Examinando por Materia "Toxinas Urémicas"

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  • Miniatura
    ÍtemAcceso abierto
    Effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease
    (Universidad Privada Norbert Wiener, 2019-11-17) Vargas Marcaquispe, Dina; Ibarra Noreña, Haydeé; Pretell Aguilar, Rosa María
    OBJECTIVE: Systematize evidence on the effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease. MATERIAL AND METHOD: The study is quantitative, with a systematic, observational and retrospective review design; of articles with full text, which identified their grade or quality of evidence according to the Grade System. Likewise, the population was made up of 10 articles that were obtained from the database. Of which 70% are of systematic review design and 30% of randomized clinical trials. RESULTS: Of the 10 articles reviewed, (10/10), 100% demonstrate the effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease. CONCLUSIONS: 10 of the 10 articles respond that probiotics are effective in reducing uremic toxins in patients with chronic kidney disease (CKD); helping to slow the progression of kidney disease and improve heart health, as an adjuvant therapy for CKD, because they cost less and are more acceptable in kidney patients.
  • Miniatura
    ÍtemAcceso abierto
    Systemic review: Efficacy of probiotic supplementation in reducing nitrogenous waste and uremic toxins in patients with chronic kidney disease
    (Universidad Privada Norbert Wiener, 2021-01-19) Rosario Rengifo, Pedro Miguel; Mauricio Alza, Saby Marisol
    Objective: To know the effectiveness of probiotic supplementation in reducing nitrogenous waste and uremic toxins in patients with kidney disease. Materials and methods: Meta-analysis studies and randomized controlled trials were collected from virtual health journals including: Lilacs, BVS Minsa, and PubMed. They were included research evaluating the effect of probiotics on nitrogenous waste and uremic toxins in patients with chronic kidney disease. The GRADE approach was used to determine the quality of the research collected. Results: The information reported in relation to probiotic supplementation did not demonstrate a reduction in nitrogenous waste or uremic toxins, evident in 13 of the selected articles, in which a non-significant decrease was found or no variation was observed in the metabolites studied. Conclusions: It is concluded that the use of probiotics as adjuvant therapy in the nutritional management of chronic kidney disease has not shown proven effectiveness in reducing nitrogenous waste or uremic toxins, therefore it should not be used for that purpose.