Examinando por Materia "o-Ftalaldehído"

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Acceso abierto
Determination of the safe disinfectant Orthophthaldehyde versus Glutaraldehyde used by nurses in the High Level Disinfection Process
(Universidad Privada Norbert Wiener, 1905-07-09) Idrogo Maita, Zaida Karina; Ruiz Campos, Deysi; Gómez Gonzales, Walter Edgar
Objectives: Determine the safe disinfectant Orthophthaldehyde vs glutaraldehyde to be used by nurses in the high-level disinfection process. Materials and Methods: Observational and retrospective systematic review, the search has been restricted to 8 articles with full text, and the selected articles were subjected to critical reading. Published and indexed in scientific databases, dating back to the year 2000 and responding to articles published in Spanish, English and Portuguese. In the final selection, 4 articles were chosen, we found that 25% (01) corresponds to England, with 25% (01) to Spain, with 25% (01) to Brazil and while another 25% (01) we find Japan; Two systematic reviews and two cross-sectional studies were included. Results: 80% of the articles reviewed show that glutaraldehyde, compared to orthophthaldehyde, is the one that produces the most cytotoxicity at work, but that orthophthalaldehyde is still toxic. Orthophthaldehyde vs glutaraldehyde, in both cases its greatest adverse reaction when used is in the respiratory tract Conclusion: of the liquid chemical substances used as high-level disinfectants Orthophthaldehyde vs Glutaraldehyde It was evident that Glutaraldehyde is a volatile product that emanates cytotoxic substances causing effects adverse effects on the person who handles it, while Orthophthaldehyde, being exposed through inhalation, turns out to be a sensitizing this. The direct handling of high-level disinfectant substances focuses exposure on the inhalation route, requiring the use of personal protective equipment.
Acceso abierto
Effectiveness of alternative disinfectants: peracetic acid and ortho-phthalaldehyde compared to glutaraldehyde for achieving optimal and damage-free disinfection in flexible endoscopes
(Universidad Privada Norbert Wiener, 2018-08-25) Alvarez Avalos, Hiozime; Matta Solis, Hernán Hugo
Objective: To systematically analyze the evidence on the effectiveness of alternative disinfectants: peracetic acid and ortho-phthalaldehyde compared to glutaraldehyde for achieving optimal and damage-free disinfection of flexible endoscopes. Materials and Methods: Systematic review of 06 articles from international studies and research, including the most relevant ones according to the level of evidence, restricted to full-text articles. Of the 06 articles reviewed systematically, 50% are systematic reviews, 33% are controlled clinical trials, and 16% are experimental studies. The articles underwent critical reading using the GRADE scale. Results: Of the 60% of reviewed articles, 20% demonstrate that the disinfectants studied are effective in inactivating vegetative microorganisms under the established conditions of use, 20% of the articles demonstrate that preconditions are important for ensuring proper disinfection, and 30% of articles indicate that the use of ortho-phthalaldehyde, like glutaraldehyde and peracetic acid, has been cited in relation to its toxicity, making it unsafe as an alternative. No studies were found reporting damage to endoscopes caused by the disinfectants. Conclusions: Of the 06 articles reviewed, it is evident that the disinfectants peracetic acid and ortho-phthalaldehyde are effective in inactivating microorganisms. Preconditions must exist to ensure proper disinfection. The disinfectants have been cited for their toxicity, and no studies report damage to endoscopes.