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Publicación Acceso abierto 3D Bitemark Analysis in Forensic Odontology Utilizing a Smartphone Camera and Open-Source Monoscopic Photogrammetry Surface Scanning(Association of Support to Oral Health Research (APESB), 2023-01) Kurniawan, Arofi; Chusid, An’nisaa; Utomo, Haryono; Istiqomah Marini, Maria; Novia Rizky, Rizky; Widayati Prakoeswa, Beshlina Fitri; Hamdani, Janice; Salazar-Gamarra, Rodrigo; Lauria Dib, Luciano; Alias, Aspalilah; Putera Mohd Yusof, Mohd. Yusmiaidil; Marya, Anand“Bitemark analysis is a challenging procedure in the field of criminal case investigation. The unique characteristics of dentition are used to find the best match between the existing patterned injury and the suspected perpetrator in bitemark identification. Bitemark analysis accuracy can be influenced by various factors, including biting pressure, tooth morphology, skin elasticity, dental cast duplication, timing, and image quality. This review article discusses the potential of a smartphone camera as an alternative method for 3D bitemark analysis. Bitemark evidence on human skin and food should be immediately recorded or duplicated to retrieve long-lasting proof, allowing for a sufficient examination period. Various studies utilizing twodimensional (2D) and three-dimensional (3D) technologies have been developed to obtain an adequate bitemark analysis. 3D imaging technology provides accurate and precise analysis. However, the currently available method using an intraoral scanner (IOS) requires high-cost specialized equipment and a well-trained operator. The numerous advantages of monoscopic photogrammetry may lead to a novel method of 3D bitemark analysis in forensic odontology. Smartphone cameras and monoscopic photogrammetry methodology could lead to a novel method of 3D bitemark analysis with an efficient cost and readily available equipment.“Publicación Acceso abierto “5G Technology in the Digital Transformation of Healthcare, a Systematic Review“(MDPI, 2023-02-09) Cabanillas-Carbonell, Michael; Pérez-Martínez, Jorge; Yáñez, Jaime A.“The world is currently facing one of the biggest problems related to health and the quality of healthcare. According to the goals outlined by WHO in the blueprint for sustainable development (SDG3), one of its objectives is to achieve universal health coverage and ensure a healthy lifestyle. In this regard, it is important to monitor and track the impact of applications that help address this problem. This systematic review provides an analysis of the impact of the 5G network on the use of apps to improve healthcare. An analysis of 343 articles was performed, obtaining 66 relevant articles, the articles were categorized into research conducted with fiber optic backbone network as well as future research. The main medical applications were identified as: telesurgery, mobile ultrasound, biosensor technology, robotic surgery and connected ambulance. In addition, it is classified and answer questions such as the most used to improve medical care and health quality, 5G-based applications used in media to improve medical care and health quality, databases and programming languages in telemedicine are the most used in 5G-based applications, the functionality available for telemedicine based on the use of 5G-based applications.“Publicación Acceso abierto A cross-sectional study to assess the level of satisfaction with virtual education in Peruvian medical students(Frontiers Media S.A., 2022-10-05) Grados-Espinoza, Pamela; Zila-Velasque, J. Pierre; Soriano-Moreno, David R.; Regalado-Rodríguez, Kateriny Margot; Sosa-Nuñez, Frank; Barzola-Farfán, William; Gronerth, Jim; Guizado, Lucia; Mejia, Christian R.“Objectives: Education has totally changed in the context of the pandemic. Therefore, the objective of the present study was to evaluate the factors associated with the level of satisfaction with virtual education in Peruvian medical students during COVID-19. Methods: Analytical and cross-sectional study, based on an online survey of students nationwide. We use previously validated instruments to measure the level of satisfaction and stress (EPP-10-c) of students with virtual education. For the associated factors, adjusted prevalence ratios (PR) were estimated using Poisson regression. Results: Of the 1,878 students surveyed, the median age was 21 years, 57.8% (1,086) were women, 34.8% (654) had a high level of satisfaction with virtual education and 10.7% (202) presented high levels of stress. The factors associated with a low level of satisfaction were attending the fifth year of study, the partial and non-virtual adaptation of the university to virtual education, and a high level of stress. On the other hand, the factors associated with a high level of satisfaction were the education platform used and the study method used. Conclusion: Seven out of 10 students presented a low level of satisfaction with virtual education, 1 out of 10 presented a high level of stress. The factors associated with the low level of satisfaction were attending the fifth year of study, the non-virtual and partial adaptation of the university to virtual education, and the high level of stress.