Examinando por Materia "Procalcitonin"

Mostrando 1 - 4 de 4

Acceso abierto
Design of procalcitonin versus markers used for the diagnosis of bacterial sepsis in patients at the Intensive Care Unit of the National Hospital Alberto Sabogal Sologuren, 2015
(Universidad Privada Norbert Wiener, 1905-07-07) Gonzales Vasquez, Jose Marino; Hilario Velasquez, Flor Eduvines; Baltodano Honores, Carlos Alberto
Introduction: Diagnosing sepsis in the Intensive Care Unit remains a major challenge, as it can lead to death due to multiple organ failure. Procalcitonin is a marker used to differentiate bacterial infections from inflammatory processes of other etiologies. The aim of this study was to determine the performance of procalcitonin compared to other markers used to diagnose bacterial sepsis in the Intensive Care Unit of the National Alberto Sabogal Sologuren Hospital in 2015. Methodology: The study was descriptive, comparative, non-experimental, prospective, and cross-sectional. Results: 30 patients from the Intensive Care Unit of the National Alberto Sabogal Sologuren Hospital, with a presumptive diagnosis of sepsis, were studied from January to April 2015. Of these, 26.67% had a positive blood culture, considered the confirmatory test for bacterial sepsis. The performance of the tests was as follows: Procalcitonin (PCT): Sensitivity (S) 87.5%, Specificity (E) 95.45%, Positive Predictive Value (PPV) 87.5%, Negative Predictive Value (NPV) 95.4%. For C-reactive protein (CRP): S 100%, E 0%, PPV 26%, NPV 0%. For the Erythrocyte Sedimentation Rate (ESR): S 100%, E 4.76%, PPV 27.58%, NPV 100%. For white blood cell count: S 75%, E 50%, PPV 35.2%, NPV 84.6%. For neutrophil percentage: S 100%, E 15.78%, PPV 29.63%, NPV 100%. Conclusion: Procalcitonin showed better performance for diagnosing bacterial sepsis compared to other markers used currently in the hospital.
Acceso abierto
Índice neutrófilo/linfocito y procalcitonina en pacientes con sepsis del Hospital Nacional Guillermo Almenara Irigoyen, Lima-2023
(Universidad Privada Norbert Wiener, 2025-02-09) Pillco Quispe, Fray Richard; Huamán Cárdenas, Víctor Raúl
El proyecto de investigación llevado a cabo, tuvo por objetivo “Determinar la relación entre los niveles del índice neutrófilo/linfocito y los niveles de procalcitonina en pacientes hospitalizados con sepsis en el Hospital Nacional Guillermo Almenara Irigoyen, Lima 2023”. El método de investigación utilizado, fue hipotético deductivo; con un enfoque cuantitativo y nivel correlacional. Además, el diseño utilizado fue el no experimental. La población de estudio estuvo constituida por 120 historias clínicas de pacientes con diagnóstico de sepsis, para la muestra se consideró 91 historias clínicas.
Acceso abierto
Mean platelet volume and procalcitonin as prognostic indicators of severity of neonatal sepsis, Hospital Apoyo II, Sullana - Piura 2022
(Universidad Privada Norbert Wiener, 2023-05-28) Benavides Apolo, Gabriela Mercedes; Huamán Cárdenas, Victor Raul
Introduction: Sepsis is a clinical syndrome defined by a dysregulated systemic response to infection, leading to multisystemic inflammatory damage. In Peru, neonatal sepsis is considered the second leading cause of death, with figures close to 22%, and is the leading cause of death in children under 1 year and under 5 years old. Objective: To evaluate the mean platelet volume and procalcitonin as prognostic indicators of the severity of neonatal sepsis in patients treated at Hospital II in Sullana-Piura, 2022. Material and Methods: This will be a deductive hypothetical research with probabilistic analysis, as the results of the study sample will later be generalizable to the study population. The research is observational, and the population consists of 3,704 neonates with a sample of 108. A data collection sheet will be used, and information will be obtained through indicators that help identify the prognosis of neonatal sepsis and understand the relationship between platelet volume and the mechanisms of inflammation in systemic infectious processes. Conclusion: Indicators such as procalcitonin and mean platelet volume can be fundamental in the prognosis of the severity of neonatal sepsis. Early recognition of sepsis and the administration of appropriate treatment with antibiotics, fluids, and vasopressors are essential to reduce neonatal morbidity and mortality.
Acceso abierto
Neutrophil/Lymphocyte index and procalcitonin index in patients with sepsis hospitalized in a private clinic, Lima 2021
(Universidad Privada Norbert Wiener, 2023-05-07) Limaymanta Cárdenas, Milagros del Rosario; Avelino Callupe, Paul Fortunato
Sepsis is one of the leading causes of high hospitalization rates and mortality in intensive care units for both adults and newborns. Sepsis diagnosis is often delayed due to symptom similarities with other conditions. Various diagnostic methods, such as procalcitonin levels and blood culture (hemoculture), are used, but not all healthcare centers have access to these tests due to shortages of materials and high costs. Thus, there is a need to explore the neutrophil/lymphocyte ratio as a low-cost alternative and easy-to-access marker for presuming sepsis diagnosis.