Examinando por Materia "Zinc"

Mostrando 1 - 8 de 8

Acceso abierto
Critical review: effect of zinc and supplementation on immune function and response
(Universidad Privada Norbert Wiener, 2022-06-27) Rafael Cucche, Susan Sasha; Bohórquez Medina, Andrea Lisbet
The immune system is an integral part of the inflammatory response with a protective function in order to counteract the invasion of pathogenic microorganisms. Likewise, all cells in the body have the potential to participate in the immune response process. On the other hand, zinc is an essential element for most of the processes that occur in organisms. It has recently been noted that, for humans, food is the main source of zinc. So much so that zinc deficiency can be demonstrated in a significant proportion of the population. For this, the principles of evidence-based nutrition were used as a methodology. For this reason, a systematic search was carried out in 5 databases, Scopus, WOS, Pubmed, Embase and Science Direct, from the last 5 years, which allow us to answer the research question. After the selection of articles, they were evaluated through a critical reading tool to determine the degree of recommendation and level of evidence. Finally, the article with the highest degree of evidence is developed in the critical commentary, in order to extract recommendations for the professional practice of nutritionists and other health professionals.
Acceso abierto
Critical review: effect of Zinc and/or vitamin C supplementation as a treatment in the recovery of patients with Covid-19
(Universidad Privada Norbert Wiener, 2022-11-21) Galarza Martel, Ronny Raúl Omar; Bohórquez Medina, Andrea Lisbet
The present work is a secondary research of critical review, which aimed to determine the effect of supplementation with zinc and/or vitamin C as a treatment for the recovery of patients with COVID-19. Evidence-Based Nutrition was used as a methodology. (NuBE), likewise, the systematic search of articles was carried out using Pubmed, Science Direct, Springer Open, Scopus and MDPI as scientific databases, where 55 articles were found, of which 17 were selected to be evaluated by the CASPe tool and in this way a randomized clinical trial titled: “Effect of high-dose zinc and ascorbic acid supplementation vs usual care on symptom length and reduction among ambulatory patients with SARS-CoV-2 infection: The COVID A to Z” was selected. randomized clinical trial", which obtained a level of evidence "I" and a grade of recommendation "Strong" based on the researcher's evaluation in accordance with the application of the CASPe tool, concluding that zinc supplementation and/or vitamin C generates a positive effect in the treatment for the recovery of patients with COVID-19, but it is not statistically significant; Therefore, larger clinical trials must be carried out to demonstrate the importance of said supplementation.
Acceso abierto
EFECTIVIDAD DE LA SUPLEMENTACIÓN DEL ZINC PARA LA PREVENCIÓN DE DIARREA EN NIÑOS MENORES DE 5 AÑOS
(Universidad Privada Norbert Wiener, 2018-07-08) Caja Delzo, Lily Bertha; Matta Solis, Hernán Hugo
Objetivo: Analizar y sistematizar la efectividad de la suplementación del zinc para la prevención de diarrea en niños menores de 5 años. Material y Métodos: Revisión sistemática, sometidos a selección critica, utilizando el sistema de evaluación Grade para la identificación del grado de evidencia, hallados en las siguientes bases de datos: PubMed, Sciencedirect, Scielo, Wiley Online Library, Elsevier, Epistemonikos. De los 10 artículos revisados sistemáticamente el 70% (n= 7/10) son revisiones sistemáticas, el 20% (n= 2/10) son metanalisis y el 10 % (n= 1/10) son estudios primarios. Según los resultados obtenidos de la revisión sistemática realizada en el presente estudio, proceden de los países de EEUU (30%), seguida de Italia (10%), Polonia (10%), Brazil (10%), Perú (10%). Resultados: Las evidencias encontradas, señalan que el 100% (n=10/10) de los artículos revisados refieren la efectividad de la suplementación del zinc para la prevención de diarrea en niños menores de 5 años; los que confirman que estos suplementos pueden ser útiles para tratar la gastroenteritis aguda; asimismo se recomienda que la administración de este producto debe ser independientemente del suero de rehidratación oral y no mezclada. Conclusión: La suplementación de zinc es más efectiva en la prevención de la diarrea en niños menores de 5 años ya que este reducirá la morbilidad y mortalidad.
Acceso abierto
Effective interventions for the prevention and management of oral mucositis in cancer patients
(Universidad Privada Norbert Wiener, 1905-07-09) Pajuelo Coronel, Carmen Guadalupe; Pizarro Paucar, Maribel Felicitas; Mendigure Fernández, Julio
100% of the studies included in the systematic review show that effective interventions for prevention are: Systematic oral hygiene, amifostine, antibiotic tablet or paste, ice tablets, zinc supplements, bicarbonate rinses sodium, cryotherapy, plantain rinses, chlorhexidine rinses, and laser therapy; and for treatment they are: hydrolytic enzymes, morphine rinses, sodium bicarbonate rinses, zinc supplements, cryotherapy, chlorhexidine rinses and the topical application of pure honey.
