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3D Bitemark Analysis in Forensic Odontology Utilizing a Smartphone Camera and Open-Source Monoscopic Photogrammetry Surface Scanning
(Association of Support to Oral Health Research (APESB), 2023-01) Kurniawan, Arofi; Chusid, An’nisaa; Utomo, Haryono; Istiqomah Marini, Maria; Novia Rizky, Rizky; Widayati Prakoeswa, Beshlina Fitri; Hamdani, Janice; Salazar-Gamarra, Rodrigo; Lauria Dib, Luciano; Alias, Aspalilah; Putera Mohd Yusof, Mohd. Yusmiaidil; Marya, Anand
“Bitemark analysis is a challenging procedure in the field of criminal case investigation. The unique characteristics of dentition are used to find the best match between the existing patterned injury and the suspected perpetrator in bitemark identification. Bitemark analysis accuracy can be influenced by various factors, including biting pressure, tooth morphology, skin elasticity, dental cast duplication, timing, and image quality. This review article discusses the potential of a smartphone camera as an alternative method for 3D bitemark analysis. Bitemark evidence on human skin and food should be immediately recorded or duplicated to retrieve long-lasting proof, allowing for a sufficient examination period. Various studies utilizing twodimensional (2D) and three-dimensional (3D) technologies have been developed to obtain an adequate bitemark analysis. 3D imaging technology provides accurate and precise analysis. However, the currently available method using an intraoral scanner (IOS) requires high-cost specialized equipment and a well-trained operator. The numerous advantages of monoscopic photogrammetry may lead to a novel method of 3D bitemark analysis in forensic odontology. Smartphone cameras and monoscopic photogrammetry methodology could lead to a novel method of 3D bitemark analysis with an efficient cost and readily available equipment.“
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“5G Technology in the Digital Transformation of Healthcare, a Systematic Review“
(MDPI, 2023-02-09) Cabanillas-Carbonell, Michael; Pérez-Martínez, Jorge; Yáñez, Jaime A.
“The world is currently facing one of the biggest problems related to health and the quality of healthcare. According to the goals outlined by WHO in the blueprint for sustainable development (SDG3), one of its objectives is to achieve universal health coverage and ensure a healthy lifestyle. In this regard, it is important to monitor and track the impact of applications that help address this problem. This systematic review provides an analysis of the impact of the 5G network on the use of apps to improve healthcare. An analysis of 343 articles was performed, obtaining 66 relevant articles, the articles were categorized into research conducted with fiber optic backbone network as well as future research. The main medical applications were identified as: telesurgery, mobile ultrasound, biosensor technology, robotic surgery and connected ambulance. In addition, it is classified and answer questions such as the most used to improve medical care and health quality, 5G-based applications used in media to improve medical care and health quality, databases and programming languages in telemedicine are the most used in 5G-based applications, the functionality available for telemedicine based on the use of 5G-based applications.“
Acceso abierto
“5G Technology in the Digital Transformation of Healthcare, a Systematic Review“
(MDPI, 2023-02-09) Cabanillas-Carbonell, Michael; Pérez-Martínez, Jorge; Yáñez, Jaime A.
