Examinando por Materia "Vacunas contra Hepatitis B"

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Acceso abierto
Effectiveness of the accelerated scheme against hepatitis B compared to the standardized scheme for seroconversion in at-risk population.
(Universidad Privada Norbert Wiener, 2018-08-04) Donayre Navarro, María Aurora del Rosario; Purizaca Ramos, Nora Luz; Avila Vargas Machuca, Jeannette Giselle
Objective: To analyze the evidence on the effectiveness of the Hepatitis B vaccination with an accelerated schedule compared to the standardized schedule for Hepatitis B seroconversion in at-risk populations. Materials and Methods: Observational and retrospective systematic review, the search was restricted to full-text articles, and the selected articles were subjected to critical reading, using the Grade system to assign the strength of recommendation. Results: According to the results obtained from the systematic review, out of a total of 10 articles reviewed, 60% (n=6) demonstrate the efficacy of an accelerated schedule (0,1,2 months) compared to the standardized schedule (0,2,6 months). The studies state that the accelerated vaccination schedule provides high antibody titers in a short time and can be used for high-risk individuals: family members of chronic carriers, healthcare workers, travelers to endemic areas, and individuals with high-risk behaviors in hard-to-reach populations, to overcome the disadvantages of a standardized vaccination schedule with low adherence. Conclusions: The accelerated schedule is more effective compared to the standardized Hepatitis B vaccination schedule in at-risk populations, considering the administration of a booster dose to ensure proper antibody titration. In the country, an accelerated Hepatitis B vaccination schedule (0,1,2 months) is used; however, the reviewed evidence suggests adding a booster dose.
Acceso abierto
Effectiveness of the accelerated scheme against hepatitis B compared to the standardized scheme for seroconversion in at-risk population.
(Universidad Privada Norbert Wiener, 2018-08-04) Purizaca Ramos, Nora Luz; Avila Vargas Machuca, Jeannette Giselle
Objective: To determine the effect of lycopene on total cholesterol levels in patients with hypercholesterolemia at a hospital in Lima in 2017. Quantitative study with an analytical, longitudinal, and prospective design. Sample: Comprised of patients with hypercholesterolemia from the Nutrition clinic. Lycopene was administered through a preparation based on tomato juice with olive oil, which was macerated for approximately 8 hours before being consumed on an empty stomach. The study included 50 patients, 21 received tomato juice with olive oil (TJO) and their usual diet, 14 patients only received tomato juice (TJ) with their usual diet, and 15 received only nutritional counseling regarding a 1,000-calorie diet (D). Differences were found between the first and second cholesterol measurements for the tomato juice and olive oil preparations (p=0.000) and the Diet (p=0.006). No differences were demonstrated between the groups. According to the study, the tomato juice and olive oil preparation and the diet had an effect on cholesterol levels; these recommendations would support patients with cardiovascular diseases and dyslipidemias.