Farmacia y Bioquímica

URI permanente para esta comunidadhttps://hdl.handle.net/20.500.13053/33

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Accesibilidad de los medicamentos esenciales genéricos en oficinas farmacéuticas del distrito de Comas, Lima 2022
(Universidad Privada Norbert Wiener, 2023-09-21) Guerrero Sifuentes, Abel Eduardo; Ramos Jaco, Antonio Guillermo
Currently, the Peruvian government has been implementing a series of strategies in the public health sector to ensure the optimal availability of essential medicines, from the first level of care to specialized institutes, aiming for full health coverage for the population. Essential generic medicines are of high priority to ensure public access as a public health right. The objective of this research was to evaluate the accessibility of essential generic medicines in terms of price and availability in pharmaceutical offices in the district of Comas, Lima, 2022. This is a study with a deductive-quantitative-descriptive methodology. The technique used was through data recording, validated by three experts in the field. The instrument applied was a data collection form, which gathered information on the availability and prices of 47 medicines listed as essential generic medicines, approved by Ministerial Resolution N°302-2020-MINSA, in a total of 73 pharmacies in the district of Comas from June to November 2022. The findings revealed a 91% availability of the entire list of medicines, with individual availability reaching 100% only for Captopril, Metformin, Naproxen, and Paracetamol solution. Regarding prices, variations ranged from 10% to 55%. Finally, it was concluded that the full list of essential generic medicines was not entirely available in the pharmacies in the district of Comas, and price variations showed up to a 55% coefficient of variation (CV).
Acceso abierto
Accesibilidad de los medicamentos esenciales genéricos en oficinas farmacéuticas del distrito de San Juan de Lurigancho. Lima 2022
(Universidad Privada Norbert Wiener, 2022-11-10) Estrada Zanini, Deyda Karett; Caldas Herrera, Emma
In Peru, essential generic medicines are necessary and fundamental for the population to access as a public health right. The objective of this research was to evaluate the accessibility of essential generic medicines in terms of price and availability in pharmaceutical offices in the district of San Juan de Lurigancho, Lima, 2022. This is an applied study with a quantitative approach and a cross-sectional observational design. The instrument used was a data collection form with the observational technique. Results: A 91% availability was found for the entire list of medicines, and a 100% availability was determined individually for Captopril, Metformin, Naproxen, and Paracetamol solution. Regarding prices, a variation ranging from 10% to 55% was found. Conclusion: The availability of the full list of essential generic medicines was not entirely met in the pharmacies of San Juan de Lurigancho, while price variation showed a coefficient of up to 55%.
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Aceptación de medicamentos genéricos en usuarios que acuden a la botica BTP – distrito de Chaclacayo – Lima provincias, 2022
(Universidad Privada Norbert Wiener, 2023-04-28) Arias Ramos, Rosa Edith; Avila Sánchez, Rose Mary; Muñoz Jáuregui, Manuel Jesús
The general objective was to determine the level of acceptance of generic medications among users who visit the BTP pharmacy in the district of Chaclacayo, Lima provinces, 2022. Methodology: The research had a quantitative approach, basic type, with a descriptive level, non-experimental design, and cross-sectional scope. The study population consisted of 1,600 surveyed users, and the sample was probabilistic, resulting in 310 users. These users were evaluated using a research instrument validated by a panel of three experts on the topic and reliability measured through Cronbach's alpha, which had a good value (α = 0.868). Results: Data tabulation revealed that the level of acceptance of generic medications among users visiting the BTP pharmacy in Chaclacayo, Lima provinces, in 2022 was expressed as medium (84.8%). Similarly, the information level was medium (70%), the consumption level was medium (72.3%), the safety level was low (50%), and the access level was medium (60.6%). Conclusion: The level of acceptance of generic medications among users was 84.8%.