“The world is currently facing one of the biggest problems related to health and the quality of healthcare. According to the goals outlined by WHO in the blueprint for sustainable development (SDG3), one of its objectives is to achieve universal health coverage and ensure a healthy lifestyle. In this regard, it is important to monitor and track the impact of applications that help address this problem. This systematic review provides an analysis of the impact of the 5G network on the use of apps to improve healthcare. An analysis of 343 articles was performed, obtaining 66 relevant articles, the articles were categorized into research conducted with fiber optic backbone network as well as future research. The main medical applications were identified as: telesurgery, mobile ultrasound, biosensor technology, robotic surgery and connected ambulance. In addition, it is classified and answer questions such as the most used to improve medical care and health quality, 5G-based applications used in media to improve medical care and health quality, databases and programming languages in telemedicine are the most used in 5G-based applications, the functionality available for telemedicine based on the use of 5G-based applications.“
Acceso abierto
A bibliometric analysis of 47-years of research on public health in Peru
(Modestum LTD, 2023-03-21) Sevillano-Jimenez, Javier; Carrión-Chambilla, Mario; Espinoza-Lecca, Eduardo; Mori-Quispe, Elizabeth; Contreras-Pulache, Hans; Moya-Salazar, Jeel
“Objectives: To measure Peruvian scientific production on public health in Scopus database. Methods: Bibliometric study using advanced Scopus web search engine (https://www.scopus.com/search/ form.uri?display=advanced). The inclusion criteria were the publications of articles related to public health between 1973 and 2020. The equation was used as a strategy: TITLE-ABS-CLAVE (“public health”) AND AFFILCOUNTRY (Peru) AND (EXCLUDE (PUBYEAR, 2021) OR EXCLUDE (PUBYEAR, 2020)). SCImago journal & country rank was used to determine the impact factor (h-index) and the quartile of the journals identified. The analysis included in SPSS v24.0 included years of publication, institutions, h-index, list of authors with the most publications, publication types, and journals. Results: 903 articles published by 7.5±12.5 authors were included, showing that 74.5% were original articles written mainly in English (77.7%). The publications for the year 1973 and 2019 were 3 (0.3%) and 98 (10.9%), respectively. In addition, it was shown that the most productive institutions were the Universidad Peruana Cayetano Heredia (42.9%) and the Universidad Nacional Mayor de San Marcos (13.1%). The journal with the highest number of Peruvian publications was Revista Peruana de Medicina Experimental y Salud Pública (RPMESP) [Peruvian Journal of Experimental Medicine and Public Health (PJEMPH)] (17.5%) and PLoS ONE (2.88%). Conclusions: The present study showed in the magazines with the highest number of citations and therefore greater visualization, where Peruvian publications in this area were published, with this the future readers can take these magazines into consideration so that their publications have a greater visualization. In addition to this, the study shows the largest institutions that have a great impact on Peruvian publications in public health in Scopus, this invites researchers to analyze the research methodologies that these institutions follow in order to disclose them for reproduction in new entities interested in research.“
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A cross-sectional study to assess the level of satisfaction with virtual education in Peruvian medical students
(Frontiers Media S.A., 2022-10-05) Grados-Espinoza, Pamela; Zila-Velasque, J. Pierre; Soriano-Moreno, David R.; Regalado-Rodríguez, Kateriny Margot; Sosa-Nuñez, Frank; Barzola-Farfán, William; Gronerth, Jim; Guizado, Lucia; Mejia, Christian R.
“Objectives: Education has totally changed in the context of the pandemic. Therefore, the objective of the present study was to evaluate the factors associated with the level of satisfaction with virtual education in Peruvian medical students during COVID-19. Methods: Analytical and cross-sectional study, based on an online survey of students nationwide. We use previously validated instruments to measure the level of satisfaction and stress (EPP-10-c) of students with virtual education. For the associated factors, adjusted prevalence ratios (PR) were estimated using Poisson regression. Results: Of the 1,878 students surveyed, the median age was 21 years, 57.8% (1,086) were women, 34.8% (654) had a high level of satisfaction with virtual education and 10.7% (202) presented high levels of stress. The factors associated with a low level of satisfaction were attending the fifth year of study, the partial and non-virtual adaptation of the university to virtual education, and a high level of stress. On the other hand, the factors associated with a high level of satisfaction were the education platform used and the study method used. Conclusion: Seven out of 10 students presented a low level of satisfaction with virtual education, 1 out of 10 presented a high level of stress. The factors associated with the low level of satisfaction were attending the fifth year of study, the non-virtual and partial adaptation of the university to virtual education, and the high level of stress.“
