Examinando por Autor "Moscoso Mujica, Gladys Angélica"

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Actividad antimicrobiana del extracto etanólico de la raíz de Dracontium spruceanum (Schott) G.H. Zhu “jergón sacha” sobre cepas ATCC de Pseudomonas aeruginosa, Escherichia coli y Staphylococcus aureus, Lima 2024
(Universidad Privada Norbert Wiener, 2025-07-17) Bautista Laura, María del Carmen; Moscoso Mujica, Gladys Angélica
The root of the Dracontium spruceanum species Jergón sacha is found in the tropical forests of Peru and is widely used in traditional medicine. It is frequently used by local residents, and there is little research on its antibacterial activity. Furthermore, there are increasing reports of high resistance to the use of synthetic antimicrobials; therefore, the aim is to provide a natural antimicrobial alternative. The objective of this study was to determine the antimicrobial activity of the ethanolic extract of the root of Dracontium spruceanum (Schott) G.H. Zhu “jergón sacha” on ATCC strains of Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus, Lima 2024. In the methodology, the ethanolic extract of the root was obtained and the antimicrobial activity was evaluated at different concentrations of the dry extract by agar diffusion using ATCC strains of Gram positive and Gram negative microorganisms. In the results, the extract in P. aeruginosa showed greater activity than the synthetic antibiotic Cefepime 30 ug with 2.68 mm (p < 0.05); and antimicrobial activity greater than 50% than gentamicin (p < 0.05). In S. aureus it showed antimicrobial activity close to Vancomycin and Oxacillin (p > 0.05); and antimicrobial activity greater than 50% than gentamicin (p < 0.05). In E. coli it showed antimicrobial activity less than 50% of the activity shown by Amoxicillin / clavulanic acid and Sulfamethoxazole / Trimethoprim (p > 0.05), and antimicrobial activity greater than 50% than gentamicin (p < 0.05). It was concluded that the dry ethanolic extract at 100% concentration of the root of Dracontium spruceanum (Schott) G.H. Zhu “jergón sacha” showed antimicrobial activity against ATCC strains of Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus, Lima -2024.
Acceso abierto
Anemia y efectividad del tratamiento con suplementos de hierro en población pediátrica del Hospital Carlos Lanfranco la Hoz Puente Piedra - Lima-Peru, 2024
(Universidad Privada Norbert Wiener, 2025-06-03) Cabanillas Rubio, Rocio del Carmen; Campos Pérez, José Rosas; Moscoso Mujica, Gladys Angélica
The research objective was to determine the correlation between anemia and the effectiveness of iron supplement treatment in children under 5 years old at the Carlos Lanfranco La Hoz Hospital, Puente Piedra, Lima-Peru. The methodology involved a retrospective cohort study, descriptive-analytic in nature, utilizing data from the medical records of 100 children under 5 years old diagnosed with anemia and treated with iron supplements at the hospital between January and May 2024. A non-probabilistic convenience sampling method was employed. Data analysis was performed using SPSS version 25 software, with Cramer's V statistical test used to determine the correlation between variables. Results showed a strong correlation between the severity of anemia and treatment effectiveness. While 80% of children with normal anemia showed good effectiveness, this percentage decreased to 52.38% in mild anemia, 56.67% in moderate anemia, and 50% in severe anemia. Furthermore, the proportion of poor effectiveness increased with the severity of anemia (20%, 21.43%, 26.67%, and 38.89% for normal, mild, moderate, and severe anemia, respectively). The conclusion was that a significant correlation exists between anemia and the effectiveness of iron supplement treatment in the pediatric population of the Carlos Lanfranco La Hoz Hospital, Puente Piedra, Lima-Peru, in 2024.