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Aceptación y disponibilidad de medicamentos genéricos en usuarios de la botica Divino Niño Jesús de Mariscal Cáceres San Juan de Lurigancho enero 2022
(Universidad Privada Norbert Wiener, 2024-07-04) Ortiz Torres, Maria Isabel; Yurivilca Salazar, Rocio Del Pilar; Ramos Jaco, Antonio Guillermo
Objetivo: Determinar el nivel de aceptación y disponibilidad de los medicamentos genéricos en los usuarios de la botica Divino niño Jesús de Mariscal Cáceres San Juan De Lurigancho. Metodología: Enfoque cuantitativo, tipo de investigación aplicada, diseño no experimental con método deductivo, caracterizado por un enfoque observacional y transversal. Población, 450 usuarios, Muestra, 207, muestreo probabilístico aleatorio simple. Técnica la encuesta la cual fue de modo presencial. El instrumento aplicado fue un cuestionario. Se utilizó el software estadístico Office Excel para realizar el análisis de datos. Resultado: en relación a la aceptación y disponibilidad de medicamentos genéricos los encuestados indican que la aceptación de medicamentos genéricos es mayoritariamente en un nivel regular (49,76%), siendo que el 7,25% no los acepta. En cuanto al grado de aceptación, el 59,76% tiene un nivel regular, el 26,57% tiene un nivel bueno y sólo el 12,56% tiene un nivel malo. En cuanto a la frecuencia de aceptación, el 50.24% tiene un nivel regular, el 34.30% tiene un nivel bueno y solo el 15.46% tiene un nivel malo. En cuanto a disponibilidad y accesibilidad, el 29,95% tiene un nivel bueno en la dimensión consumo, el 54,11% tiene un nivel regular y el 15,94% tiene un nivel malo. Conclusión: existe un apreciables aceptación y disponibilidad de medicamentos genéricos en los usuarios de la botica divino niño Jesús de Mariscal Cáceres San Juan de Lurigancho-periodo enero 2022”.
Acceso abierto
Actitud de las personas con afecciones gastrointestinales en el uso de plantas medicinales como terapia alternativa que acuden al mercado Real Plaza Vitarte APROMEC – Ate, 2023
(Universidad Privada Norbert Wiener, 2023-09-22) Barzola Lopez, Ricardo Jack; Lovera Llamoja, Roxana Patricia; Félix Véliz, Luis Miguel Visitación
The objective of this research was to “Determine the attitude of individuals with gastrointestinal conditions towards the use of medicinal plants as an alternative therapy.” The methodology was based on a deductive method with a quantitative approach, basic type, descriptive level, non-experimental design, and cross-sectional approach. The sample consisted of 267 people. A survey and a questionnaire were used as the technique and instrument, respectively. The data obtained were entered and processed using Excel and SPSS software, achieving a good reliability score of 0.810. The results showed that 77.9% of the respondents were between the ages of 31 and 59 years, 73.4% were female, and 60.3% had secondary education. The most consumed plants were chamomile (26.97%), followed by muña (19.10%), mint (13.11%), and lemongrass (11.61%). Regarding attitudes, 89.5% of the participants exhibited a positive attitude, and 10.5% had a neutral attitude. Conclusion: It was determined that individuals with gastrointestinal conditions who use medicinal plants as an alternative treatment have a positive attitude. Additionally, the various dimensions analyzed showed positive results, except for the dimensions of safety and efficacy, where the attitude was neutral.
Acceso abierto
Actitudes frente a la vacunación COVID-19 en pobladores del caserío Valle Hermoso del distrito de Monsefú – provincia Chiclayo, 2022
(Universidad Privada Norbert Wiener, 2022-06-09) Lluén Gamarra, Carolina Andrea; Aguila Manrique, Iris Aurelia; Oyarce Alvarado, Elmer
The research, titled "Attitudes Toward COVID-19 Vaccination Among Residents of the Valle Hermoso Hamlet in the Monsefú District – Chiclayo Province, 2022," had the Objective of determining the relationship between the attitudes of the population of the Valle Hermoso hamlet and COVID-19 vaccination in the Monsefú district, Chiclayo province, in 2022. Methodology: This was a hypothetical-deductive study with a quantitative approach, a cross-sectional type, basic research, correlational study, and a non-experimental design. The sample consisted of 188 residents, and the instrument used was a questionnaire. Data processing was performed using the SPSS version 25 statistical program. Results: A relationship exists between overall attitudes and COVID-19 vaccination, with the value rs=0.560 indicating a moderate correlation. A relationship exists between experiences and COVID-19 vaccination, with the value rs=0.200 indicating a weak correlation. A relationship exists between emotions and COVID-19 vaccination, with the value rs=0.390 indicating a moderate correlation. A relationship exists between valuation and COVID-19 vaccination, with the value rs=0.502 indicating a moderate correlation. A relationship exists between risk perception and COVID-19 vaccination, with the value rs=0.556 indicating a moderate correlation. A relationship exists between knowledge and COVID-19 vaccination, with the value rs=0.491 indicating a moderate correlation.
