Examinando por Autor "Pinedo Panduro, Lauro Sócrates"

Mostrando 1 - 11 de 11

Acceso abierto
Aplicación de pruebas de estabilidad acelerada para conocer la fecha de vencimiento de la Crema Facial Bioactiva en el laboratorio Brillant, Lima 2023
(Universidad Privada Norbert Wiener, 2024-10-02) Atencio Alvites, Violeta Maria; Flores Ojeda, Yoysi Romina; Pinedo Panduro, Lauro Sócrates
This research applied accelerated stability tests to the Bioactive Facial Cream. Objective: To determine the estimated expiration date for the Bioactive Facial Cream after subjecting it to accelerated stability tests at the Brillant laboratory, Lima 2023. Methodology: Deductive method, quantitative approach, applied research type, experimental design, and cross-sectional study; the research level is explanatory; the organoleptic, physicochemical, and microbiological parameters were evaluated after subjecting the Bioactive Facial Cream to the stress aging method using different temperatures such as refrigeration, ambient, and oven for 0, 1, 7, 15, 30, 60, and 90 days. Results: The application of the accelerated stability tests performed on the Bioactive Facial Cream demonstrates that over time the organoleptic parameters underwent a modification The physicochemical parameters showed slight but non-determining variation, and the microbiological parameters showed an absence of total aerobic mesophilic microorganisms, fungi, yeasts, and pathogens. Conclusion: The accelerated stability tests performed on the Bioactive Facial Cream allowed for the calculation of a shelf life of 14 months; this determined the expiration date, which should be confirmed with long-term stability testing.
Acceso abierto
Cumplimiento de implementación de las buenas prácticas de oficina farmacéutica en boticas del distrito de Lince - Lima, octubre - diciembre 2023
(Universidad Privada Norbert Wiener, 2024-09-20) Avila Castro, Yanira Andrea; Trinidad Peña, Diana Liz; Pinedo Panduro, Lauro Sócrates
Esta investigación se desarrolló con el objetivo de reconocer el cumplimiento de implementación de Buenas prácticas de Oficina Farmacéutica en Boticas del Distrito de Lince - Lima, octubre - diciembre 2023. En nuestra tesis se utilizó el método deductivo, enfoque cuantitativo, de tipo básico, diseño no experimental, corte transversal y prospectiva. La población estuvo conformada por 70 boticas en el distrito de Lince, se utilizó como instrumento una guía de observación que contenía 26 ítems, los que estuvieron distribuidos en 6 dimensiones. En los resultados se obtuvo que el 47,5% presentaba una implementación óptima en la dimensión personal, en la documentación e infraestructura 49,2% era óptimo, en las buenas prácticas de farmacovigilancia el 32,8% fue óptimo. Como conclusión se obtuvo que el 13,1% presento un cumplimiento “óptimo; el 55,7% en proceso y el 31,1% deficiente con respecto a la implementación de las Buenas prácticas de oficina farmacéutica.
Acceso abierto
Cumplimiento de las buenas prácticas de almacenamiento en una cadena de boticas en la ciudad de Trujillo, junio-agosto 2022
(Universidad Privada Norbert Wiener, 2024-10-22) Hoyos Fernández, María Yesenia; Pinedo Panduro, Lauro Sócrates
The objective of the study was to determine compliance with good storage practices in a drugstore chain in the city of Trujillo, June-August 2022.Methodology: Deductive method, quantitative approach, basic type, descriptive level, non-experimental design, cross section retrospective. The technique used was observation with the observation guide instrument, the population and sample consisted of 15 pharmacies from the pharmacies chain Peru, the sampling has been non-probabilistic of an intentional type. Whose results show in terms of infrastructure compliance with 66,6%, in internal organization compliance is medium with 83,3%, in personnel compliance with 55,6 % and management and distribution technique is high compliance with 66,6%. Conclusion it is determined that compliance with good storage practices in a chain of pharmacies in the city of Trujillo, June August 2022 is average compliance with 66,7%.
Acceso abierto
Educación farmacéutica y su relación con el uso racional del medicamento en la botica "BIOSALUD" Ventanilla 2023
(Universidad Privada Norbert Wiener, 2024-07-10) Meza Peña, Roamir; Pinedo Panduro, Lauro Sócrates
The general objective assigned to this research was: To determine the relationship between pharmaceutical education and the rational use of medications in patients of the pharmacy "BIOSALUD" 2023. A hypothetical-deductive method was employed, with a quantitative approach, basic type, non-experimental design, correlational level, and cross-sectional scope. The population consisted of 151 patients, with a census sample and saturation sampling method. Data collection was conducted through surveys based on a questionnaire of 18 questions: 9 for variable I with 5 possible responses and 9 for variable II with 4 possible responses. The results showed a moderate positive correlation between pharmaceutical education and the rational use of medications, supported by a significant p-value (p<0.05) and a Spearman's rho correlation of 0.552. An even gender distribution was observed, with 53% female and 47% male participants. It was noted that the pharmaceutical educator provided quality information, empathy, and communication while allowing patient participation. This resulted in compliance with guidelines and recommendations, enabling patients to manage side effects and use medications in an informed manner. These findings suggest that pharmaceutical education is partially related to the rational use of medications in patients who visit the pharmacy "BIOSALUD" Ventanilla 2023. In other words, continuous pharmaceutical education proportionally increases the correct use of medications.
