Examinando por Materia "Psychotropic Drugs"

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Acceso abierto
Buenas prácticas de prescripción de psicofármacos en recetas médicas atendidas en oficinas farmacéuticas del distrito de Surquillo, periodo febrero 2015–abril 2016
(Universidad Privada Norbert Wiener, 2017) Espinoza Rivera, Kety Yeanet; Gutierrez Mantarí, Cynthia Johanna; Ramos Cevallos, Norma Julia
The objective of this thesis was to determine compliance with Good Prescribing Practices (GPP) for psychopharmaceuticals in medical prescriptions filled at Pharmaceutical Offices in the Surquillo district from February 2015 to April 2016. A descriptive and observational study was conducted. Data collection was retrospective. 544 medical prescriptions for psychopharmaceuticals were studied. Pharmaceutical Offices in the Surquillo District were analyzed, using a non-probabilistic convenience sampling method where prescriptions that met the inclusion and exclusion criteria were selected. A data form with study indicators was developed. Results: 86.9% of the prescriptions belonged to private health establishments. The most frequent medical specialty was Psychiatrist (53.1%). The most frequent psychopharmaceuticals were: Clonazepam (28.0%), Alprazolam (25.2%), and Sertraline (15.9%). The therapeutic subgroup that predominated was anxiolytics (60.8%). The most used ATC code was N03AE01 (28.0%). Prescriber data were recorded as follows: Full name 99.6%, CMP (Peruvian Medical Association registration) 99.3%, Medical Specialty and Signature 100%, and stamp 97.4% of medical prescriptions. The majority of medical prescriptions did not record patient data. The diagnosis was recorded in 33.3% of medical prescriptions. 77.4% used the International Nonproprietary Name (INN). Therapeutic indications were recorded as follows: dose 84.9%, frequency 79.4%, and duration 37.5%. The conclusion of this thesis demonstrated that a large percentage of doctors do not comply with Good Prescribing Practices.
Acceso abierto
Calidad del sueño y uso de psicofármacos en estudiantes de Farmacia y Bioquímica. Universidad Privada Norbert Wiener. Lima 2022
(Universidad Privada Norbert Wiener, 2023-07-20) Turpo Apaza, Angel Raúl; Cano Pérez, Carlos Alfredo
The objective of this research was to evaluate sleep quality and the use of psychotropic drugs among Pharmacy and Biochemistry students. The research method was deductive, with a quantitative approach and a non-experimental design. A virtual survey was applied to a sample of 325 students. It was found that 58.7% reported poor or very poor subjective sleep quality; 67.3% took more than 30 minutes to fall asleep on one or more nights per week; 36.9% slept between 5 to 6 hours; 39.1% slept more than 6 hours, and 24% slept less than 5 hours; 50.5% had sleep efficiency greater than 85%; 77.2% of respondents reported some type of sleep disturbance; 76.9% did not use medication to sleep; 51.4% reported daytime sleepiness while performing daily activities; and 40.6% indicated experiencing mild mood problems. Finally, 17.2% of respondents reported having used psychotropic drugs in the past month. It is concluded, based on the global score of the Pittsburgh Sleep Quality Index, that 63.7% of students require medical attention and treatment, 24% require medical follow-up, and 4.3% present a severe sleep disorder. Furthermore, the most commonly used psychotropic drugs were anxiolytics and antidepressants.
Acceso abierto
Factores asociados a la prescripción de psicofármacos en adultos mayores atendidos en un hospital nacional de SMP, Lima-2025
(Universidad Privada Norbert Wiener, 2026-01-21) Ascencio Morales, Jhonatan Smith; Rendon Bautista, Gabriela; Ñañez del Pino, Daniel
The study aimed to identify the factors associated with the prescription of psychotropic drugs in older adults treated at a national hospital in San Martín de Porres, Lima, during 2025; an analytical method was used, with a quantitative approach, basic type, non-experimental design, cross sectional cut and descriptive level, including a sample of older adults and using questionnaires and observation guides as instruments; results showed a significant association between the prescription of psychotropic drugs and sociodemographic factors (age, educational level, occupation, income and marital status), biological factors (presence of chronic diseases, functional deterioration, memory problems and dependency), and psychosocial factors (symptoms of depression, discrimination, loneliness and absence of family/friend support), with SSRI antidepressants being the most prescribed drugs; it was concluded that sociodemographic, biological and psychosocial factors are significantly associated with the prescription of psychotropic drugs in older adults, highlighting the importance of comprehensive geriatric mental health care.