Acceso abierto
Anticonceptivos subcutáneos y calidad de vida en mujeres atendidas en establecimientos de la dirección regional de salud del Callao, Perú, 2023
(Universidad Privada Norbert Wiener, 2025-03-04) Flores Barrionuevo, Deysi Rocio; Flores Pari, Veronica; Moscoso Mujica, Gladys Angélica
Esta investigación tuvo por objetivo determinar la relación entre el uso de anticonceptivos subcutáneos y la calidad de vida en mujeres. Los anticonceptivos subcutáneos son clave en la planificación familiar al ofrecer una opción efectiva y duradera para el control de la fertilidad. Comprender su impacto en la calidad de vida es esencial para brindar una atención integral a la salud reproductiva y sexual de las mujeres. Se empleó un método hipotético-deductivo, con enfoque cuantitativo, bajo el tipo de investigación básica y diseño no experimental de corte transversal, basado en el nivel de investigación correlacional. La muestra consistió en 316 mujeres en edad fértil que recibieron atención en los 45 establecimientos de salud de la DIRESA-Callao, Lima, Perú. Se observó una alta adherencia al anticonceptivo subcutáneo (87.66%), y en cuanto a la calidad de vida, el 94.46% informó una experiencia satisfactoria. Con un nivel de significancia del 0.05, se encontró una relación significativa entre la calidad de vida y las dimensiones de reacciones adversas (p valor de 0.00072<0.05), con los efectos colaterales (p valor de 0.00076<0.05), también se relacionó con la dimensión de adherencia al anticonceptivo subcutáneo (p valor de 0.00068). Finalmente se concluye que se ha demostrado una correlación de intensidad media y significativa (p valor de 0.0488<0.05) entre la calidad de vida y el uso del anticonceptivo subcutáneo, este resultado indica que el uso de anticonceptivos subcutáneos está asociado con la percepción de calidad de vida de las mujeres en este estudio.
Acceso abierto
Características socio - demográficas y condición de trabajo asociadas a preferencia por farmacias en manejo de enfermedades - síntomas de adultos, ENAHO-2023
(Universidad Privada Norbert Wiener, 2025-12-16) Palacios Marcos, Mayra Ibeth; Panta Proaño, Abigail Sara Candelaria; Moscoso Mujica, Gladys Angélica
La presente investigación tuvo como objetivo evaluar la asociación entre las características socio - demográficas y condición de trabajo asociadas a preferencia por farmacias en manejo de enfermedades-síntomas de adultos, con base en los datos de la ENAHO 2023. En la metodología se realizó un estudio observacional, transversal y analítico utilizando los microdatos de la ENAHO 2023. En los resultados se observó que la preferencia por farmacias fue mayor en el sexo masculino (p < 0.001) con una correlación baja, la población de 18 a 29 años presento la mayor elección de farmacias (30,4%, p < 0.001, V Cramer = 0.165) con una relación débil. En el nivel educativo superior con 24.4% y secundaria con 24.3% son los que prefieren farmacias con una relación débil (V Cramer = 0.108), el lugar de residencia que predominó fue urbano con una relación débil (p < 0.001, V Cramer = 0.093). Las condiciones laborales mayores a 40 h prefieren farmacias con 23.3% y una correlación débil (p < 0.001, V Cramer = 0.053), la población formal son los que prefieren farmacias en 22,8% (p < 0.001, V Cramer = 0.018), y la población con ingresos de S/ 9924 a S/ 15474/año con 27.9% son los que prefieren farmacias con una relación débil (p < 0.001, V Cramer = 0.055). Conclusión: Las características socio-demográficas y la condición de trabajo se asoció significativamente con la preferencia por farmacias para el manejo de enfermedades – síntomas en los diferentes parámetros evaluados y con diferentes correlaciones.
Acceso abierto
Conocimiento y uso etnofarmacológico de plantas medicinales en enfermedades comunes del distrito de Molinopampa – Chachapoyas, Amazonas - Perú 2024
(Universidad Privada Norbert Wiener, 2025-04-30) Portocarrero Chavez, Percy; Moscoso Mujica, Gladys Angélica
The present research aimed to identify the relationship between the ethnopharmacological knowledge and use of medicinal plants for common diseases in the district of Molinopampa Chachapoyas, Amazonas-Peru 2024. The study was basic, cross-sectional, correlational in nature, and non-experimental in design; the sample consisted of 327 inhabitants of both sexes from the district of Molinopampa – Chachapoyas, and a questionnaire was used as the instrument. Descriptive analysis was conducted, and to test the hypotheses, the Spearman's Rho correlation coefficient was employed. Regarding the results, it was found that the most common form of using medicinal plants was infusion, accounting for 87.5% compared to 12.5% for all other forms of use combined. Additionally, there was a moderate positive relationship (p<0.05, Rho=0.447) between knowledge of medicinal plants and ethnopharmacological use for common diseases. Furthermore, a moderate positive relationship (p<0.05, Rho=0.591) was found between the identification of medicinal properties and the ethnopharmacological use of medicinal plants, and a strong positive relationship (p<0.05, Rho=0.719) was observed between the transmission of ancestral knowledge and the ethnopharmacological use of medicinal plants for common diseases. It is concluded that there is a very strong positive relationship significance between the ethnopharmacological knowledge of medicinal plants and their ethnopharmacological use for common diseases in the district of Molinopampa-Chachapoyas, Amazonas, 2024.
