Examinando por Materia "Vacunas Combinadas"

Mostrando 1 - 3 de 3

Acceso abierto
Efficacy of tetravalent vaccine seroprotection compared to bivalent vaccine in the prevention of cervical cancer.
(Universidad Privada Norbert Wiener, 2018-01-27) Huamán Flores, Kelly Melissa; Mullo Medina, Mónica; Bonilla Asalde, César Antonio
Objectives: To analyze the evidence on the effectiveness of seroprotection of the tetravalent vaccine compared to the bivalent vaccine in the prevention of cervical cancer. Materials and Methods: The study design was qualitative, observational, and prospective. The search was conducted in articles with complete texts, and the study population consisted of 24 articles, with a sample of 10 from the period 2013 to 2017. Included articles included randomized controlled trials, systematic reviews, meta-analyses, and cohort studies regarding the seroprotection of the vaccine in preventing cervical cancer. Results: Of the 10 articles reviewed, 100% showed significant efficacy in the seroprotection of the tetravalent vaccine compared to the bivalent vaccine. Conclusions: 90% of the studies related to the tetravalent vaccine compared to the bivalent vaccine in the prevention of cervical cancer were effective due to the reduction in the incidence of HPV, the development of prophylactic vaccines, an acceptable safety profile, monitoring, and a positive impact in achieving useful coverage.
Acceso abierto
Risk of intussusception due to administration of the pentavalent RV5 vaccine versus the monovalent RV1 vaccine in children under 2 years old
(Universidad Privada Norbert Wiener, 2019-01-06) Gonzales Robles, Yeni Rosy; Pretell Aguilar, Rosa María
90% of studies conclude that there is a risk of intestinal intussusception due to administration of the RV1 and RV5 rotavirus vaccine; of which 50% show that there is a risk of intestinal intussusception for both types of biological RV5 and RV1; the same thing that happens within the first 7 days after application of the 1st dose of the vaccine. 20% of studies show that there is a greater risk of intussusception for the pentavalent vaccine Rotateq (RV5) in an interval of 1 to 7 days after applying the 1st dose and the remaining 20% of studies show that there is a risk of intussusception after application of the vaccine monovalent Rotarix (RV1) in a time interval of 1 week. 10% of studies conclude that current vaccines are effective and safe and pre-licensing studies with RV5 or RV1 did not show an increase in the frequency of intussusception and other serious adverse events; however, constant monitoring is recommended.
Acceso abierto
Seroprotection efficacy of tetravalent vaccine compared to bivalent vaccine in cervical cancer prevention.
(Universidad Privada Norbert Wiener, 2018-01-27) Mullo Medina, Mónica; Bonilla Asalde, César Antonio
Objectives: To analyze the evidence on the effectiveness of seroprotection of the tetravalent vaccine compared to the bivalent vaccine in preventing cervical cancer. Materials and methods: The type of research was qualitative, and the study design was a systematic observational, prospective review. The search was based on full-text articles, with a study population of 24 articles and a sample of 10, from the period 2013 to 2017. Articles included randomized controlled trials, systematic reviews, meta-analyses, and cohort studies on the seroprotection of the vaccine in preventing cervical cancer. Results: It shows that all 10 articles reviewed (100%) report significant efficacy in seroprotection of the tetravalent vaccine compared to the bivalent vaccine. Conclusions: 90% of studies related to the tetravalent vaccine compared to the bivalent vaccine in preventing cervical cancer are effective, as they reduced the incidence of HPV, developed prophylactic vaccines, have an acceptable safety profile, surveillance, and a positive impact for achieving useful coverage. 10% of studies conclude that the vaccine only covers some high-risk types of HPV.