost markers to recognize complications in acute appendicitis leads to the study of various indices in requested blood tests. Objective: To determine the association between leukocyte indices and complicated appendicitis in adults treated at the National Hospital Edgardo Rebagliati Martins during 2021-2023. Materials and Methods: An observational analytical case-control study was conducted. The population consisted of all adult patients over 18 years old treated for acute appendicitis at the Hospital Edgardo Rebagliati Martins from 2021-2023. A sample of 171 patients was included, divided into 57 cases and 114 controls. Complicated appendicitis was the variable 2, and neutrophil, monocyte, and platelet indices were the variable 1. Data collection was performed from clinical records. Descriptive and inferential statistics were applied with a significance level of p<0.05, and the Odds Ratio (OR) was calculated in both crude and adjusted forms. Results: Of the 171 patients with acute appendicitis, the mean age was 49.7 years (SD 19.1), and 50.29% (n=86) were male. 82.46% (n=47) had an elevated neutrophil/lymphocyte ratio, 54.39% (n=31) had a low monocyte/lymphocyte ratio, and 82.46% (n=47) had an elevated platelet/lymphocyte ratio. In multivariate analysis, an association was reported for the elevated neutrophil/lymphocyte ratio (ORa: 3.5, CI: 1.52-8.05, p=0.003). Conclusions: The elevated neutrophil/lymphocyte ratio is associated with complicated appendicitis in adults.
Acceso abierto
Relationship of the neutrophil index - lymphocytes and serum ferritin levels in covid19 positive patients attended at the semedic medical center, cerca de lima, may 2020 - february 2021
(Universidad Privada Norbert Wiener, 2023-05-28) Clemente Domínguez, Yahaira Edelmira; Huamán Cárdenas, Victor Raul
Objective: To determine the relationship between the neutrophil-lymphocyte index and serum ferritin levels in COVID-19 positive patients attended at the SEMEDIC medical center, from May 2020 to February 2021. Materials and methods: A descriptive, correlational, observational (non-experimental) study was conducted with 43 patients, using non-probabilistic convenience sampling. The participants had a positive antigen test result for SARS-CoV-2, a hemogram report, and serum ferritin measurement. A data collection form was used, and the data were analyzed using SPSS version 21 and Excel 2019, with descriptive tables and bar graphs. Results: A moderate correlation was found between serum ferritin levels and the neutrophil-lymphocyte index in COVID-19 positive patients attended at SEMEDIC. The average age was 53 years, with 58% male and 42% female. Differences in hemogram values were observed. Neutrophilia and lymphopenia were noted. The average ferritin level was 449 ng/ml, and the neutrophil-lymphocyte index was 2.4. Conclusion: A moderate correlation exists between serum ferritin levels and the neutrophil-lymphocyte index in COVID-19 positive patients attended at SEMEDIC (p=0.002); Spearman's Rho = 0.468.