Acceso abierto
Evaluación de la actividad antianémica de la harina de quinua (Chenopodium quinoa Willd.) variedad negra Collana y kañihua (Chenopodium pallidicaule Aellen) variedad Ramis en ratas anémicas cepa Holtzman, Lima – 2020
(Universidad Privada Norbert Wiener, 2022-06-16) Estrada Huatuco, Zaira Salomé; Estrella Tolentino, Jumira Soledad; Moscoso Mujica, Gladys Angélica
Anemia is a public health problem in Peru and worldwide, with serious cognitive and occupational consequences. The objective of this study was to evaluate the anti-anemic activity of Negra Collana variety quinoa flour (Chenopodium quinoa Willd) and Ramis variety kañihua flour (Chenopodium pallidicaule Aellen) in anemic Holtzman strain rats. The methodology involved obtaining extruded flours of quinoa and kañihua, performing a proximal composition analysis, an acute toxicity test according to the Williams criterion, and a histopathological analysis. Experimental anemia was then induced in rats, and an effective dose was determined. Finally, anti-anemic activity was evaluated for 12 weeks. Results: The flours showed high protein content (22% for quinoa and 16% for kañihua), and both were safe and harmless according to the acute toxicity test. Experimental anemia was successfully induced in rats with hematocrit levels < 33% and hemoglobin < 11 g/dL. The effective dose was 360 mg/kg of quinoa and kañihua flour. In the evaluation of anti-anemic activity, an increase in hematocrit levels of 24.5 ± 0.5% and 22.1 ± 0.3% was observed with quinoa and kañihua flour, respectively, after 12 weeks of treatment (p ≤ 0.05). Conclusion: The oral administration of 360 mg/kg every 24 hours of quinoa and kañihua flour with vitamin C over a 12-week treatment period showed anti-anemic activity in anemic rats.
Acceso abierto
Parasitosis intestinal y estado nutricional en escolares de la institución educativa particular "Jesús de Nazareth" del distrito de Lurigancho – Lima 2024
(Universidad Privada Norbert Wiener, 2025-05-26) Bustamante Campos, Adila; Jara Pizarro, Lisbeth Luisa; Moscoso Mujica, Gladys Angélica
Objective: To determine the relationship between intestinal parasitosis and nutritional status in schoolchildren at the "Jesús de Nazareth" Private Educational Institution in the Lurigancho district - Lima 2024. Methodology: The study was based on a hypothetical-deductive approach with a quantitative focus. It was classified as a basic study. The design was non experimental and cross-sectional, comprising 132 schoolchildren. The technique used was observation, and the instrument was the observation form. Results: It was evidenced 12.9% of the 4th grade, 50.8% for male sex, age of 10 years 15.2%, no association was found with the demographic aspect and anthropometric indicators, clinical indicators of physical inspection type which indicated a relationship with a chi square ,047, in the same way the dietary indicator was related with a chi-square of 0.036, 61.4% of negative cases of parasitosis, a majority percentage of Blastocystis hominis cyst was evidenced 24.5%, 31.8% of children have brittle nails, dull and with little growth, a breakfast diet with 52.3% who consume oats and / or milk and bread, 47% who consume food in the lunchbox (hard-boiled egg, fruit, sandwich and / or infusion), Albendazole 21.2% and paico leaves with a 6.1%. Conclusion: It was determined that intestinal parasitosis in schoolchildren at the "Jesús de Nazareth" Private Educational Institution in the Lurigancho district – Lima 2024 is related to clinical indicators of physical examination, specifically the presence of rough and dry skin (p = 0.047), as well as to breakfast and lunchbox diet (p = 0.036). No significant association was found with age (p = 0.574) or sex (p = 0.500).