Acceso abierto
A cross-sectional study to assess the level of satisfaction with virtual education in Peruvian medical students
(Frontiers SA, 2022-10-06) Grados-Espinoza, Pamela; Zila-Velasque, J Pierre; Soriano-Moreno, David R; Regalado-Rodríguez, Kateriny Margot; Sosa-Nuñez, Frank; Barzola-Farfán, William; Gronerth, Jim; Guizado, Lucia; Mejia, Christian R
“Objectives: Education has totally changed in the context of the pandemic. Therefore, the objective of the present study was to evaluate the factors associated with the level of satisfaction with virtual education in Peruvian medical students during COVID-19. Methods: Analytical and cross-sectional study, based on an online survey of students nationwide. We use previously validated instruments to measure the level of satisfaction and stress (EPP-10-c) of students with virtual education. For the associated factors, adjusted prevalence ratios (PR) were estimated using Poisson regression. Results: Of the 1,878 students surveyed, the median age was 21 years, 57.8% (1,086) were women, 34.8% (654) had a high level of satisfaction with virtual education and 10.7% (202) presented high levels of stress. The factors associated with a low level of satisfaction were attending the fifth year of study, the partial and non-virtual adaptation of the university to virtual education, and a high level of stress. On the other hand, the factors associated with a high level of satisfaction were the education platform used and the study method used. Conclusion: Seven out of 10 students presented a low level of satisfaction with virtual education, 1 out of 10 presented a high level of stress. The factors associated with the low level of satisfaction were attending the fifth year of study, the non-virtual and partial adaptation of the university to virtual education, and the high level of stress.“
Acceso abierto
A Functional Assessment Tool to Distinguish Controls From Alzheimer’s Disease in Lima, Peru
(SAGE PUBLICATIONS INC, 2022) Custodio, Nilton; Montesinos, Rosa; Chambergo-Michilot, Diego; Herrera-Perez, Eder; Pintado-Caipa, Maritza; Seminario, Wendy; Cuenca, Jose; Mesía, Laura; Failoc-Rojas, Virgilio E; Diaz, Monica M
Background: The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functional assessment tool for patients with Alzheimer’s disease (AD). We evaluated its performance in controls, Peruvians with MCI or AD. Methods: A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment (MCI), AD or cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’s alpha) and validity were assessed. Results: We enrolled 276 individuals (AD: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressive symptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could not differentiate MCI from controls but did differentiate AD severity. The ADCS-ADL correlated highly with nearly all tools. Conclusions: The ADCS-ADL scale is reliable in a population with AD in Lima, Peru. Future work may validate a tool for Peruvians with lower educational levels.
Acceso abierto
A Functional Assessment Tool to DistinguishControls From Alzheimer’s Disease in Lima,Peru
(SAGE Publications Inc., 2022-06-03) Custodio, Nilton; Montesinos, Rosa; Chambergo-Michilot, Diego; Herrera-Perez, Eder; Pintado-Caipa, Maritza; Seminario, Wendy; Cuenca, José; Mesía, Laura; Failoc-Rojas, Virgilio E; Diaz, Monica M
Background:The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functionalassessment tool for patients with Alzheimer’s disease (AD). We evaluated its performance in controls, Peruvians with MCI orAD.Methods:A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment(MCI),ADor cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’salpha) and validity were assessed.Results:We enrolled 276 individuals (AD: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressivesymptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could notdifferentiate MCI from controls but did differentiateADseverity. The ADCS-ADL correlated highly with nearly all tools.Conclusions:The ADCS-ADL scale is reliable in a population withADin Lima, Peru. Future work may validate a tool forPeruvians with lower educational levels.
Acceso abierto
A nationwide pilot study on breast cancer screening in Peru
(CANCER INTELLIGENCE LTD, 2023-01-09) Araujo, Jhajaira M.; Gómez, Andrea C.; Zingg-De Jongh, Winston; Ausejo, Jhon; Córdova, Iván; Schwarz, Luis J.; Bretel, Denisse; Fajardo, Williams; Saravia-Huarca, Luis G.; Barboza-Meca, Joshuan; Morante, Zaida; Guillén, Juan R.; Gómez, Henry; Cárdenas, Nadezhda K.; Hernández, Lady; Melo, Walter; Villarreal-Garza, Cynthia; Caglevic, Christian; Palacio, Carolina; García, Héctor; Mejía, Gerson; Flores, Claudio; Vallejos, Carlos; Pinto, Joseph A.
