Examinando por Materia "Urine"

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Acceso abierto
Leukocyte count by the sedimentation method and its relationship with the Neubauer chamber method in urine collected in the clinical laboratory of the Perinatal Maternal Institute (INMP) of Lima, 2017
(Universidad Privada Norbert Wiener, 2019-08-01) Ramirez Suarez, Klaus Ali Bey; Sandoval Vegas, Miguel Hernán
Urine analysis is the first and most important laboratory test in evaluating a patient with suspected kidney disease, providing valuable data. Examination of urinary sediment is especially useful for diagnosing urinary tract infections, particularly when detecting asymptomatic bacteriuria, and can also be done using the Neubauer chamber for leukocyte counts. Objective: To determine the relationship between leukocyte counts obtained by the sedimentation method and the Neubauer chamber method in urine samples collected at the Instituto Materno Perinatal (INMP) Clinical Laboratory in Lima in 2017. Materials and Methods: A selection of 68 urine samples from pregnant women was made. This is a quantitative, correlational, and prospective study, using the Pearson correlation test to analyze the relationship between leukocyte counts from sediment and the Neubauer chamber method. Results: A correlation value of 0.730 was found between the sedimentation method and the Neubauer chamber method. The Neubauer chamber achieved 100% sensitivity, 32.6% specificity, 46.3% positive predictive value, 100% negative predictive value, and 57% diagnostic certainty, with positive and negative likelihood ratios of 1.48 and 0, respectively. Conclusion: A good correlation was found between the sedimentation method and the Neubauer chamber method for identifying leukocytes, demonstrating that despite a good correlation, the Neubauer chamber does not apply as a diagnostic test.
Acceso abierto
Status of the role of clinical laboratories in the assessment of dysmorphic red blood cells in urinary sediment, Lima - 2023
(Universidad Privada Norbert Wiener, 2023-10-01) Benites Ricra, Miguel Angel; Saldaña Orejón, Italo Moisés
Hematuria is defined by the presence of red blood cells in elevated quantities observed microscopically in the urinary sediment. The dysmorphic (abnormal) characteristic of the red blood cell in urine is a result of its passage through the glomerulus, indicating glomerular-origin hematuria. The initial diagnostic test should include microscopic examination of urinary sediment, the count of red blood cells observed per mm3, and the correct identification of the red blood cell morphology, either normal (biconcave) or dysmorphic with deterioration or deformation, such as vesicles or blisters on the red blood cell membrane, which indicates glomerular-origin hematuria. Currently, only international studies have shown the lack of standardization in methods for detecting and quantifying hematuria, and even difficulties in distinguishing non-glomerular hematuria from glomerular hematuria, as well as recognizing and categorizing dysmorphic red blood cell morphology, leading to discrepancies in clinical laboratories and suboptimal diagnoses.