Acceso abierto
Prevalencia de hiperglucemia y factores de riesgo en habitantes de “la agrupación de pobladores las terrazas” distrito de Lurín, Lima-Perú, 2024
(Universidad Privada Norbert Wiener, 2024-09-27) Inca Tacsi, Luz Karina; Larico Yto, Edson Washington; Moscoso Mujica, Gladys Angélica
The prevalence of hyperglycemia and its associated factors has been a persistent concern in the field of public health on a global scale. For this reason, the objective of this study is to determine the relationship between the prevalence of hyperglycemia and risk factors in the inhabitants of the Las Terrazas community in the Lurín district. Methodology: hypothetical-deductive method, quantitative approach, basic type, non-experimental design, cross-sectional and correlational level, survey technique, and questionnaire instrument applied to 108 people. Results: The majority age group was 18 to 29 years old (42.6%), with women predominating at 73.1%. Furthermore, the relationship between the prevalence of hyperglycemia and sociodemographic factors showed that the majority of the population earns minimum wage (54.6%) and is composed of women." 73.1% and showed no positive relationship. In the relationship between the prevalence of hyperglycemia and comorbidities such as hypertension, significant (40%) and positive associations were shown (x2 = 8.120, p = 0.004), and obesity showed a significant (42.9%) and positive association (x2 = 13.715, p = 0.000); however, diabetic retinopathy, kidney disease (nephropathy), and diabetic neuropathy showed a very low frequency, less than 7%, and showed no positive or significant relationship. In the relationship between the prevalence of hyperglycemia and lifestyle, it was shown that the population is non-smoking (90.7%), does not exercise (63%), and their main diet consists of carbohydrates, sweetened processed beverages, processed foods, and fried foods, and showed no positive or significant relationship; however, the Habits such as the consumption of alcoholic beverages showed a certain tendency toward hyperglycemia approaching significance (p=0.091). The relationship between hyperglycemia and family history did not show a positive or significant relationship. The relationship between the prevalence of hyperglycemia and anthropometric measurements showed a normal BMI in 38%, followed by overweight in 36.1%, with a waist circumference at risk in 54.6%, which did not show a positive or significant relationship. However, some differences were observed between hyperglycemia, overweight, and waist circumference with low p-values. Therefore, the null hypothesis (H0) of specific hypotheses 1, 3, 4, and 5 was confirmed because the study population did not present hyperglycemia, with normal blood glucose values ≤ 99 mg/dL representing 92.6% of the population. Furthermore, It was observed that the 50-59 age group presented a higher proportion of hyperglycemia at 23.1%. Conclusion: Of the five variables evaluated, variable two, in most comorbidities, showed a significant relationship with hyperglycemia, unlike the other variables of the risk factors in the inhabitants of the Las Terrazas community in the Lurín district, 2024.
Acceso abierto
Prevalencia del uso de hipolipemiantes de pacientes que acuden a la Botica Melchorita del distrito de Chincha, enero - diciembre, 2022
(Universidad Privada Norbert Wiener, 2025-11-25) Santos Chamorro, Renzo Gastón; Moscoso Mujica, Gladys Angélica
Objective: To determine the prevalence of lipid-lowering use in patients attending the Manchuria pharmacy in the Chicha district, January - December 2022. Methodology. Applied cross-sectional descriptive method that opted for a data collection form as an instrument. The total population studied consisted of 85,383 sales receipts, processed and statistically analyzed. Results. It was observed that the highest percentage of lipid-lowering use was recorded in February 2022, with a point prevalence of 3.5% (0.035). 9.1% of lipid-lowering use was reported in patients who attended the pharmacy between January and March; 85.3% purchased fewer than 10 units of lipid lowering drugs; The most frequently requested lipid-lowering agent was atorvastatin 20 mg, representing 47.9% of the prescriptions. 64.2% of prescriptions included concomitant medications with lipid-lowering agents exceeding 5 units of other dosage forms in patients attending the pharmacy. Conclusion: The point prevalence of lipid-lowering agent use was 3.5% among patients attending during the summer.