“Introduction: A high prevalence of advanced breast cancer (BC) is a common scenario in Latin America. In Peru, the frequency of BC at Stages III/IV is ≈50% despite implementation of a programme for breast cancer screening (BCS) along the country. We carried out a study to assess the feasibility and develop an instrument to evaluate the knowledge, barriers and perception about BCS in a nationwide pilot study in Peru among candidates for BCS. Methods: We conducted a systematic review of 2,558 reports indexed in PubMed, Scopus, Web of Science, Medline-Ovid and EMBASE, regarding to our study theme. In total, 111 were selected and a 51-items survey was developed (eight items about sociodemographic characteristics). Patients were recruited in public hospitals or private clinics, in rural and urban areas of nine departments of Peru. Results: We surveyed 488 women from: Lima (150), Cajamarca (93), Ica (59), Arequipa (56), Loreto (48), Ancash (38), Junín (15), Puerto Maldonado (15) and Huancavelica (14); 27.9% of them were from rural areas. The mean of age was 53.3 years (standard deviation ± 9.1). Regarding education level, 29.8% had primary, 33.2% secondary and 37.0% higher education. In total, 28.7% of women did not know the term ‘mammogram’ and 47.1% reported never receiving a BCS (36.9% from urban and 73.5% from rural population). In women that underwent BCS, only 67% knew it is for healthy women. In total, 54.1% of patients had low levels of knowledge about risk factors for BC (i.e. 87.5% of women respond that injuries in the breast produce cancer). Cultural, economic and geographic barriers were significantly associated with having a mammogram where 56.9% of participants considered a cost ≤ 7 USD as appropriate. Mammogram was perceived as too painful for 54.9% of women. In addition, women with a self-perception of low-risk for BC and a fatalistic perception of cancer were less likely to have a BCS. Conclusion: We found that it is feasible to conduct a large-scale study in Peru. The results of this pilot study highlight an urgent need of extensive education and awareness about BCS in Peru.“
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A rare case of autoimmune dysglycemia syndrome associated with systemic lupus erythematosus and dermatomyositis
(Modestum LTD, 2023-04-09) Paz-Ibarra, José; Concepción-Zavaleta, Marcio; Quiroz-Aldave, Juan Eduardo; Kcomt Lam, Mikaela; Huauya, Edwars Gilvonio; Sueldo Espinoza, Diego; Gago Cajacuri, George
“Autoimmune dysglycemia syndrome (ADS) is a rare condition that presents as episodes of hypoglycemia as well as hyperglycemia and is classified as insulin autoimmune syndrome (IAS) and type B insulin resistance (TBIR). Autoimmunity plays a key role in the pathogenesis ofthis disorder, as evidenced by the presence of autoantibodies against endogenous insulin or the insulin receptor, and by its association with rheumatologic disorders. Treatment usually includes glycemic control and immunomodulatory agents. We report a case of a 31-year-old woman who was admitted for severe hypoglycemia. Further workup revealed underlying systemic lupus erythematosus (SLE) with renal involvement. During hospitalization, she continued to experience episodes of fasting hypoglycemia, as well as episodes of postprandial hyperglycemia. Hypoglycemia associated with a high serum insulin concentration and positive anti-insulin antibodies were consistent with IAS. Likewise, hyperglycemia and hypoglycemia in association with weight loss, acanthosis nigricans, polycystic ovarian syndrome, and normotriglyceridemia strongly suggested TBIR, although testing for antibodies against the insulin receptor was not available in Peru. Immunosuppressive therapy and metformin were indicated, resulting in remission of SLE and ADS. Years later, the patient exhibited features of dermatomyositis, such as Raynaud’s phenomenon, muscular weakness, heliotrope exanthema, and elevated muscle enzymes. Once again, the patient received immunosuppressive therapy. ADS is an infrequent cause of hypoglycemia, and the coexistence of its two pathophysiological mechanisms in a patient with SLE and subsequent development of dermatomyositis is even more rare. Our case is the first one reported describing this association.“
Acceso abierto
“A Systematic Review of Earned Value Management Methods for Monitoring and Control of Project Schedule Performance: An AHP Approach “
(MDPI, 2022-11-17) Mayo-Alvarez, Luis; Alvarez-Risco, Aldo; Del-Aguila-Arcentales, Shyla; Sekar, M. Chandra; Yáñez, Jaime A.
