Examinando por Materia "Toluene"
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Publicación Acceso abierto Cuantificación de fenoles y ácido hipúrico como indicadores de exposición al benceno y tolueno en trabajadores de carpintería del distrito San Juan de Lurigancho – Lima 2019(Universidad Privada Norbert Wiener, 2021-06-17) Campos Chavarria, Ana Luisa; Ramos Jaco, Antonio GuillermoThe main objective of this study was to determine the concentration of phenols and hippuric acid in the urine of carpentry workers as indicators of exposure to benzene and toluene. The analytical technique used was UV-Vis spectroscopy. The sample consisted of 30 carpentry workers aged between 28 and 54 years with exposure times ranging from 8 to 30 years, to whom an occupational health survey was applied. The average concentration of phenols in urine was 215.1 mg/L, with a minimum of 138.0 mg/L and a maximum of 295.0 mg/L. Similarly, the average concentration of hippuric acid in urine was 2.02 g/L, with a minimum of 1.34 g/L and a maximum of 2.77 g/L. It was found that the levels of phenols and hippuric acid in urine exceeded the maximum permissible values according to the WHO (75 mg/L and 1.4 g/L) in 100% and 96.67% of the samples, respectively.Publicación Acceso abierto Identificación de ácido hipúrico y fenoles en orina de trabajadores con exposición laboral de imprentas del Centro Comercial Lima, Cercado de Lima(Universidad Privada Norbert Wiener, 2018-05-25) Olivera Cueva, Carlos Eduardo; Ramos Jaco, Antonio GuillermoIn this study, we identified the levels of phenols and hippuric acid in the urine of 40 workers employed in printing presses in Cercado de Lima. These workers frequently use organic solvents such as benzene and toluene in concentrations ranging from 1% to 3%. The quantification of total phenols was performed using the spectrophotometric method of Banfi and Marenzi, and hippuric acid was quantified using the Weichselbaum and Probstein titration method. The average of total phenols found was 222.35 mg/L, and hippuric acid was 2.048 g/L. These values indicate exposure to both benzene and toluene, as they exceed the reference values in urine given by the WHO (75 mg/L for phenols and 0.4 to 1.4 g/L for hippuric acid). The toxicological studies were conducted in the toxicology and legal chemistry laboratory of the Faculty of Pharmacy and Biochemistry at Norbert Wiener University.