Acceso abierto
Reacciones adversas y frecuencia relacionadas al uso de anticonceptivos hormonales inyectables de usuarios de boticas del AAHH San Genaro Chorrillos-Lima Metropolitana, 2023
(Universidad Privada Norbert Wiener, 2025-03-06) Aliaga Gonzales, Franklin; Gómez Ramos, Alexandra; Moscoso Mujica, Gladys Angélica
The objective of the study was to evaluate the correlation between the use of injectable hormonal contraceptives and adverse reactions in users of AAHH San Genaro Chorrillos - Metropolitan Lima, 2023. A hypothetical deductive method was used with a basic and observational quantitative approach. Regarding the design, it was a non-experimental, correlational study with a cross sectional approach. The sample was 385 people, who were randomly chosen in the different pharmacies in the sector under study, applying the inclusion and exclusion criteria. An online questionnaire was used, the answers to which were tabulated in Excel and finally analyzed with IBM SPSS version 26. Results: most of the users were between 26 and 35 years old, Mesigyna was the most used contraceptive (43.1%), followed by Soluna (20.5%) and Nofertyl (15.5%). A significant correlation was shown between some dimensions of the use of injectable hormonal contraceptives and adverse reactions in users of pharmacies at the AAHH San Genaro Chorrillos Lima Metropolitana, 2023. As in the adverse reaction of gastrointestinal disorders with the diarrhea dimension (p = 0.008; Cramer's V = 0.150), weight change (p = 0.038; Cramer's V = 0.132), and in mastalgia both dimensions were significant (p < 0.05); thus, the breast tension dimension showed p = 0.015 and weak intensity Cramer's V = 0.143; similarly, the breast tenderness dimension showed p = 0.005 and weak intensity (Cramer's V = 0.156). The use of injectable hormonal contraceptives with vaginal infections, menstrual disorders, emotional depression, and headache did not show a significant correlation (p> 0.05). Conclusion: There was a correlation between the use of injectable hormonal contraceptives and adverse reactions, with Mesigyna being the most commonly used hormonal contraceptive, which frequently and very frequently presented the majority of adverse reactions across several dimensions.
Acceso abierto
Uso de chancapiedra (Phyllanthus niruri) y enfermedades renales en consumidores del mercado mayorista de Santa Anita, Lima, 2025
(Universidad Privada Norbert Wiener, 2026-06-04) Lopez Tolentino Diego; Zumaeta Perez, Franklin Armando; Moscoso Mujica, Gladys Angélica
La presente investigación tuvo como objetivo general determinar la relación existente entre el uso de Phyllanthus niruri (Chancapiedra) y la presencia de enfermedades renales en consumidores del Mercado Mayorista de Santa Anita, Lima, 2025. Es un estudio básico, cuantitativo, transversal, no experimental y de nivel correlacional. Enmarcado en un diseño no experimental de nivel correlacional. La población muestral estuvo constituida por 155 sujetos mayores de edad, de ambos sexos, seleccionados mediante muestreo probabilístico. Se uso un cuestionario estructurado para recoger datos sobre hábitos de consumo, frecuencia, forma de preparación (infusión, decocción, tintura), partes de la planta empleadas y antecedentes renales. El análisis estadístico incluyó estadística descriptiva y la prueba Rho de Spearman (p < 0,05). Los resultados evidenciaron el 40,0% de participantes entre 18-40 años, el 78,1% con instrucción superior y el 56,2% trabajadores dependientes. La comorbilidad más frecuente fue el sobrepeso (77,5%). Respecto al uso, el 55,5% no consumía diariamente, predominando infusión (34,8% "algunas veces"), decocción y tintura. El análisis inferencial, se encontró relación positiva fuerte y significativa entre uso de Phyllanthus niruri y autorreporte de daño renal (Rho = 0,724; p = 0,000), con correlaciones moderadas en frecuencia (Rho = 0,567; p = 0,000) y preparación (Rho = 0,660; p = 0,000). En conclusión, hay relación significativa en uso de Phyllanthus niruri y presencia de enfermedades renales, evidenciando su rol en prácticas populares de salud. Se recomienda promover uso responsable con supervisión profesional, estandarización de preparados y mayor investigación científica sobre eficacia y seguridad.