“: Successful project management depends on ensuring the project’s objectives. Within these objectives, technical success is associated with achieving the expectations of the project baseline. The baseline of the project is made up of the definition of the scope (WBS), time (schedule) and costs (S curve) of the project. Directly, the project is expected to be technically successful if it manages to deliver its full scope on schedule and without associated cost overruns. Baseline performance management is how project managers track and control the progress of deliverables, timelines and associated costs. In a traditional approach, for waterfall-type projects that use the critical path paradigm, the baseline performance management tool par excellence is earned value management (EVM). Earned value management, in practice, works well when project costs are monitored and controlled; however, applying this approach to measure the status of the schedule presents serious inconsistencies. Over the last several decades, different variations of the original earned value have been developed to overcome some of these inconsistencies when used to measure project schedule status. Within these variations, we have the critical path earned value; the work in progress earned value; the critical path earned value and the work in progress; the earned schedule; and the critical path earned schedule. Each of these proposals tries to address some weakness of the original earned value management applied to time monitoring and control, for example, considering critical tasks as a focus on monitoring the progress of the schedule, solving the problem of task recognition late finishers, reporting schedule variances in time units and measuring adherence to the project’s schedule (P factor). Due to the exposed situation, it is necessary to determine which alternative of the versions of the original earned value is the most appropriate for the management of the project schedule, considering that there are several evaluation criteria that must be considered. In the present research, a systematic review and comparison of EVM and its variations for measuring project baseline schedule performance are performed to determine the most suitable methods for monitoring and controlling the project baseline schedule. For this purpose, the analytic hierarchy process (AHP) is used, and five comparison criteria are considered: schedule variation focused on critical tasks, recognition and measurement of the delay of tasks that finish late, schedule variation in time units, measurement of schedule adherence (P factor) and software support and development. The result of the AHP performed for comparing the methods shows that the best method for monitoring and controlling the project baseline schedule is the critical path earned schedule because it behaves adequately in comparison with the other methods for the evaluated comparison categories.“
Acceso abierto
“A Systematic Review of Earned Value Management Methods for Monitoring and Control of Project Schedule Performance: An AHP Approach “
(MDPI, 2022-11-17) Mayo-Alvarez, Luis; Alvarez-Risco, Aldo; Del-Aguila-Arcentales, Shyla; Sekar, M. Chandra; Yáñez, Jaime A.
“: Successful project management depends on ensuring the project’s objectives. Within these objectives, technical success is associated with achieving the expectations of the project baseline. The baseline of the project is made up of the definition of the scope (WBS), time (schedule) and costs (S curve) of the project. Directly, the project is expected to be technically successful if it manages to deliver its full scope on schedule and without associated cost overruns. Baseline performance management is how project managers track and control the progress of deliverables, timelines and associated costs. In a traditional approach, for waterfall-type projects that use the critical path paradigm, the baseline performance management tool par excellence is earned value management (EVM). Earned value management, in practice, works well when project costs are monitored and controlled; however, applying this approach to measure the status of the schedule presents serious inconsistencies. Over the last several decades, different variations of the original earned value have been developed to overcome some of these inconsistencies when used to measure project schedule status. Within these variations, we have the critical path earned value; the work in progress earned value; the critical path earned value and the work in progress; the earned schedule; and the critical path earned schedule. Each of these proposals tries to address some weakness of the original earned value management applied to time monitoring and control, for example, considering critical tasks as a focus on monitoring the progress of the schedule, solving the problem of task recognition late finishers, reporting schedule variances in time units and measuring adherence to the project’s schedule (P factor). Due to the exposed situation, it is necessary to determine which alternative of the versions of the original earned value is the most appropriate for the management of the project schedule, considering that there are several evaluation criteria that must be considered. In the present research, a systematic review and comparison of EVM and its variations for measuring project baseline schedule performance are performed to determine the most suitable methods for monitoring and controlling the project baseline schedule. For this purpose, the analytic hierarchy process (AHP) is used, and five comparison criteria are considered: schedule variation focused on critical tasks, recognition and measurement of the delay of tasks that finish late, schedule variation in time units, measurement of schedule adherence (P factor) and software support and development. The result of the AHP performed for comparing the methods shows that the best method for monitoring and controlling the project baseline schedule is the critical path earned schedule because it behaves adequately in comparison with the other methods for the evaluated comparison categories.“
