Examinando por Autor "Chavez Anastacio, Dorys Isabel"

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    Comparative study of automated leukocyte differential count and reference method in the hematology laboratory of the National Institute of Neoplastic Diseases, 2021
    (Universidad Privada Norbert Wiener, 2021-12-09) Chavez Anastacio, Dorys Isabel; Champa Guevara, Cesar Alfonso
    The microscopic evaluation of a peripheral blood smear is a diagnostic tool in the hematology laboratory. Automated analyzers mark results for a significant proportion of samples and require confirmation through smear review. Therefore, each clinical laboratory needs to verify the reliability of the automated white blood cell differential count (WBC DC) and compare it with the reference method. Objective: To determine if there is a significant difference between the automated white blood cell differential count and the reference method in the Hematology Laboratory of the National Institute of Neoplastic Diseases, 2021. Methods: A prospective cross-sectional study will be conducted at the Hematology Laboratory from October to December 2021. Data will be analyzed using Excel templates, and the following will be performed: (1) For determining the association between two variables with a normal distribution, Pearson correlation will be used, while Spearman’s correlation will be applied if the data does not follow a normal distribution. (2) To compare methods, the standard error of proportion with 95% confidence intervals will be calculated for each cell type. (3) For comparing paired means, statistical significance will be determined using a p-value < 0.05 (Student’s t-test). (4) For analyzing bias (systematic error), the regression equation will be considered.