Examinando por Materia "Resistencia betalactámica"

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  • Miniatura
    ÍtemAcceso abierto
    Clinical-epidemiological characteristics of patients hospitalized with urinary tract infections caused by BLEE-producing Enterobacteriaceae at Carlos Lanfranco La Hoz Hospital, 2017
    (Universidad Privada Norbert Wiener, 2019-05-07) Villarreal Guevara, Nathaly Marbelly; Benites Azabache, Juan Carlos
    This research is a descriptive, cross-sectional, and retrospective study. A total of 148 data points from patients were collected, including age, sex, source service, prior antibiotic use, hospitalization time, and the enterobacteria isolated in their urine cultures. The statistical software EpiInfo and Excel were used for frequency analysis and graphical representation. The results showed that the prevalence of patients with UTIs positive for extended-spectrum beta-lactamase (ESBL)-producing enterobacteria was 23.2%. Of the 148 cases, 81.8% were women, the mean age was 49.4 years, 66.2% came from general medicine, the average hospitalization time was 12.3 +/- 13.5 days, and 68.9% of the enterobacteria isolated and positive for ESBL were Escherichia coli. The most frequent comorbidities were diabetes and hypertension, and 26.3% of the patients had received ceftriaxone prior to confirmation of infection by ESBL.
  • Miniatura
    ÍtemAcceso abierto
    Diagnostic performance of chromagar esbl versus the vitek 2 automated system for the phenotypic detection of extended spectrum betal-actamase in urocultures, Lima 2023
    (Universidad Privada Norbert Wiener, 2024-04-28) Tena Contreras, Ruth Araceli; Moya Salazar, Jeel Junior
    Antibiotic resistance in bacteria is a growing public health concern worldwide. A set of factors affects the reduction of antibiotic resistance, with bacteria often showing intrinsic and extrinsic resistance mechanisms to main drugs. One specific type of antibiotic resistance is the production of extended-spectrum beta-lactamases (ESBLs), a resistance mechanism that has emerged as a significant problem in recent years. ESBL production confers resistance to a wide range of beta-lactam antibiotics, and infections caused by ESBL-producing bacteria are associated with increased morbidity, mortality, and healthcare costs. There is currently no consensus on the optimal approach to ESBL detection, as many health centers lack the materials necessary for diagnosis through the mentioned methods. Additionally, the performance of these methods can vary depending on the type of ESBL and the bacterial species being tested. Therefore, there is an important need for continuous evaluation and validation of ESBL diagnostic methods to ensure their accuracy and reliability.