Examinando por Materia "Tolerancia Inmunológica"

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    Seroprotection efficacy of tetravalent vaccine compared to bivalent vaccine in cervical cancer prevention.
    (Universidad Privada Norbert Wiener, 2018-01-27) Mullo Medina, Mónica; Bonilla Asalde, César Antonio
    Objectives: To analyze the evidence on the effectiveness of seroprotection of the tetravalent vaccine compared to the bivalent vaccine in preventing cervical cancer. Materials and methods: The type of research was qualitative, and the study design was a systematic observational, prospective review. The search was based on full-text articles, with a study population of 24 articles and a sample of 10, from the period 2013 to 2017. Articles included randomized controlled trials, systematic reviews, meta-analyses, and cohort studies on the seroprotection of the vaccine in preventing cervical cancer. Results: It shows that all 10 articles reviewed (100%) report significant efficacy in seroprotection of the tetravalent vaccine compared to the bivalent vaccine. Conclusions: 90% of studies related to the tetravalent vaccine compared to the bivalent vaccine in preventing cervical cancer are effective, as they reduced the incidence of HPV, developed prophylactic vaccines, have an acceptable safety profile, surveillance, and a positive impact for achieving useful coverage. 10% of studies conclude that the vaccine only covers some high-risk types of HPV.