Examinando por Materia "Pediatric medications"

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Evaluation of the Degree of pH and Concentration of Sugars contained in infant syrups used by Pediatric Dentists in Lima, 2021
(Universidad Privada Norbert Wiener, 2021-09-09) Ortiz Alvarado, Cinthia Cristina; Arauzo Sinchez, Carlos Javier
Oral pediatric medications often contain sugar and exhibit varying levels of acidity, both of which can increase the risk of dental caries in patients with chronic use of these medications. Objective: To determine the pH level and sugar concentration in the most commonly used pediatric syrups prescribed by pediatric dentists. Materials and Methods: This observational and descriptive study analyzed six pediatric syrups (commercial and generic) available at the National Institute of Child Health (NSN), selected by convenience sampling. Sugar concentration analysis was performed using a Thermo Scientific Ultimate 3000 HPLC chromatograph (Germening, Germany). pH levels were measured with a pH meter (electrochemical sensor). Both analyses were conducted in two certified laboratories. Data were organized and represented through tables and charts using Microsoft Office Excel. Results: Antibiotics had slightly acidic pH values (6.36 and 5.34), analgesics (4.30 and 4.23) and NSAIDs (4.82 and 4.25) were moderately acidic. Amoxicillin had the pH closest to neutrality (6.36), whereas Panadol was the most acidic (4.23). Regarding individual sugar concentrations, sucrose showed the highest concentration among sugars, except in Panadol and Ibuprofen, which had values below 0.70 g/100g. Total sugar concentrations were higher in antibiotics (70.77 and 78.6), whereas Panadol and Ibuprofen had similarly low total sugar values (0.7). Conclusions: The pediatric oral syrups studied exhibited mild to moderate acidity. Additionally, antibiotics showed the highest total sugar concentration, with sucrose being the predominant individual sugar.