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Actividad antidepresiva del extracto etanólico de las hojas de Manihot esculenta Cranz “yuca” en ratones
(Universidad Privada Norbert Wiener, 2023-02-20) Gallardo Delgado, Shirley Jasmin; Justil Guerrero, Hugo Jesús
Depression is a mood disorder characterized by feelings of sadness, with episodes lasting weeks or months, often leading to suicidal thoughts. According to the "WHO," this disease is very common worldwide, affecting more than 280 million people. Over half of those affected do not receive treatment due to a lack of resources or misdiagnosis. Objective: The present study aimed to evaluate the antidepressant activity of the ethanolic extract of Manihot esculenta Cranz leaves ("cassava") in mice. Methodology: The study was experimental and quantitative. The leaves were collected in the district of La Merced, Province of Chanchamayo, Department of Junín. Secondary metabolites of the ethanolic extract were identified. The antidepressant activity (AAD) was evaluated using the forced swimming test in 30 albino mice at doses of 50, 100, and 200 mg/kg of the ethanolic extract administered orally, compared to fluoxetine at 20 mg/kg. Immobility time, swimming time, and climbing time were measured over 15 minutes. Results: The lowest average immobility time was observed in the group treated with the ethanolic extract at 200 mg/kg, with 13.5 seconds, while the control group showed a significantly higher immobility time of 104.2 seconds. The swimming time was highest in the group treated with 200 mg/kg of the ethanolic extract, averaging 177.5 seconds, as was the climbing time, averaging 49.0 seconds. Conclusion: The ethanolic extract at a concentration of 200 mg/kg has antidepressant activity comparable to fluoxetine.
Acceso abierto
Actividad antifúngica del extracto de propóleo frente a Candida albicans de pacientes con candidiasis vulvovaginal en el año 2021
(Universidad Privada Norbert Wiener, 2022-06-15) Rodríguez Loyola, Gina Andrea; Collanque Pinto, Jesús Daniel
The general objective of this research was to evaluate the antifungal activity of propolis extract against Candida albicans from patients with vulvovaginal candidiasis in 2021. The research used a quantitative approach with an experimental design. The population consisted of C. albicans strains isolated from patients with vulvovaginal candidiasis admitted to the Gynecology Service of a Private Clinic in Lima. A total of 34 strains were chosen (17 C. albicans strains from acute cases and 8 from recurrent cases) and were treated with propolis extract and fluconazole, with three repetitions, resulting in 102 experimental units. The antifungal susceptibility test was performed using the disk diffusion method with a single concentration of propolis extract and fluconazole as the positive control. Results: The propolis extract, like fluconazole, inhibited all C. albicans strains. However, the effect of fluconazole was significantly greater than that of the research product. Conclusion: The propolis extract does show antifungal activity against C. albicans.
Acceso abierto
Actividad antiinflamatoria de un ungüento formulado a partir del extracto hidroetanólico de las hojas de Cissus gongylodes Burch. ex Baker “Suelda Suelda” en ratas albinas
(Universidad Privada Norbert Wiener, 2024-10-14) Esteban Paucar, Steffany Wengyi; Romero Mendoza, Winnie Ashley; Dueñas Zurita, Julia
El objetivo fue determinar la actividad antiinflamatoria del ungüento formulado a partir del extracto hidroetanólico de las hojas de Cissus gongylodes Burch ex Baker “Suelda Suelda” (UEHCG) en ratas albinas. Métodos. El estudio tuvo diseño experimental, tipo aplicado, corte longitudinal, enfoque cuantitativo, alcance explicativo, muestreo aleatorio simple, la planta fue recolectada en distrito Mazamani, provincia Satipo, departamento Junín, se empleó 30 ratas albinas cepa Holtzman, se formó 5 grupos y administró tratamientos vía tópico, grupo 1: ungüento base, grupo 2: diclofenaco gel 1%, grupo 3: UEHCG 1%, grupo 4: UEHCG 3%, grupo 5: UEHCG 5%, la inflamación fue inducida con carragenina 1% en NaCl 0,1 mL en aponeurosis plantar de la rata, el edema fue medido con Vernier a las 0, 1, 3, 6 y 8 horas, al extracto se realizó prueba de solubilidad y perfil fitoquímico cualitativo. Resultados. El extracto fue soluble en metanol, agua y etanol, se identificó compuestos fenólicos, flavonoides, taninos, alcaloides y leucoantocianidinas. El UEHCG 5% mostró efecto antiinflamatorio significante (p<0,05) a las 6 y 8 horas con inhibición de la inflamación de 48% y 74% respectivamente, el diclofenaco 1% inhibió la inflamación en 45% a las 8 horas y fue significante (p<0,05) comparado con el grupo control. Conclusión. El UEHCG 5% si tiene actividad antiinflamatoria significante a las 6 y 8 horas de tratamiento en ratas albinas con 74% de inhibición de la inflamación.