Acceso abierto
Eficacia del ácido peracético para la desinfección in situ en el área de envasado de formas farmacéuticas estériles en un laboratorio de industria farmacéutica, Lima, septiembre – 2019 a septiembre – 2020
(Universidad Privada Norbert Wiener, 2021-10-22) Torres Maccanascca, Karina; Cardoza Sánchez, Verónica; Pinedo Panduro, Lauro Sócrates
The objective of this study was to demonstrate the efficacy of peracetic acid for the in-situ disinfection of equipment in the 'sterile packaging area 2' for pharmaceutical forms within a pharmaceutical industry laboratory. An experimental, quantitative, and cross-sectional study was conducted using the dilution-neutralization method to determine the efficacy of peracetic acid at concentrations of 0.6%, 1.2%, and 1.8% with contact times of 5, 10, and 15 minutes. For in-situ antimicrobial activity, the contact plate method was used for surfaces and the swab method was used for equipment. Statistical analysis was performed using the Kolmogorov-Smirnov and Kruskal-Wallis methods. It was found that peracetic acid at a 1.2% concentration with a 5-minute contact time showed bacterial and fungal growth, unlike the 10- and 15-minute contact times, where it satisfactorily eliminated them. At the 1.8% concentration, no growth of bacteria or fungi was observed for any exposure time. The determination of antimicrobial activity on surfaces and equipment showed a 99.999% reduction.
Acceso abierto
Gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed Corporation, 2024
(Universidad Privada Norbert Wiener, 2025-05-28) Cáceres Barzola, Stefany Mayra; Ynfantes Almeyda, Sonia Pilar; Pinedo Panduro, Lauro Sócrates
Se tuvo como objetivo: Determinar la relación entre la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed CORPORATION, 2024. Metodología: Se trabajó con una metodología cuantitativa, de diseño observacional, de corte transversal y nivel correlacional. Población y muestra: Fue integrada por 74 trabajadores en el laboratorio farmacéutico Pharmed CORPORATION de las áreas de Control de calidad, producción y almacén, como técnica de estudio se aplicó la encuesta a través del uso de dos cuestionarios, cabe recalcar que dichos instrumentos son validados y confiables. Resultados: Se observó que al correlacionar la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico, se encontró que del grupo que presenta una gestión de la cadena de suministro mala, manifiesta una productividad baja en un 14,9% en su mayoría. Los que presentan una gestión de la cadena de suministro regular, manifiestan una productividad media en un 27,0% en su mayoría. Por último, aquellos que presentan una gestión de la cadena de suministro buena, manifiestan una productividad alta en un 21,6% en su mayoría. Se concluyó que hay relación directa entre la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed CORPORATION, 2024, con una significancia del 0.000 menor al 0.01.
Acceso abierto
Incidencias de errores relacionados al uso de dispositivos médicos en el Hospital Hipólito Unanue de enero a diciembre del 2023
(Universidad Privada Norbert Wiener, 2025-08-12) Faustor Andazabal, Daniel; Pinedo Panduro, Lauro Sócrates
Identifying incidents related to the misuse of medical devices is essential for anticipating and evaluating patient conditions, improving hospital stay, and ensuring adequate recovery. Although medical devices are crucial in healthcare, their misuse may lead to infections or harm, negatively affecting patient safety. This study, entitled: "Incidents of errors related to the use of medical devices at the Hipólito Unanue Hospital from January to December 2023", aimed to analyze these incidents during the indicated period. The research used an inductive method, with a quantitative approach and an applied type of study. The study population consisted of 90 reported notifications of medical device errors. A non-probabilistic convenience sampling method was used. The data collection technique was descriptive, using an observation form that recorded details about the types of devices, error frequency, and risk level. The results revealed that a significant number of notifications were associated with infusion pumps and monitoring equipment. Most incidents were classified as moderate, highlighting the need for preventive strategies. In conclusion, it is essential to strengthen technovigilance systems and implement training programs to ensure the correct use of medical devices and protect patient safety.
