Examinando por Materia "Vacunas contra Rotavirus"

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Acceso abierto
Effectiveness of rotavirus immunization in reducing diarrheal diseases in children under 5 years old
(Universidad Privada Norbert Wiener, 2018-11-04) Córdova Valdez, Eustaquia Saturnina; Sotelo Garay, Elena Martha; Millones Gómez, Segundo Germán
Objective: Systematize the effectiveness of immunization against rotavirus in reducing diarrheal diseases in children under five years of age. Material and Methods: This work was prepared with the method of systematic observational and retrospective review for which a certain number of works that had hierarchies of high and medium evidence were reviewed, synthesizing the achievements obtained by the authors being an essential part of nursing. based on evidence for its rigorous methodology, identifying relevant studies to answer specific questions of clinical practice. Searched in Pubmed, Scielo, BVS, Oxford Academic, Cochrane, Plus, Medline and Google Academic obtaining a population of 20 scientific articles of which a sample of 10 full texts selected from a critical reading was considered, using the GRADE system to assign the strength of recommendation. 20% (n=2) were a systematic review, 70% (n=7) were cases and controls and 10% (n=1) were a randomized controlled trial. Results: Of the 10 selected articles, 10 out of 10 show the effectiveness of immunization against rotavirus, reducing diarrhea caused by rotavirus.
Acceso abierto
Effectiveness of rotavirus vaccine immunogenicity in relation to breastfeeding
(Universidad Privada Norbert Wiener, 2018-08-26) Benavides Bolivar, María del Carmen; Carlos Acuña, Milagros Esther; Rivera Lozada De Bonilla, Oriana
Objective: Systematize the evidence on the effectiveness of the immunogenicity of the rotavirus vaccine against breastfeeding. Methodology/Methods: Observational and retrospective systematic review, the articles were subjected to a critical reading to identify their level of evidence. Results: 10 articles were chosen, 40% (04) correspond to South Africa, 20% (02) Europe and Asia, 10% (01) Pakistan, India, Mexico, respectively. 10 randomized studies were included. 90% of articles state that the immunogenicity of the rotavirus vaccine can be affected or decreased by factors such as breastfeeding and malnutrition. The extent of the effect depends on the maternal titer of anti-rotavirus antibodies in breast milk, as with higher titers found in less developed areas. With 10% of the reviews, in which it was recommended to withhold breastfeeding for up to 1 hour before and after administration, there was no immune response from the infants. Conclusions: It was evident that the decrease in immunogenicity of the rotavirus vaccine could be attributed to several factors, not only breastfeeding; but due to childhood or maternal malnutrition, environmental enteropathy, interference from maternal antibodies and the presence of other intestinal infections; Breastfeeding should still continue.