Systematic review and meta-analysis of randomized, controlled trials on the effects of soy and soy products supplementation on serum adiponectin levels
![Thumbnail](/bitstream/handle/20.500.13053/6922/1-s2.0-S1871402122001722-main.pdf.jpg?sequence=4&isAllowed=y)
View/ Open
Download
(application/pdf: 727.7Kb)
(application/pdf: 727.7Kb)
Date
2022-07-07Author(s)
Mahmudiono, Trias
Khaydarov, Nodirjon Kadirovich
Jasim, Saade Abdalkareem
Hammid, Ali Thaeer
Failoc-Rojas, Virgilio E.
Shalaby, Mohammed Nader
MehranNouri, Behrooz Jannatg
Abdulmnannan Fadel j
Metadata
Show full item recordAbstract
“ackground and aims: Our aim in this meta-analysis was to determine the effect of soy and soy product
supplementation on serum adiponectin levels.
Method: A systematic search was conducted using Medline (PubMed and Web of Science), Scopus, and
Cochrane Library for eligible trials up to August 2020. A random-effects model was used to pool
calculated effect sizes.
Results: Seven trials were included in the overall analysis. Our analysis showed that soy and soy product
supplementation did not significantly affect adiponectin concentrations (WMD ¼ 0.77 mg/ml, 95%
CI: 0.61, 2.15, P ¼ 0.27) in comparison with a placebo. The between-study heterogeneity was high (I2:
68.2%, P ¼ 0.004). Subgroup analysis, based on participants’ health status and duration of the supple-
mentation, could not detect the potential source of the observed heterogeneity. In addition, subgroup
analysis showed that the effect was not statistically significant in all subgroups.
Conclusion: Overall, soy and soy product supplementation did not change the circulatory adiponectin
levels. In addition, the results were not affected by the participant's health status and duration of sup-
plementation. However, further studies are needed to confirm the present results“
Collections
- SCOPUS [380]