Examinando por Materia "Sapindaceae"
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Publicación Acceso abierto Efecto antiinflamatorio y capacidad antioxidante del extracto hidroalcohólico del pericarpio de Nephelium lappaceum L. "rambután"(Universidad Privada Norbert Wiener, 2020-01-30) Salazar Barrios, Evelin Patricia; Palomino Ludeña, Mirian; Justil Guerrero, Hugo JesúsThe objective was to determine the anti-inflammatory effect and antioxidant capacity of the hydroalcoholic extract from the pericarp of Nephelium lappaceum L. 'rambutan.' Method: For the anti-inflammatory effect, the 3% carrageenan-induced plantar edema model (Winter et al. modified) was used. Seven groups of six mice were formed. After one hour, 0.1 mL of 3% carrageenan was administered, and the edema of the inflamed paw was measured at 1, 2, 3, and 4 hours. For the antioxidant capacity, the modified Lalitha and Selvam method was used. 6 mL of blood was extracted, and eight groups of three replicates each were prepared. The samples were centrifuged at 1500 rpm for 10 minutes, and the absorbance was measured at 415 nm at 50 and 90 minutes. Results: The 500 mg/kg dose showed the highest anti-inflammatory effect (22.58%) at the 4-hour mark. For antioxidant capacity, the 50 µg/mL concentration yielded the best result at 50 minutes (95.54%), while the 100 µg/mL concentration was the best at 90 minutes (77.95%). Conclusion: The anti-inflammatory effect and antioxidant capacity of the hydroalcoholic extract from the pericarp of Nephelium lappaceum L. 'rambutan' were confirmed.Publicación Acceso abierto Nivel de conocimiento de la acción hipoglucemiante del rambutan (Nephelium lappaceun L.) y uso como terapia complementaria de los pacientes de la botica Capricornio, distrito de San Martin de Porres – Lima, 2022(Universidad Privada Norbert Wiener, 2022-07-08) Astuhuamán Chávez, Kinverlin Estela; Fernández Huerta de Martínez, Miuren Yvett Catherine; Guadalupe Sifuentes de Posadas, Luz FabiolaRambutan is an exotic fruit from Malaysia that is cultivated in the central Peruvian jungle. Metabolites with hypoglycemic activity have been found in its seed and peel. Objective: This study aimed to determine the level of knowledge of the hypoglycemic action of rambutan (Nephelium lappaceum L.) and its use as a complementary therapy for type 2 diabetes among patients of the Capricornio drugstore in the San Martín de Porres district, Lima, in 2022. Methodology: The design was non-experimental, descriptive, cross-sectional, and correlational in scope. A validated data collection instrument was used on a sample of 220 patients who visited the Capricornio drugstore. Results: Positive results were obtained for the four specific hypotheses proposed, so the alternative hypothesis was accepted and the null hypothesis was rejected. Conclusions: The evaluation of patients at the Capricornio drugstore concluded that as knowledge of rambutan's hypoglycemic action increases, the use of complementary therapy also increases, thus confirming the general hypothesis of the study.
