Examinando por Materia "Postmenopause"

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Acceso abierto
Impact of overweight and/or obesity on the risk of breast cancer in postmenopause
(Universidad Privada Norbert Wiener, 2022-11-10) Ancco Casa, Kemyluz Celia; Bohórquez Medina, Sofia Lorena
Breast cancer begins when breast cells begin to transform into tumor cells, which later begin to invade surrounding tissues and metastasize to different organs of the body. The present secondary research entitled as a critical review: IMPACT OF OVERWEIGHT AND/OR OBESITY ON THE RISK OF BREAST CANCER IN THE POSTMENOPAUSE, had the objective of identifying whether obesity is a factor that predisposes those women who are in the postmenopause to develop of breast cancer The clinical question was: Does overweight and/or obesity have an impact on the risk of breast cancer in the postmenopause? The Evidence-Based Nutrition (NuBE) methodology was used. An information search was carried out using the following search tools such as SCIELO, SCIENCE DIRECT, 94 articles were found, and a selection was subsequently made, leaving 17 articles to be evaluated by the critical reading tool CASPE, finally selecting the study of Cases and Controls entitled Effect of long-term weight gain on the risk of breast cancer across women's entire adulthood as well as hormone-changed menopause stages: A systematic review and dose–response meta-analysis, based on the researcher's experience, has an AI level of evidence and a Strong recommendation. The critical comment gave rise to the conclusion that being overweight and/or has an impact on the risk of breast cancer in the postmenopause, because obesity decreases the same Adiponectin that has anticancer effects.
Acceso abierto
Relación del índice aterogénico de Castelli con la hipertensión en mujeres posmenopáusicas en un policlínico privado de Lima, 2024
(Universidad Privada Norbert Wiener, 2025-09-17) Cosinga García, Guillermo Gianfranco; Borja Velezmoro, Gustavo Adolfo
La presente investigación tuvo como objetivo determinar la relación entre el índice aterogénico de Castelli y la hipertensión arterial en mujeres posmenopáusicas que acuden a un Policlínico Privado de Lima durante el año 2024. El estudio fue de método hipotético deductivo con enfoque cuantitativo de tipo básica con diseño transversal y no experimental. La muestra estuvo compuesta por 166 mujeres posmenopáusicas. Se recolectaron parte de los datos del perfil lipídico (colesterol total y HDL), así como de presión arterial, y se calculó el índice aterogénico de Castelli que se obtiene entre el colesterol total y el HDL. Los resultados evidenciaron que el 6% de las participantes presentaron un riesgo alto según el índice de Castelli y el 49% un riesgo alto. Asimismo, el 35% de las pacientes fueron hipertensas y el 16% prehipertensas. Mediante la prueba de Kolmogórov-Smirnov evidenció que las variables no seguían una distribución normal, por lo que se aplicó la correlación de Spearman, el resultado arrojó un valor de p = 0.036 y un coeficiente Rho de 0.276. Por lo que se concluye que el índice aterogénico de Castelli y la hipertensión en mujeres posmenopáusicas tienen una correlación positiva baja pero significativa.
Acceso abierto
Weight gain as a risk factor for breast cancer in postmenopausal women
(Universidad Privada Norbert Wiener, 2018-08-26) Navarro Céspedes, Cinthia del Rocío; Puchoc Melendez, Miriam Lorena; Glenni Garay, Zarely Zabeli
Quantitative observational and retrospective systematic review, subjected to critical selection, using the GRADE evaluation system for the identification of the degree of evidence, found in the following databases: PubMed, Elsevier, Springer Link, JAMA Network, ASCO, where 10% is a clinical trial, 50% are cohort studies, and 40% are case control studies. Obtaining a high quality of evidence in 10% of a study conducted that comes from the United States, and a moderate quality of evidence in 90%, 4 from the United States, 1 from Norway, 1 from Japan, 1 from France, 1 from Mexico and Australia respectively. Also, of the evidence found, 80% (N=8/10) evidence weight gain as a risk for breast cancer in postmenopausal women. In 20% (N=2/10) no significant evidence was found for weight gain as a risk for breast cancer in postmenopausal women.