Examinando por Autor "Guillén Sulca, Walter Roberto"
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Publicación Acceso abierto Equivalencia farmacéutica de medicamentos multifuentes de sildenafilo de 50 mg que se dispensan en el distrito de San Juan de Miraflores – San Juan zona D en los meses de noviembre y diciembre 2017(Universidad Privada Norbert Wiener, 2018-09-06) Huatuco Amez, Olivia Patrich; Guillén Sulca, Walter Roberto; Cárdenas Orihuela, Robert ArmandoWhen performing the pharmaceutical equivalence of 50 mg sildenafil multi-source medicines dispensed in the district of San Juan de Miraflores during the months of November and December 2017, the objective was to evaluate in vitro the multi-source sildenafil medicines. This drug was chosen because, in recent years in Lima—particularly in the district of San Juan de Miraflores, according to pharmaceutical staff reports—it has been sold with great freedom, and since it is dispensed under different brands, it was necessary to determine whether equivalence existed in relation to the innovator. The methodology used included the corresponding parameters established by the United States Pharmacopeia for solid pharmaceutical forms, evaluating the external aspects and the physical parameters of the tablets, such as weight variation, hardness, disintegration, and friability. The results obtained in this study demonstrated that these pharmaceutical forms are similar with respect to these parameters, meeting the official specifications. The values obtained fall within the accepted averages for oral formulations of 50 mg sildenafil.