Acceso abierto
Identificación de interacciones medicamentosas potenciales en recetas médicas atendidas en la farmacia ambulatoria del Hospital Carlos Lanfranco La Hoz, periodo setiembre–noviembre 2018
(Universidad Privada Norbert Wiener, 2019-03-06) Lovera Tataje, Maria Nicolasa; Herencia Torres, Victor Reynaldo
The objective of this study was to identify potential drug interactions in medical prescriptions filled by the psychiatry service at the outpatient pharmacy of the Carlos Lanfranco La Hoz Hospital from September to November 2018. A retrospective, descriptive, and cross-sectional study was conducted, in which information was collected from medical prescriptions. The study population consisted of 450 medical prescriptions filled by the psychiatry service after applying inclusion and exclusion criteria. The study found that out of the 450 validated prescriptions, 226 had potential drug interactions, for a total of 248 interactions. By gender, 136 (60.2%) were for female patients and 90 (39.8%) for male patients. The prescriptions with the most potential drug interactions were sertraline-clonazepam (50 cases, 20.16%), risperidone-fluoxetine (25 cases, 10.8%), and risperidone-clonazepam (16 cases, 6.5%). According to the mechanism of action, 96 (38.7%) interactions were pharmacokinetic, and 152 (61.3%) were pharmacodynamic. In terms of severity, the interactions were moderate (208 cases, 83.9%), major (40 cases, 16.1%), and minor (0 cases, 0%). Based on documentation type, 16 (6.5%) were excellent, 210 (84.7%) were good, and 22 were fair or poor. This study highlights the importance of identifying drug interactions to prevent health problems related to medication use and to seek the patient's well-being and improvement.
Acceso abierto
Interacciones medicamentosas potenciales en las prescripciones médicas de los fármacos psicotrópicos atendidas en la Farmacia Universal sede Lima, periodo enero–julio 2016
(Universidad Privada Norbert Wiener, 2018-04-27) Palomino Torres, Edwin Manuel; Rojas Chuquilín, Ever Alonso; Rodríguez Arizabal, Julio Cesar
The study was carried out with the purpose of identifying potential drug interactions in medical prescriptions of psychotropic drugs dispensed at Farmacia Universal, Lima branch, during the period January–July 2016. A descriptive, retrospective, cross-sectional study was conducted. The study population consisted of 444 medical prescriptions after applying the inclusion and exclusion criteria. It was observed that, of the 444 psychotropic drug prescriptions, 162 presented drug interactions, with a total of 187 drug interactions identified. The prescriptions with the highest number of potential drug interactions were those containing alprazolam, with 33 interactions, followed by clonazepam, with 20 interactions, and sertraline, with 19 interactions. According to their mechanism of production, 70 interactions (37.4%) were pharmacokinetic and 117 (62.6%) were pharmacodynamic. According to their onset, 142 (75.82%) were of unspecified onset, 37 (19.9%) of slow onset, and 8 (4.3%) of rapid onset. According to their severity, 128 (68.4%) were moderate interactions, 34 (18.2%) unspecified, 13 (7.0%) minor, and 12 (6.4%) major. Furthermore, 143 prescriptions (88.3%) presented one drug interaction, while 19 prescriptions (11.7%) presented two or more interactions.
Acceso abierto
Interacciones medicamentosas potenciales en prescripciones de psicotrópicos dispensados en la botica Super Boticas Hollywood, Lurín 2 enero 2020 a octubre 2021
(Universidad Privada Norbert Wiener, 2022-05-19) Guevara Dávila, José Noé; Quispe Salazar, Mirian Elizabet; Collantes Llacza, Adela Marlene
The objective was to determine the potential drug-drug interactions (PDDIs) in psychotropic prescriptions dispensed at the Hollywood Super Drugstore in Lurín 2 from January 2020 to October 2021. Methodology: The method was deductive, with a descriptive, cross-sectional level, a quantitative approach, a basic type, and a non-experimental design. The population consisted of 700 medical prescriptions, and the sample was 249 prescriptions. The technique used was documentary collection, and the instrument was a data collection form. Results: By type of interaction, pharmacodynamic interactions accounted for 61.7% (409 interactions). By severity, moderate interactions had the highest percentage with 81.4% (540 interactions). In terms of frequency, 1 to 5 interactions per prescription accounted for 92.8% (231 prescriptions). The most prescribed therapeutic group was affective disorders (55.7% or n=330 prescriptions). The most prescribed medication was sodium valproate (29.7% or 176 prescriptions). Conclusion: Potential drug interactions were determined to be predominantly pharmacodynamic (n=409). Furthermore, the highest percentage of severity was moderate (n=540). The frequency of 1 to 5 interactions (n=231), the prevalence of prescriptions for affective disorders (n=330), and the most prescribed medication, sodium valproate (n=176), were also confirmed.
