Examinando por Materia "Phosphotransferases (Phosphate Group Acceptor)"

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    Comparative efficacy and safety of phosphate binders in hyperphosphatemic patients with chronic kidney disease.
    (Universidad Privada Norbert Wiener, 2022-05-30) Zavaleta Gavidia, Rosa Haydee; León Cáceres, Johanna del Carmen
    Phosphorus binders reduce the absorption of phosphorus obtained from the diet in the gastrointestinal tract. Critical review entitled: The use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with chronic kidney disease and on hemodialysis, the objective was to prepare the professional critical commentary, according to the clinical studies related to the subject, with the clinical question: Does the use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with Chronic Kidney Disease and on HD?, the method based on evidence from NUBE was used. The search for information was carried out in PUBMED, SCIELO, SCIENCE DIRECT, finding 344 articles, of which 10 articles were selected, evaluated by the critical reading tool CASPE, finally, a Meta-analysis entitled comparative efficacy and safety of phosphorus binders in patients with hyperphosphatemia with chronic kidney disease was selected, with level of evidence AII and Strong Recall Grade; Based on the researcher's experience, critical commentary determined that iron-based phosphate binding agents were the preferred agents in terms of both efficacy and safety.