Acceso abierto
A systematic review of mental health in rural Andean populations in Latin America during the COVID-19 pandemic
(Frontiers Media SA, 2023-08-17) Moya-Salazar, Jeel; Jaime-Quispe, Alexis; Cañari, Betsy; Moya-Espinoza, Jeel G.; Contreras-Pulache, Hans
“Background: COVID-19 has been causing mental health problems around the world, with rural and indigenous peoples likely to be the most aected. This systematic review synthesizes and critically analyzes the existing literature on mental disorders in the rural Andean population in Latin America. Methods: A systematic review with narrative synthesis was carried out following the PRISMA guidelines. We searched nine databases (PubMed/MEDLINE, Scopus, EMBASE, ScienceDirect, Web of Science, Cochrane, Scielo, LILACS, and Latindex), five public prepublication servers (SocArXiv, medRxiv, bioRxiv, SportRXiv, and Preprints), ALICIA, and Google Scholar for articles that included the analysis of mental health problems using data collected from the rural Andean population in Latin America. These were eligible for inclusion. Articles that included NonLatin American populations (including European or African migrants) and studies conducted prior to the COVID-19 pandemic (since the declaration of national lockdown) were excluded. Results: A total of 23,761 articles were retrieved, 14 of which met the inclusion requirements. Most were cross-sectional (n = 12) and related to anxiety (n = 9), depression (n = 8), and stress (n = 5). The mental health analysis of 5,976 rural dwellers from four countries in Latin America also included gray literature studies (n = 7) that allowed the quantification of mental health problems in adults (n = 7) and adolescents/children (n = 4). Only one study was multinational, and the quality of publications varied. Despite the high frequency of anxiety, depression, and stress symptoms among rural Latin American populations during COVID-19, published research is very limited. This review found preliminary evidence that the frequency of anxiety (45%), depression (27.6%), and stress (33.1%) in the rural population was associated with pandemic restrictions across countries. Measures of other psychiatric problems, such as distress or suicidal ideation, cannot be estimated. Conclusion: Regional-wide studies investigating changes in the frequency of symptoms of mental health problems in the context of the COVID-19 pandemic are warranted to inform culturally adapted prevention strategies. This study is limited to a narrative synthesis and may be subject to publication bia“
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Academic Directors Facing Internet Addictions, Learning and Health Promotion
(Richtmann Publishing Ltd, 2023-03-05) De Jesus Garcia Varela, Guillermo; Llópiz Guerra, Karel; Requeiro Almeida, Reinaldo; Saavedra-Lopez, Miguel A.; Calle-Ramirez, Xiomara M.; Hernandez, Ronald M.; Morante Becerra, Lydia
The result that is presented is expressed from a bibliographic review of works published during the last two years 2020-2022 and, through which it was possible to verify the relationships that are established between the work of the Academic Directors, before the latent challenge and visible that is the crossroads of Internet addictions, by university students, increased in the stage already overcome of social isolation imposed by Covid 19 but, with emphasis on the achievement of learning at this high educational level, its risks and consequent decreases in the attacks that occur as a result of procrastination. All associated with the addictive phenomenon, in a projection of health promotion that the current, humanistic, modern and developing university should not give up in any way, being precisely in this direction an unavoidable pillar of social development, which lies precisely in the high professional qualification. of the new generations committed to a prosperous and sustainable social change.
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Acanthamoeba spp. un agente oportunista en infecciones humanas
(Universidad Privada Norbert Wiener, 2019-09-30) Cabello Vílchez, Martín
Las amebas de vida libre (AVL) se encuentran ampliamente distribuidas en la naturaleza, siendo Acanthamoeba spp. el género más aislado del suelo, aire, aguas tratadas para consumo, agua de mar, lagos y aguas termales. El presente trabajo aborda las características de Acanthamoeba spp., su biología, las patologías que afectan a humanos; además, el diagnóstico microbiológico y molecular, que es una herramienta que ha venido mejorándose con el avance de la tecnología. La clave es la identificación de la ameba, para lograr una buena intervención clínica y terapéutica. Finalmente exponemos las combinaciones terapéuticas exitosas en los escasos reportes clínicos existentes.
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Acceptability of yacon flakes (Smallanthus sonchifolia) for dietary use with inulin
(Rynnye Lyan Resources, 2022-04-28) Velásquez-Gamarra, J.; Lozada-Urbano, M.