Acceso abierto
Nivel de cumplimiento de las buenas prácticas de prescripción en recetas especializadas de estupefacientes y psicotrópicos en el Hospital Hermilio Valdizan del año 2022
(Universidad Privada Norbert Wiener, 2024-11-04) Pacheco Orejón, Frank Manuel; Juárez Moreyra, Enrique
En la presente investigación se obtuvo el objetivo, determinar el nivel de cumplimiento de las buenas prácticas de prescripción en estupefacientes y psicotrópicos en el Hospital Hermilio Valdizan del año 2022. La presente investigación fue de tipo transversal, de enfoque cuantitativo, observacional, descriptivo y retrospectivo. El diseño es no experimental transversal. La población fue de 600 recetas especiales prescritas en el Hospital Hermilio Valdizan del año 2022. Como técnica de recolección de datos se usó una ficha de recolección de datos validada y aprobada por juicio de expertos, donde la ficha de recolección de datos está dividida en tres partes: del paciente, del medicamento y del prescriptor. Como principales resultados se obtuvo un 96.84% de cumplimiento en la dimensión del paciente, un 96.75% de cumplimiento en la dimensión del medicamento y un 98.81% de cumplimiento en un 98.81%.
Acceso abierto
Psicofármacos más dispensados y trastornos psiquiátricos más frecuentes durante la pandemia en pacientes hospitalizados del Hospital Víctor Larco Herrera 2020–2021
(Universidad Privada Norbert Wiener, 2022-05-18) Cunya Huaman, Dany; Inca Sulla, Juana Julia; Collantes Llacza, Adela Marlene
The objective was to determine the relationship between the most dispensed psychopharmaceuticals and the most frequent psychiatric disorders during the pandemic in hospitalized patients at the Víctor Larco Herrera Hospital from 2020 to 2021. Methodology: The study was analytical, inductive, and deductive at a basic level, with a quantitative, descriptive-correlational approach and a non-experimental-longitudinal design. A total of 317 prescriptions were reviewed using a documentary data collection guide approved by three pharmaceutical chemists. The guide contained 32 items with 'Yes' and 'No' alternatives. Data were initially entered into Excel 16 and then transferred to SPSS version 25 for analysis, where the Pearson's Chi-squared non-parametric test was used. Results: A relationship was found between the prescription of the most dispensed psychopharmaceuticals and the diagnosis of the most frequent psychiatric disorders. The most dispensed psychopharmaceuticals were sertraline, clonazepam, and risperidone. The most frequent psychiatric disorder was depression. The Pearson's Chi-squared non-parametric test (p-value > 0.005) supported the alternative hypothesis (HA) and rejected the null hypothesis (H0). Conclusion: A relationship was established between the most dispensed psychopharmaceuticals and the most frequent psychiatric disorders during the pandemic in hospitalized patients at the Víctor Larco Herrera Hospital from 2020 to 2021.
Acceso abierto
Uso de psicofármacos y calidad de vida en adultos mayores en una cadena de boticas Vida y Salud, Lima 2024
(Universidad Privada Norbert Wiener, 2025-06-09) Castro Conde, Sumiko Karina; Gutarra Chacon, Eva Mercedes; Ramos Jaco, Antonio Guillermo
El objetivo de esta investigación fue evaluar la relación entre el uso de psicofármacos y la calidad de vida en adultos mayores atendidos en una cadena de boticas. Se realizó un estudio transversal, descriptivo y correlacional, en el que participaron 204 adultos mayores seleccionados mediante muestreo probabilístico. Los datos se recolectaron a través de encuestas estructuradas que evaluaron variables como el tipo de psicofármaco, el periodo de esquema prescrito y la presencia de efectos adversos, además de la calidad de vida medida mediante la Escala de Calidad de Vida WHOQOL BREF. Los resultados mostraron que el tipo de psicofármaco no tuvo una relación significativa con la calidad de vida (p = 0,079), aunque los ansiolíticos fueron los más utilizados en todos los niveles de calidad de vida. Sin embargo, se encontró una relación significativa entre el periodo de esquema prescrito y la calidad de vida (p = 0,000, V de Cramer = 0,526), siendo los esquemas más breves los asociados con mejores niveles de calidad de vida. Asimismo, la presencia de efectos adversos tuvo una relación significativa con la calidad de vida (p = 0,000, V de Cramer = 0,326), con mayores niveles bajos y moderados en quienes reportaron efectos adversos. En conclusión, aunque el tipo de psicofármaco no mostró un impacto directo, la duración del tratamiento y los efectos adversos influyeron significativamente en la calidad de vida, destacando la necesidad de un manejo cuidadoso en la prescripción y monitoreo de psicofármacos para optimizar el bienestar de los adultos mayores.