Examinando por Materia "Prebiotics"

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Critical review: Effectiveness of prebiotic supplementation in reducing uremic toxins in chronic kidney disease undergoing hemodialysis
(Universidad Privada Norbert Wiener, 2023-03-21) Vásquez López, Maria Lourdes; León Cáceres, Johanna del Carmen
The secondary research titled “Critical Review: Effectiveness of Prebiotic Supplementation in Reducing Uremic Toxins in Chronic Kidney Disease on Hemodialysis” aimed to demonstrate the effectiveness of prebiotic (resistant starch) supplementation in reducing uremic toxins in CKD patients undergoing hemodialysis. The clinical question was: “Does prebiotic supplementation reduce the production of uremic toxins in adult CKD patients on hemodialysis?” The Evidence-Based Nutrition (NuBE) methodology was used, and information was sought from Pubmed, Scielo, Cochrane, Dialnet, and Redalyc, resulting in 598 articles. Ten were chosen for evaluation using the CASPE critical reading tool, and the randomized double-blind clinical trial titled “Resistant starch type-2 enriched cookies modulate uremic toxins and inflammation in hemodialysis patients: a randomized, double-blind, crossover, and placebo-controlled trial” was selected, which has an A I evidence level and a Strong Recommendation grade. The critical commentary highlights that prebiotic supplementation is an innovative alternative to reduce uremic toxins and improve the quality of life in CKD patients on hemodialysis.
Acceso abierto
Critical Review: Effects of prebiotics, probiotics and/or synbiotics to improve the intestinal microbiota and the levels of nitrogenous products in patients with CKD.
(Universidad Privada Norbert Wiener, 2022-05-05) Chumpitazi Alcantara, Cynthia Leonor; Dávila Córdova, Jennifer Estefania
Nutritional intervention in patients with CKD to slow the progression of kidney disease has been little studied. However, today more studies are being conducted to generate additional options for patient benefit. The present secondary research, titled Critical Review: Effects of Prebiotics, Probiotics, and Synbiotics to Improve Gut Microbiota and Nitrogenous Product Levels in Patients with CKD, aimed to identify articles that answer the clinical question: Will nutritional intervention with prebiotics, probiotics, and synbiotics improve gut microbiota and nitrogenous product levels in adults with CKD, with or without dialysis? The methodology used was Evidence-Based Nutrition (EBN). Information was searched in PUBMED, MEDLINE, SCIELO, using the CASPE critical reading tool. The final selection was the Randomized Clinical Trial titled Synbiotics Relieving Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial, which has an A2 level of evidence and a Strong Recommendation Grade, according to the researcher's expertise. The critical commentary concluded that synbiotic therapy helps reduce a specific uremic toxin in patients with CKD and helps regulate gut microbiota.
Acceso abierto
Effect of dietary fiber on the reduction of uremic toxins in adult patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2022-05-25) Laura Ticona, María Elena; León Cáceres, Johanna del Carmen
Chronic kidney disease (CKD) develops due to gradual loss of kidney function. In CKD, a deficiency in dietary fiber intake is a factor that leads to intestinal dysbiosis contributing to uremic toxicity. The present secondary research aims to determine the effect of dietary fiber in reducing uremic toxins in adult patients with CKD. The Evidence-Based Nutrition (EBN) methodology was used. The information search was carried out in Pubmed, Scielo, Redalyc, finding 37 articles, 10 articles being selected, which have been evaluated by the CASPE critical reading tool, selecting the research entitled "The Role of Dietary Fiber Supplementation in Regulating Uremic Toxins in Patients With Chronic Kidney Disease: A Meta-Analysis of Randomized Controlled Trials". The critical commentary allowed to conclude that dietary fiber supplementation decreased the levels of IS, pCS, BUN and AU in patients with CKD, so dietary fiber supplementation is recommended in patients with CKD.