Examinando por Materia "Pastas dentales remineralizantes"

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    Antimicrobial effect of remineralizing toothpastes against streptococcus mutans – In Vitro study, Lima 2020.
    (Universidad Privada Norbert Wiener, 2020-12-28) Lazaro Diego, Miriam Luz; Céspedes Porras, Jacqueline
    The objective of this study was to evaluate the antimicrobial effect of two remineralizing toothpaste formulations compared to a fluoride toothpaste against the ATTCC 25175 strain of Streptococcus mutans through microbiological tests. An in vitro experimental design was used to observe the antimicrobial effect of three toothpaste formulations: Group 1 with a nanocomplex of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), Group 2 with Hydroxyapatite, and Group 3 with Fluoride. The inhibition halos were measured using the disk diffusion method (Kirby-Bauer method) on agar plates previously inoculated with the bacterial strain at 24 and 48 hours. Twenty samples were analyzed per group, and the data were recorded in a previously validated data collection form. Results: The two remineralizing toothpaste formulations, Group 1 with CPP-ACP and Group 2 with Hydroxyapatite, showed antimicrobial effects against the ATTCC 25175 strain of Streptococcus mutans at 24 hours, with mean inhibition halos of 12.60 and 11.65, respectively. At 48 hours, antimicrobial effects were observed in all three groups, with mean inhibition halos of 12.80 for Group 1, 12.0 for Group 2, and 10.20 for Group 3. A significant difference was found between the two measurements for all groups (p=0.000, p<0.05). Conclusion: All three toothpaste formulations evaluated exhibited antimicrobial effects against the ATTCC 25175 strain of Streptococcus mutans at 48 hours, with the remineralizing pastes showing slightly superior effects.