Examinando por Materia "Vitamina B12"
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Ítem Acceso abierto Effectiveness of vitamin B12 with folic acid or vitamin B6 administration in preventing cognitive decline in elderly adults(Universidad Privada Norbert Wiener, 2019-12-01) Alfaro Henríquez, Alicia Hermelinda; Morveli Mujica, Eufemia; Gamarra Bustillos, CarlosObjective: Systematize the effectiveness of the administration of vitamin B12 plus folic acid or vitamin B6 in the prevention of cognitive deterioration in the elderly. Material and Methods: Systematic observational and retrospective quantitative review, subjected to critical selection, using the Grade evaluation system to identify the degree of evidence, found in the database: PubMed. Of the 10 articles reviewed, 50% (n= 5/10) are systematic reviews, 30% (n= 3/10) are randomized controlled clinical trials, and 20% (n= 2/10) are cross-sectional studies. cohort. According to the results obtained, they come from the countries of China (40%), followed by England, Italy, Australia, the USA, Spain and Korea (10% each). Results: 70% (n=7/10) of the evidence indicates that the administration of vitamin B12 plus folic acid or vitamin B6 improves memory, maintains brain health in healthy older adults, and increases the effectiveness of Parkinson's treatment. 30% (n=3/10) do not demonstrate the effectiveness of these vitamins in the cognitive area of the elderly. Conclusion: the administration of vitamin B12 plus folic acid or vitamin B6 is effective in the memory of patients with mild cognitive impairment, Alzheimer's and Parkinson's; as well as in healthy older adults.