“This study aimed to elaborate on yacon flakes and determine the proximal composition of fresh yacon and final flakes, made at different temperatures (120°C, 150°C and 180°C) for 20 mins. We measured the acceptability of the sensory attributes: taste, texture, odour and colour and the global acceptability at the laboratory level, using semi-trained panellists and an unstructured hedonic scale. The acceptability of the flakes was measured at different temperatures. Our results indicate that the flakes made at 180°C had the highest acceptance (87%), and the flakes made at 120°C had 80% of unacceptability. Our data were analysed according to the analysis of variance (ANOVA) and Tukey's test. We found significant differences between the averages of the taste scores (T0:7.1; T1:7.6; T2:6.7; T3:4.6), p<0.05; texture (T0:7.1; T1:7.2; T2:5.7; T3:4.5), p<0.05; and odour (T0:7.2; T1:7.6; T2:5.1; T3:3.3), p<0.05. The amount of fructooligosaccharides on a fresh basis was Ⱦ±SD (31.60±0.650) and on a dry basis (37.44±1DS). Microbiological analysis shows that the flakes are fit for human consumption. It is concluded that yacon flakes contain significant amounts of inulin, being a good substitute alternative for the preparation of snack-type dietetic products“
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Actitud hacia la investigación en la facultad de ciencias de la salud de la Universidad Privada Norbert Wiener, 2017
(Universidad Privada Norbert Wiener, 2019-06-02) Arellano-Sacramento, César; Hermoza-Moquillaza, Rocío Victoria; Elías-Podestá, Mario; Ramírez-Julca, Máximo; Hernández, Harold
La investigación es base fundamental en el progreso de la ciencia, y la universidad es la institución que debe alentar a sus estudiantes a realizarla. El objetivo del presente estudio fue determinar la actitud hacia la investigación de los estudiantes de la Facultad de Ciencias de la Salud de la Universidad Privada Norbert Wiener (UPNW) en Lima, 2017. Es un estudio cuantitativo, observacional, transversal. Los sujetos fueron 1300 estudiantes de la Facultad de Ciencias de la Salud (excepto Medicina Humana), del V al X ciclo académico, hombres y mujeres, de entre 18 y 50 años, quienes accedieron a la ficha de recolección de datos a través de la plataforma virtual. El instrumento utilizado fue originalmente dirigido a alumnos de la carrera de odontología y en forma presencial; por ello, se realizó una validación de constructo en este nuevo grupo poblacional (estudiantes de la Facultad de Ciencias de la Salud), de lo que resultó un nuevo instrumento de 13 ítems con validez y confiabilidad comprobada por el estudio. Se procedió también a calcular un baremo. El 80,2 % de los sujetos fueron mujeres. Se evidencia menos participación de estudiantes en tanto se acercan al último ciclo. La mayor cantidad de sujetos fueron de la carrera de Odontología (23,2 %). Hubo semejanza en la frecuencia de rangos de edad “hasta 23 años” y “de 24 a 27” (26,1 % y 27,2 %, respectivamente). El 50,9 % de los estudiantes evidenciaron una actitud regular hacia la investigación.
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Actitudes del autocuidado de pacientes con tuberculosis en enfermeros peruanos luego de un brote hospitalario
(Editorial Ciencias Medicas, 2023-06) Siesquen, Jessica J.; Moya-Salazar, Jeel; Ubidia-Incio, Roberto; Rojas-Zumaran, Víctor; Moya-Salazar, Belén; Contreras-Pulache, Hans
“Introducción: La tuberculosis es una de las principales causas de morbimortalidad en todo el mundo. Las medidas de prevención son clave para evitar su propagación y el contagio entre profesionales de salud. Objetivo: Determinar las actitudes del autocuidado sobre la tuberculosis en el personal de enfermería luego de un brote infeccioso hospitalario. Métodos: Estudio transversal, en personal de enfermería (n= 94; personal técnico n= 44; 46,8 %). Se incluyó al personal de enfermería voluntario > 18 años, de ambos sexos, que trabaje en el Departamento de Emergencia. Se usó el cuestionario de 15 ítems de Valle (2017), para estimar los conocimientos y actitudes sobre el autocuidado, 3 dimensiones: prevención, diagnóstico y tratamiento de la tuberculosis. Resultados: El promedio de edad de los participantes fue de 44,7 ± 8,8 años, el 88,3 % mujeres y el tiempo promedio de trabajo fue 11,2 ± 7,8 años. Se hallaron diferencias entre los años de servicio, entre los técnicos (8,55 ± 7,94 años) y profesionales (13,48 ± 6,98 años) (p< 0,001). El 100 % presentaron actitudes de aceptación del autocuidado en todas las dimensiones. El 4,5 % y el 27,3 % de técnicos presentaron actitudes de indiferencia en la dimensión diagnóstico y tratamiento de tuberculosis (p= 0,001). Conclusiones: Existen actitudes favorables en el personal de enfermería sobre autocuidado de la tuberculosis luego de un brote en un hospital de Lima, aunque en técnicos de enfermería se reportan actitudes de indiferencia en el diagnóstico y tratamiento de tuberculosis.“
Acceso abierto
Acute Hepatic and Renal Toxicity Assessment of Euphorbia huanchahana (Klotzsch & Garcke) Boissier (Huachangana) in Holtzman Rats
(MDPI, 2022-06-30) Villafuerte, Graciela; Ñañez, Daniel; Félix, Luis M.; Moya-Salazar, Marcia M.; Torres-Véliz, Ernesto R.; Ramos, Antonio G.; Contreras-Pulache, Hans; Moya-Salazar, Marcia M.
