Examinando por Materia "Plant Oils"

Mostrando 1 - 4 de 4

Acceso abierto
Aceite vegetal como sustituto del xilol en la acción desparafinante en coloraciones histotecnológicas rutinarias. Lima 2021
(Universidad Privada Norbert Wiener, 2023-05-21) Arias Corrales, Carlos Eduardo; Ascarza Gallegos, Justo Angelo
A través de los años el xileno conocido comercialmente como xilol, se ha convertido en el aclarante más utilizado en los procedimientos histotecnológicos, en la desparafinización de las secciones histológicas para sus coloraciones respectivas. Pero los efectos tóxicos de este reactivo, va a causar diversas enfermedades en el organismo de los profesionales que trabajan en los laboratorios de histotecnología, como por ejemplo en la piel produce irritación, eritema y sequedad, en el sistema respiratorio produce dificultades para respirar. Por estas razones en la búsqueda de sustitutos que sean menos tóxicos para la salud de los profesionales y el medio ambiente se presenta el siguiente proyecto de investigación, utilizando el aceite vegetal como desparafinante y así poder reemplazar al xilol en estos procesos
Acceso abierto
Diseño y formulación de una línea dermocosmética a base del aceite de Sacha Inchi “Plukenetia volubilis Linneo” para su aplicación antioxidante para el cuidado del cabello y la piel
(Universidad Privada Norbert Wiener, 2018-08-28) Camacho Caycho, Fanny Isabel; Chamorro Contreras, Ruby Evelyn; Cano Pérez, Carlos Alfredo
Peru is a megadiverse country due to its vast and rich variety of fauna and flora, among which medicinal plants stand out. The latter have been increasingly utilized by the cosmetic industry, giving rise to so-called ecological cosmetics, produced from plants with healing properties such as sacha inchi and uña de gato, among others. The objective of the present study was to design and formulate a dermocosmetic line based on the oil of Plukenetia volubilis L. for application in skin and hair care, given its antioxidant capacity. The dermocosmetic line included shampoo, body cream, and sunscreen, which were developed under safe conditions, resulting in products that remained stable over time. Stability was demonstrated through quality control assessments involving organoleptic, physicochemical, and microbiological analyses. Antioxidant activity was determined using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, showing that the shampoo had an IC50 of 3.777 mg/mL and a TEAC of 14.909/g, the body cream had an IC50 of 1.420 mg/mL and a TEAC of 16.770/g, and the sunscreen had an IC50 of 1.120 mg/mL and a TEAC of 29.868/g. It is concluded that the dermocosmetic line developed at pilot scale with Plukenetia volubilis L. oil meets the required characteristics.
Acceso abierto
Eficacia y seguridad del aceite medicinal de cannabis en pacientes epilépticos refractarios: revisión sistemática y metaanálisis
(Universidad Privada Norbert Wiener, 2023-09-08) Monago Casimir, Fernando; Rojas Delzo, Vicente José; Castillo Soto, Pedro Félix
This study aimed to evaluate the efficacy and safety of medicinal cannabis oil in refractory epileptic patients using a systematic review technique complemented with meta-analysis. Randomized, placebo-controlled clinical trials were identified. The primary outcomes for efficacy were the mean percentage reductions in seizure frequency of ≥50%, and for safety, the adverse events presented. Risk ratios with 95% confidence intervals were estimated using the CASPe method. A total of two clinical trials with 291 participants were included in the meta-analysis. In the cannabidiol group, 64 patients (43.5%) out of 147 (100%) achieved efficacy, compared to 36 patients (25%) out of 144 (100%) in the placebo group [risk ratio 1.74, 95% CI: 1.24-2.44; p=0.001]. For safety, 130 patients (88.4%) in the cannabidiol group experienced at least one adverse event, compared to 104 patients (72.2%) in the placebo group [risk ratio 1.22, 95% CI: 1.09-1.38; p=0.00068]. Adverse events significantly associated with cannabidiol included drowsiness (23.1%), diarrhea (20.4%), decreased appetite (17%), vomiting (10.2%), and pyrexia (6.8%). Adjunctive cannabidiol significantly reduced the mean percentage frequency of seizures and showed a higher rate of adverse events compared to placebo in refractory epileptic patients.
Acceso abierto
Patrones de uso y costes de recursos en pacientes usuarios del aceite de Cannabis spp. que demandan atención por trastornos neurológicos en la asociación de pacientes MACU – Perú 2020
(Universidad Privada Norbert Wiener, 2021-12-09) Cordova Rimayhuaman, Juana Milagros; Flores Escobar, Marizu Fulceda; Collantes Llacza, Adela Marlene
This study, titled "Usage Patterns and Resource Costs in Patients Using Cannabis spp. Oil Who Seek Care for Neurological Disorders at the MACU – Peru Patient Association 2020," had the general objective of determining the usage patterns and resource costs in patients using Cannabis spp. oil who seek care for neurological disorders. To achieve this objective, two questionnaires were applied to 112 patients in a quantitative, retrospective cohort, and longitudinal study. The main results were: The average annual cost of treating neurological disorders with Cannabis sativa oil was S/ 59,331.80 lower than with traditional drugs. The difference between the annual number of episodes before and after using the Cannabis spp. oil was 3,102. The main conclusions were: 40.0% of patients with neurological disorders used 1,860 drops of Cannabis spp. oil per year. The average annual cost per patient for treatment with traditional drugs was statistically higher than with Cannabis sativa oil. The annual number of disease episodes before consuming Cannabis sativa oil was significantly higher than the number of episodes after its consumption.