Acceso abierto
Manejo del dolor crónico no oncológico con relación a síntomas depresivos en adultos mayores de 40 años atendidos en tres boticas del distrito de Comas, 2023
(Universidad Privada Norbert Wiener, 2024-10-23) Ponte Pino, Cruzlee; Rojas Cirilo, Jose Luis; Pinedo Panduro, Lauro Sócrates
The objective of the research was to analyze the relationship between the management of chronic non-cancer pain and depressive symptoms in adults over 40 years of age. Method. The research was basic type, hypothetical deductive method, non-experimental design, quantitative approach, cross section, correlational scope, 183 people made up the sample, simple random probabilistic sampling, data was collected with a questionnaire survey, the hypothesis was contrasted with test of Spearman's Rho. Results. Of the total respondents, 55.7% were male, 55.4% were between 40-50 years old. In non-oncological chronic painful pathologies, between 34.4% and 56.8% presented back pain, shoulder and/or neck pain; Chronic headaches and osteoarticular pain. In pain pharmacotherapy, between 42.6% and 51.4% consumed non-steroidal antiinflammatory drugs; paracetamol and tramadol. In terms of pain pharmacotherapy, between 36.6% and 56.8% the analgesic decreased pain and improved stress. In affective symptoms of depression, 71% showed little interest in enjoying things; 47% discouraged feelings; 41.5% had difficulty sleeping, in behavioral symptoms, 26.2% indicated feeling tired and 35.5% had difficulty concentrating, in everyday problems, 34.4% found it very difficult to do their work. There was a relationship between the management of chronic non-cancer pain and depressive symptoms. Conclusion. There is a low positive relationship between the management of chronic nononcological pain and depressive symptoms in adults over 40 years of age attended in three pharmacies in the district of Comas 2023.
Acceso abierto
Niveles de hormona estimulante de la tiroides en relación con el índice de masa corporal en personas de una institución cristiana de Villa María del Triunfo, Lima 2022
(Universidad Privada Norbert Wiener, 2023-07-20) Soto Chihua, Andrea Paola; Pinedo Panduro, Lauro Sócrates
The Body Mass Index (BMI) allows for determining the presence of overweight and obesity in individuals, while the Thyroid-Stimulating Hormone (TSH) is a thyroid hormone that contributes to proper metabolic functioning in the body. Objective: To determine the relationship between TSH levels and BMI in individuals from a Christian institution in Villa María del Triunfo, Lima, 2022. Method: The deductive method was used, with a quantitative approach, basic type, non-experimental, correlational, cross-sectional, and prospective design. The sample consisted of 100 individuals, and the survey technique was employed, with a questionnaire as the instrument. Additionally, weight and height were measured, and blood analyses were conducted to determine TSH levels using the immunochromatography assay. Results: A significant relationship was demonstrated between diet and TSH levels, and a weak positive relationship (Rho= +0.228) was found between BMI and TSH levels in individuals with TSH values within the normal range. Conclusion: It was determined that Thyroid-Stimulating Hormone levels were related to Body Mass Index in individuals from a Christian institution in Villa María del Triunfo
Acceso abierto
Reducción del tiempo de analisis del excipiente farmacéutico lactosa monohidrato en laboratorios AC Farma S.A., distrito de Ate, 2019–2022
(Universidad Privada Norbert Wiener, 2024-02-28) Pacora Astorga, Monica Pamela; Pinedo Panduro, Lauro Sócrates
Objective: To establish whether it is feasible to implement a reduction in the analysis time of the pharmaceutical excipient lactose monohydrate in a pharmaceutical laboratory during the period 2019–2022. Method: Inductive method through data collection, descriptive level, quantitative approach, basic type, non-experimental design, cross-sectional. The variable corresponds to the pharmaceutical excipient lactose monohydrate, whose dimensions were validated by three specialists. The population consisted of 34 batches of the excipient entered between 2019 and 2022. The applied techniques were survey and documentary analysis, using a questionnaire and a data capture sheet as instruments. Documentary evaluation was carried out to verify compliance with technical standards, personnel qualification, and the existence of an implemented quality system. Results: The documentary evaluation verified that both manufacturer and supplier complied with international standards, with results of 91.3% and 81.11%, respectively. Evaluation and monitoring of manufacturer and supplier performance yielded an average of 98.5% across the four years assessed, meeting the established parameters of 80% to 100%. Analytical results from both the laboratory and the supplier were within specifications, with approved outcomes. Conclusion: It was concluded that the analysis time of the pharmaceutical excipient lactose monohydrate can be reduced from five days to one day, since seven out of the nine tests established by the international USP standard can be omitted by relying on the manufacturer’s results.
Acceso abierto
Síndrome de burnout en el personal que labora en farmacias y boticas del distrito de Villa María del Triunfo. Lima 2022
(Universidad Privada Norbert Wiener, 2023-07-20) Ccahuaya Laura, Yanet Dina; Gabriel Rocha, Flora Simona; Pinedo Panduro, Lauro Sócrates
The present research aims to determine Burnout Syndrome (BS) among personnel working in pharmacies and drugstores in the district of Villa María del Triunfo, Lima, 2022. The research type was descriptive and cross-sectional, with a sample consisting of 224 workers, including technical staff and professional pharmaceutical chemists. Results indicate that 51.3% exhibit a high level of Burnout Syndrome in the emotional exhaustion dimension; 61.2% show a high level of Burnout Syndrome in the depersonalization dimension; 39.3% exhibit a low level of Burnout Syndrome in the personal accomplishment dimension. Among workers aged 18 to 28 years, 22.3% exhibit a moderate level of BS; 10.3% of married workers exhibit a moderate level of BS; 33.5% of female workers exhibit a moderate level of BS, and 25.4% consider their work environment unpleasant and exhibit a moderate level of BS. This thesis concludes that 47.3% of personnel working in pharmacies and drugstores in Villa María del Triunfo exhibit a moderate level of Burnout Syndrome.