Background:Euphorbia huachahana (Klotzch & Garcke) Boissier (Huachangana)(EhKGBh)has been used for over a century for medicinal purposes in the Peruvian population; however, itssafety and possible toxic effects of use have not been reported. The purpose of this study was todetermine the acute hepatic and renal toxicity of EhKGBh in Holtzman rats. Methods: Analyticaland experimental study. The population consisted of 52 rats of both sexes weighing between 300 and350 g divided into four groups: G1 and G2 EhKGBh groups (26 rats each) and two control groups(10 rats each). The experimental group was administered EhKGBh at a single dose of 2000 mg/kg P.O.to demonstrate toxicity during the 14-day follow-up. A daily assessment of alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin (TBIL), andconjugated bilirubin (CBIL) was performed. Results: Evaluation of the liver tissue showed mildchanges in inflammation, predominantly vascular, with small clots. Kidney tissue did not showinflammatory or necrotic changes. However, we showed differences in the weight of the rats betweenboth groups (p< 0.004) and significant increases in TBIL (0.98–1.07 mg/dL), CBIL (0.43–0.45 mg/dL),AST (126.4–141.8 U/L), and ALP (254–298 U/L) but not ALT (39.7–41.1 U/L) (p< 0.05). Conclusion:The single dose of EhKGBh extract at 2000 mg/kg has no toxicity, and there is no change in tissuetoxicity during the 14-day follow-up.
Acceso abierto
Acute Hepatic and Renal Toxicity Assessment of Euphorbia huanchahana (Klotzsch & Garcke) Boissier (Huachangana) in Holtzman Rats
(MDPI, 2022-06-30) Villafuerte, Graciela; Ñañez, Daniel; Félix, Luis M.; Moya-Salazar, Marcia M.; Torres-Véliz, Ernesto R.; Ramos, Antonio G.; Contreras-Pulache, Hans; Moya-Salazar, Marcia M.
Background:Euphorbia huachahana (Klotzch & Garcke) Boissier (Huachangana)(EhKGBh)has been used for over a century for medicinal purposes in the Peruvian population; however, itssafety and possible toxic effects of use have not been reported. The purpose of this study was todetermine the acute hepatic and renal toxicity of EhKGBh in Holtzman rats. Methods: Analyticaland experimental study. The population consisted of 52 rats of both sexes weighing between 300 and350 g divided into four groups: G1 and G2 EhKGBh groups (26 rats each) and two control groups(10 rats each). The experimental group was administered EhKGBh at a single dose of 2000 mg/kg P.O.to demonstrate toxicity during the 14-day follow-up. A daily assessment of alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin (TBIL), andconjugated bilirubin (CBIL) was performed. Results: Evaluation of the liver tissue showed mildchanges in inflammation, predominantly vascular, with small clots. Kidney tissue did not showinflammatory or necrotic changes. However, we showed differences in the weight of the rats betweenboth groups (p< 0.004) and significant increases in TBIL (0.98–1.07 mg/dL), CBIL (0.43–0.45 mg/dL),AST (126.4–141.8 U/L), and ALP (254–298 U/L) but not ALT (39.7–41.1 U/L) (p< 0.05). Conclusion:The single dose of EhKGBh extract at 2000 mg/kg has no toxicity, and there is no change in tissuetoxicity during the 14-day follow-up.