Examinando por Autor "Julca Rupay, Marlene Rosario"

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    Effect of oral vitamin d supplementation on survival of adult colorectal cancer patients.
    (Universidad Privada Norbert Wiener, 2020-12-11) Julca Rupay, Marlene Rosario; Palma Gutiérrez, Edgardo Jhoffire
    This critical review aimed to analyze the effect of oral vitamin D supplementation and its role in the survival of adult patients with colorectal cancer. The clinical question was: Does oral vitamin D supplementation increase survival time in adult patients with colorectal cancer? The Evidence-Based Nutrition (NuBE) methodology was used. Information was searched in Medline, Wiley Online Library, HINARI, Scielo, and Redalyc, finding 225 articles, of which 6 were selected and evaluated using the CASPE critical reading tool. The randomized clinical trial titled 'Effect of high-dose vs. standard-dose vitamin D3 supplementation on progression-free survival in patients with advanced or metastatic colorectal cancer: The SUNSHINE randomized clinical trial' was chosen, possessing a level of evidence I and a strong recommendation grade. The critical commentary concluded that high-dose vitamin D improved survival in colorectal cancer patients compared to those who consumed the standard dose. Further studies are needed to extrapolate these results to the general population.