Acceso abierto
Actividad repelente in vitro de los aceites esenciales de Syzygium aromaticum "clavo de olor" y Cinnamomum verum "canela" sobre Aedes Aegypti
(Universidad Privada Norbert Wiener, 2022-05-13) Abanto Rojas, Rita Norma; Alvarez Torres, Eugenia Albertina; Chávez Flores, Juana Elvira
The objective of this study was to evaluate the in vitro repellent activity of the essential oils of Syzygium aromaticum ('clove') and Cinnamomum verum ('cinnamon') and a 50/50 v/v combination of both oils on Aedes aegypti. The essential oils were obtained by steam distillation, and the area preference method was used to evaluate repellent activity. The repellent activity of the essential oils and the 50/50 v/v combination was evaluated on the Aedes aegypti Rockefeller strain at various concentrations (0.2%, 0.1%, 0.05%, 0.03%, and 0.01%). N,N-diethyl-3-methylbenzamide (DEET) at 15% was used as a positive control, and acetone was used as a negative control. It was concluded that the essential oils of Syzygium aromaticum, Cinnamomum verum, and their combination do have in vitro repellent activity on Aedes aegypti. The minimum repellent concentration was 0.03%, and the repellency time was five (5) hours at concentrations of 0.05%, 0.1%, and 0.2%. Furthermore, the in vitro repellency level was found to be between class IV and V (using the Talukder and Howes rating) at the 0.05%, 0.1%, and 0.2% concentrations from the 1st to the 5th hour.
Acceso abierto
Adherencia a la terapia farmacológica y sus factores asociados en pacientes con tuberculosis del programa de TBC en un centro de salud de Lima Metropolitana, 2021
(Universidad Privada Norbert Wiener, 2022-01-17) Palacin Custodio, Maritza Lucia; Ñañez del Pino, Daniel
Currently, poor adherence to treatment for chronic diseases is a global problem of alarming magnitude. In Peru, where public hospitals are often precarious and medicines are scarce, medical staff are redoubling their efforts to keep patients on track with their treatments. This research aims to determine the relationship between adherence to pharmacological therapy and associated factors in patients with tuberculosis from the TBC program at a health center in Metropolitan Lima in 2021. The research methodology is based on a quantitative approach, with a basic study type, a correlational level, and a non-experimental, cross-sectional design. The population consists of 300 patients undergoing TBC treatment at Emergencia Grau Hospital from January to August 2021. The sample, obtained through a simple probabilistic sampling method, is 170 patients. Data will be collected using the survey technique. Accordingly, the research instruments consist of two questionnaires: the Therapeutic Adherence Scale (TAS) and the Questionnaire on Factors Associated with Therapeutic Adherence.
