Examinando por Materia "SARS-CoV-2 vaccine"

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    Acceptance and results of the Sars-Cov-2 vaccine during pregnancy and breastfeeding
    (Universidad Privada Norbert Wiener, 2022-02-07) Parvina Hernandez, Pamela Yoselin; Morales Alvarado, Sabrina Ynés
    Objective: To determine the scientific evidence regarding the acceptance and outcomes of the SARS-CoV-2 vaccine during pregnancy and breastfeeding. Materials and Methods: A qualitative bibliographic review was conducted. Information was retrieved from various databases, including Google Scholar, Lilacs, PubMed, Elsevier, Cochrane, Scielo, ScienceDirect, and Microsoft Academic. The study included 42 articles that met the inclusion criteria for the 2021 study period. The Grade system was used to evaluate the quality of each article. Results: There was positive acceptance of the vaccine by pregnant and breastfeeding women. The vaccine demonstrated high effectiveness without complications in pregnant and breastfeeding women. Post-vaccination clinical reactions included common symptoms such as injection site pain, headache, general weakness, and myalgia. Neutralizing antibodies were detected in maternal serum, with placental transfer to the umbilical cord. Additionally, neutralizing and specific antibodies were found in breast milk, providing immune transfer to the infants. Conclusion: The vaccine should be used during pregnancy with complete safety as it provides an immunological response for both the mother and baby. Similarly, during breastfeeding, antibodies were present in breast milk, offering potential protection to the baby.