Acceso abierto
Effectiveness of zinc administration in linear growth in children under 5 years old.
(Universidad Privada Norbert Wiener, 2017-12-03) Cuzcano Carhuapoma, Marlene; Bonilla Asalde, César Antonio
Objective: To systematize the effectiveness of zinc administration on linear growth in children under 5 years of age. Materials and Methods: Observational and retrospective systematic review. A total of 10 articles were selected, with 30% corresponding to Brazil, 30% to multiple countries (Brazil, Cuba, Peru, Ecuador, and Guatemala), (Brazil, Germany, Russia, and the USA), (South Africa and Latin America), 10% found in Sweden, 10% in Indonesia, 10% in Pakistan, and 10% in South Africa. Results: In children with low birth weight, zinc administration has a positive effect. The administration of zinc in children under 5 years of age benefits their linear growth. Zinc can be administered in the following ways: as a fortifier, in combination with micronutrients, which has good synergy, or alone if necessary. In all cases, it benefits children with low height, and zinc should be administered in specific demographic areas to avoid growth delay. Conclusions: According to the systematic reviews, the effects of zinc administration in children under 5 years of age have a positive impact on their linear growth.
Acceso abierto
Effectiveness of zinc supplementation for the prevention of diarrhea in children under 5 years old
(Universidad Privada Norbert Wiener, 2018-07-08) Caja Delzo, Lily Bertha; Taiña Rodriguez, Marisa; Matta Solis, Hernán Hugo
Objective: Analyze and systematize the effectiveness of zinc supplementation for the prevention of diarrhea in children under 5 years of age. Material and Methods: Systematic review, subjected to critical selection, using the Grade evaluation system to identify the degree of evidence, found in the following databases: PubMed, Sciencedirect, Scielo, Wiley Online Library, Elsevier, Epistemonikos. Of the 10 articles systematically reviewed, 70% (n= 7/10) are systematic reviews, 20% (n= 2/10) are meta-analyses and 10% (n= 1/10) are primary studies. According to the results obtained from the systematic review carried out in the present study, they come from the USA (30%), followed by Italy (10%), Poland (10%), Brazil (10%), Peru (10%). . Results: The evidence found indicates that 100% (n=10/10) of the articles reviewed refer to the effectiveness of zinc supplementation for the prevention of diarrhea in children under 5 years of age; those that confirm that these supplements can be useful in treating acute gastroenteritis; It is also recommended that the administration of this product should be independent of oral rehydration serum and not mixed. Conclusion: Zinc supplementation is more effective in preventing diarrhea in children under 5 years of age since it will reduce morbidity and mortality.
Acceso abierto
Efficacy of zinc in the treatment of acute diarrheal diseases in children.
(Universidad Privada Norbert Wiener, 2018-01-27) Aguirre Gonzáles, Aída; Mendigure Fernandez, Julio
Objective: To systematize the available evidence on the efficacy of zinc in children with acute diarrhea. Materials and Methods: This is a systematic review of 10 articles published in indexed journals over the past 10 years, available in the following databases: SciELO, Dialnet, Medline, and NCBI. A total of 10 articles were selected for final review, with 30% originating from Pakistan and 10% each from Ethiopia, India, Switzerland, Bolivia, Brazil, and Spain. Results: All (100%) of the reviewed articles demonstrate that the addition of zinc to the standard diarrhea management protocol reduced the duration of illness and the frequency of bowel movements. Additionally, 30% of the articles report a reduction in fecal output with zinc supplementation. However, 20% of the studies indicate that zinc supplementation increased vomiting, and another 20% highlight improved immune response in children receiving zinc. Conclusion: Zinc supplementation supports the recovery of children with diarrhea according to the reviewed scientific evidence.
Acceso abierto
Zinc supplementation in morbidity and mortality due to Covid-19
(Universidad Privada Norbert Wiener, 2020-12-11) Sucasaca Rojas, Juan Kenty; Bohórquez Medina, Sofia Lorena
Zinc supplementation could help reduce morbidity and mortality in patients affected by COVID-19. This secondary research, titled as a critical review: 'ZINC SUPPLEMENTATION IN COVID-19 MORBIDITY AND MORTALITY,' aims to analyze whether zinc supplementation contributes to preventing exacerbation, controlling symptoms, and improving final outcomes. The clinical question was: What is the effect of zinc supplementation on COVID-19 morbidity and mortality? A critical review was conducted using the NuBE (Evidence-Based Nutrition) methodology. Scientific articles were searched in 'PubMed/MEDLINE, Science Direct, WOS, and SCOPUS,' yielding 43 articles, of which 14 were included in this research and evaluated using 'CASPe' ('Critical Appraisal Skills Programme'), ultimately selecting the meta-analysis titled 'Zinc supplementation and COVID-19 mortality: a meta-analysis,' which has an 'A II level of evidence' and 'Strong Recommendation Grade.' The critical commentary concluded that zinc supplementation in COVID-19 patients could help reduce mortality rates.