Acceso abierto
Adherencia al tratamiento antidiabético en pacientes hospitalizados en el Centro de Atención y Aislamiento Temporal COVID-19 Villa Panamericana, Lima – 2022
(Universidad Privada Norbert Wiener, 2022-11-25) Huaman Benites, Miguel Angel; Paulino Ortega, Gisela Adelaida; Caldas Herrera, Emma
Pharmacotherapeutic adherence is a discipline that patients must follow as guided by the prescriber to promote recovery or improvement and prevent complications in the body's functionality. Objective: To evaluate adherence to antidiabetic treatment in hospitalized patients at the COVID-19 Temporary Care and Isolation Center, Villa Panamericana, Lima, 2022. Method: The study was conducted using a deductive method with a quantitative, non-experimental, and cross-sectional approach. The study involved 217 hospitalized patients who met the inclusion and exclusion criteria. To measure pharmacotherapeutic adherence, the Morisky Medication Adherence Scale (MMAS-8) was used, validated by expert judgment, considering the following dimensions: sociodemographic data, clinical data, and therapeutic regimen. Microsoft Excel and SPSS v25 statistical software were used to analyze the results. Results: Among the 217 patients surveyed, 82% did not adhere to their pharmacological treatment. Of these, 82.1% were women, and 85.6% were over 60 years old. Additionally, 92.5% had only primary education, and 86.8% were from rural areas—all these groups were non-adherent to treatment. Regarding clinical data, 92.5% of patients were obese, 86.1% had fasting hyperglycemia, and 85.5% were receiving oral hypoglycemics and insulin. Among the treatment types, 86.7% were on dual therapy. Conclusion: In the studied population, 82% did not follow medical prescriptions, increasing the risk of complications and comorbidities associated with their condition.
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Adherencia al tratamiento de diabetes mellitus tipo II en usuarios de la botica Inkafarma en Lince – Lima Metropolitana, 2023
(Universidad Privada Norbert Wiener, 2024-11-19) Cubas Maldonado, María Alondra; Sáenz Cotrina, María Luz; Ramos Jaco, Antonio Guillermo
Objective: Determine the relationship between the factors and adherence to the treatment of type II diabetes mellitus in users of the Inkafarma pharmacy in Lince, Metropolitan Lima 2023. Methodology: The present study has a quantitative, basic, correlational, non-experimental, cross-sectional approach; Survey technique and questionnaire instrument applied to 118 users. The data were analyzed with descriptive statistics presented in tables and figures. Results: They indicate the relationship between the associated factors and adherence to the treatment of type II diabetes mellitus in users of the Inkafarma pharmacy in Lince, Metropolitan Lima 2023, for the dimension "Socioeconomic factors" predominated (Sometimes) with a (58.05%) , for the dimension “Factors related to the provider: health system and team” it was found that it predominated (Sometimes) with (71.88%), for the dimension “Factors related to therapy” it was found that it predominated (Sometimes) with (51.0%), for the dimension “Factors related to the patient” it was found that (Almost always) predominated with (45.75%), finally it was evident that 34.8% demonstrated adherence to the treatment of diabetes mellitus type II, while 65.3% do not have such adherence. Conclusion: The relationship between the associated factors and adherence to the treatment of type II diabetes mellitus in users of the Inkafarma pharmacy in Lince, Metropolitan Lima, was highly significant, moderately positive (r= .647; p=0.000<0.05).
Acceso abierto
Adherencia al tratamiento farmacológico en pacientes con diabetes mellitus tipo 2 del Centro de Salud Pachacamac – Lima, 2022
(Universidad Privada Norbert Wiener, 2023-04-28) Osorio Polo, Dehisy Licet; Reyes Silverio, Stefani Perlita; Muñoz Jáuregui, Manuel Jesús
The objective of this research was to "Determine adherence to pharmacological treatment in patients with type 2 diabetes mellitus (DM2) at the Pachacamac Health Center - Lima, 2022." Methodology: Quantitative approach, observational cross-sectional design, descriptive level, and basic type. A sample of 100 patients diagnosed with DM2 undergoing pharmacological treatment at the Pachacamac Health Center was selected through non-probabilistic convenience sampling. Instrument: A validated questionnaire measuring pharmacological adherence, which demonstrated internal consistency (alpha=0.852). Results: Socioeconomic factors were significant for patient adherence to pharmacological treatment, with 56% classified as non-adherent. Patient-related factors were relevant to adherence, with 60% non-adherent. Health care system-related factors influenced adherence, with 55% adherent. Treatment-related factors were significant, with 79% non-adherent. Finally, disease-related factors were also relevant, with 97% of patients non-adherent to pharmacological treatment. Conclusion: 80% of DM2 patients at the Pachacamac Health Center are non-adherent to pharmacological treatment.
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Adherencia al tratamiento farmacológico recetado a pacientes pediátricos atendidos por consultorio externo del Instituto Nacional de Salud del Niño - San Borja. Lima 2021
(Universidad Privada Norbert Wiener, 2022-03-30) Ayala Ayala, Ruth Antonilla; Caldas Herrera, Emma
A study was conducted to determine and analyze adherence to prescribed pharmacological treatment for pediatric patients seen in the outpatient clinic of the National Institute of Child Health - San Borja. Lima 2021. It is a deductive study with a quantitative approach and a cross-sectional observational design, with a sample of 385 patients seen in the outpatient clinic of the National Institute of Child Health - San Borja between November 2021 and April 2022. A 13-question questionnaire was conducted, distributed in four dimensions, which measured the socioeconomic factor, treatment-related factor, sociodemographic factor, and medication adherence using the Morisky Green Levine Test. Of the results obtained, 17.14% were adherent to treatment and 82.86% did not present pharmacological adherence; the duration of treatment and female sex were determining factors in relation to adherence. Based on these results, we propose working toward the creation of a pharmaceutical care unit at the National Institute of Child Health in San Borja, to strengthen patient care and pharmacotherapeutic monitoring, thereby improving and contributing to patient adherence.
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Adherencia al tratamiento farmacoterapéutico en pacientes adultos con hipertensión arterial que acuden a una botica de San Juan de Lurigancho. Lima 2023
(Universidad Privada Norbert Wiener, 2024-02-22) Alegría Visitación, Iris Christina; Cárdenas Núñez, Aracelli del Pilar; Mendoza Barrios, Jesús Richard
In recent years, arterial hypertension has become a persistent problem that is significantly increasing among adults due to the lack of adherence to treatment. Objective: To evaluate adherence to pharmacotherapeutic treatment in adult patients with arterial hypertension who attend a pharmacy in San Juan de Lurigancho – Lima – Peru, 2023. Methodology: Deductive method, quantitative approach, applied type, observational design, cross-sectional, and descriptive level. A total of 300 patients were surveyed. Results: 69.7% of adult patients with arterial hypertension showed low adherence to their pharmacotherapeutic treatment, 19% showed medium adherence, and only 11.3% showed high adherence. Conclusion: It was determined that 69.7% of hypertensive adult patients attending a pharmacy in San Juan de Lurigancho present low adherence to their pharmacotherapeutic treatment. Furthermore, 77% of respondents in general reported that taking medication daily is considered uncomfortable when coping with the treatment plan.
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Adherencia farmacológica y su relación con la calidad de vida en pacientes con hipertensión arterial atendidos en la farmacia Novafarma del distrito de San Juan de Miraflores, Lima, 2023
(Universidad Privada Norbert Wiener, 2023-09-28) Purizaga Gómez, Víctor Renato; Susaya Alvarado, Angie Solange; Muñoz Jáuregui, Manuel Jesús
This research aimed to determine the relationship between pharmacological adherence and quality of life in patients with arterial hypertension treated at a Novafarma pharmacy in the district of San Juan de Miraflores, Lima, 2023. Methodology: Using a hypothetical-deductive method with a quantitative approach, the study was classified as basic research within a non-experimental framework. It followed a cross-sectional or transectional study design with a descriptive-correlational level. Two instruments were applied to 336 hypertensive patients treated at the aforementioned pharmacy. Results: A significant relationship was found between pharmacological adherence and quality of life (p=0.000; r=0.307). There was also a significant relationship between medication/food intake control and quality of life (p=0.000; r=0.154). Similarly, a significant relationship was observed between behavioral medical follow-up and quality of life (p=0.000; r=0.325). It was also demonstrated that there is a significant relationship between self-efficacy and quality of life (p=0.000; r=0.336). Furthermore, there is a significant relationship between pharmacological adherence and psychological health or mood (p=0.000; r=0.339), as well as physical health or somatic sensations (p=0.000; r=0.204). Conclusions: It was concluded that as pharmacological adherence increases, so does the quality of life in hypertensive patients included in the study.
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Adherencia terapéutica en el tratamiento antihipertensivo de los pacientes del Centro de Salud San Sebastián – Lima Metropolitana, 2022
(Universidad Privada Norbert Wiener, 2022-10-04) Zelaya Aguirre, Gladys Felicita; León Apac, Gabriel Enrique
The purpose of this thesis was to verify compliance with Good Prescribing Practices (GPP) and analyze Good Dispensing and Sales Practices in Botica Latina and Botica Líder in the San Martín de Porres and San Juan de Lurigancho districts, respectively, during the period of January–March 2019. A descriptive and prospective study was conducted, in which 270 medical prescriptions were evaluated and received from hospitals, clinics, solidarity hospitals, polyclinics, and private practices. 106 were from Botica Latina and 164 were from Botica Líder. To evaluate compliance with Good Prescribing Practices, the Manual of Good Prescribing Practices from the Ministry of Health and the General Directorate of Medicines, Supplies, and Drugs of Peru was used, as well as the respective manual for the analysis of good dispensing practices. It was found that 78.5% (212 prescriptions) omitted the patient's age, 76.3% (206 prescriptions) omitted the diagnosis, and 93% (251 prescriptions) omitted the issuance and expiration date. 65.2% (176 prescriptions) omitted the INN (International Nonproprietary Name), 43% (116 prescriptions) omitted the concentration, and 39.3% (106 prescriptions) omitted the dose frequency. Consequently, it is concluded that there is non-compliance with Good Prescribing Practices, which will limit dispensing in both districts.
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Adherencia terapéutica en pacientes con diabetes mellitus tipo 2 que acuden a la botica María Fe – distrito de Pachacamac – 2023
(Universidad Privada Norbert Wiener, 2024-05-05) Basilio Berrocal, Luz Rosmery; Muñoz Jáuregui, Manuel Jesús
This study aimed to assess therapeutic adherence in patients with type 2 diabetes mellitus attending Boticas María Fe in the district of Pachacámac in 2023. The methodology employed a quantitative approach with a deductive method, basic research type, non-experimental design, prospective study, cross-sectional cut, and descriptive scope. The sample consisted of 106 patients diagnosed with type 2 diabetes mellitus. The data collection instrument was a self-developed questionnaire, previously validated, employing Likert-type scales and demonstrating strong internal consistency (Cronbach’s alpha = 0.939). Data analysis was conducted using the SPSS statistical software. The main results showed that 50.94% of patients exhibited correct behavior, 49.06% consistently took their medication, 37.74% modified their lifestyle habits, and 58.49% reported receiving good care from healthcare professionals. In conclusion, patients diagnosed with type 2 diabetes mellitus who attend Boticas María Fe present high therapeutic adherence, with 50.94% evidencing adequate adherence.
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La adulteración y calidad desinfectante del alcohol expendido en oficinas farmacéuticas y otros establecimientos comerciales, Lima – Cercado, setiembre 2020
(Universidad Privada Norbert Wiener, 2022-05-19) Vargas Espinal, Maribel Juvenalda; Laureano Peña, Haydee Sonia; Llahuilla Quea, José Antonio
The methodology used consisted of a random probabilistic sampling of 32 samples of 96° ethyl alcohols in 1 L bottles sold in pharmaceutical offices (sample B: 15 samples from drugstores and pharmacies) and other commercial establishments (sample A: 17 samples from small shops, shopping centers, and street vendors). Methanol was identified using the chromotropic acid reaction method. A sensory evaluation was conducted according to Peruvian Technical Standard 211.007:2014. The determination of physicochemical parameters (pH, alcoholic strength, and density) was performed according to the United States Pharmacopeia and Peruvian Technical Standard 319.229:2014. Disinfectant effectiveness was determined in accordance with the UNE-EN 1040 method for chemical antiseptics and disinfectants. The results identified positive methanol results in 13.3% of the B samples and 11.76% of the A samples. The alcoholic strength showed results lower than 96°, with an average of 93 in the B samples and 79 in the A samples. Additionally, the disinfectant effectiveness in the sample with the lowest alcoholic strength for group B showed a bactericidal activity greater than 99.99% at 30 seconds of contact against the microorganisms S. aureus and P. aeruginosa, while for group A, no bactericidal activity was observed.

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Examinando Farmacia y Bioquímica por Línea de Investigación "Salud y Bienestar"