“Publicación Acceso abierto A Functional Assessment Tool to DistinguishControls From Alzheimer’s Disease in Lima,Peru(SAGE Publications Inc., 2022-06-03) Custodio, Nilton; Montesinos, Rosa; Chambergo-Michilot, Diego; Herrera-Perez, Eder; Pintado-Caipa, Maritza; Seminario, Wendy; Cuenca, José; Mesía, Laura; Failoc-Rojas, Virgilio E; Diaz, Monica MBackground:The Alzheimer’s Disease Cooperative Study-Activities of Daily Living (ADCS-ADL) scale is a versatile functionalassessment tool for patients with Alzheimer’s disease (AD). We evaluated its performance in controls, Peruvians with MCI orAD.Methods:A cross-sectional study of older adults attending a neurology institute in Lima (Peru) with mild cognitive impairment(MCI),ADor cognitively healthy. Test-retest reliability (intraclass correlation coefficient, ICC; internal consistency, Cronbach’salpha) and validity were assessed.Results:We enrolled 276 individuals (AD: 113, MCI: 68, controls: 95) with no age, sex, educational level, and depressivesymptom differences. Reliability was ideal (ICC: .996), and Cronbach’s alpha was adequate (.937). The ADCS-ADL could notdifferentiate MCI from controls but did differentiateADseverity. The ADCS-ADL correlated highly with nearly all tools.Conclusions:The ADCS-ADL scale is reliable in a population withADin Lima, Peru. Future work may validate a tool forPeruvians with lower educational levels.Publicación Acceso abierto A rare case of autoimmune dysglycemia syndrome associated with systemic lupus erythematosus and dermatomyositis(Modestum LTD, 2023-04-09) Paz-Ibarra, José; Concepción-Zavaleta, Marcio; Quiroz-Aldave, Juan Eduardo; Kcomt Lam, Mikaela; Huauya, Edwars Gilvonio; Sueldo Espinoza, Diego; Gago Cajacuri, George“Autoimmune dysglycemia syndrome (ADS) is a rare condition that presents as episodes of hypoglycemia as well as hyperglycemia and is classified as insulin autoimmune syndrome (IAS) and type B insulin resistance (TBIR). Autoimmunity plays a key role in the pathogenesis ofthis disorder, as evidenced by the presence of autoantibodies against endogenous insulin or the insulin receptor, and by its association with rheumatologic disorders. Treatment usually includes glycemic control and immunomodulatory agents. We report a case of a 31-year-old woman who was admitted for severe hypoglycemia. Further workup revealed underlying systemic lupus erythematosus (SLE) with renal involvement. During hospitalization, she continued to experience episodes of fasting hypoglycemia, as well as episodes of postprandial hyperglycemia. Hypoglycemia associated with a high serum insulin concentration and positive anti-insulin antibodies were consistent with IAS. Likewise, hyperglycemia and hypoglycemia in association with weight loss, acanthosis nigricans, polycystic ovarian syndrome, and normotriglyceridemia strongly suggested TBIR, although testing for antibodies against the insulin receptor was not available in Peru. Immunosuppressive therapy and metformin were indicated, resulting in remission of SLE and ADS. Years later, the patient exhibited features of dermatomyositis, such as Raynaud’s phenomenon, muscular weakness, heliotrope exanthema, and elevated muscle enzymes. Once again, the patient received immunosuppressive therapy. ADS is an infrequent cause of hypoglycemia, and the coexistence of its two pathophysiological mechanisms in a patient with SLE and subsequent development of dermatomyositis is even more rare. Our case is the first one reported describing this association.“Publicación Acceso abierto “A Systematic Review of Earned Value Management Methods for Monitoring and Control of Project Schedule Performance: An AHP Approach “(MDPI, 2022-11-17) Mayo-Alvarez, Luis; Alvarez-Risco, Aldo; Del-Aguila-Arcentales, Shyla; Sekar, M. Chandra; Yáñez, Jaime A.“: Successful project management depends on ensuring the project’s objectives. Within these objectives, technical success is associated with achieving the expectations of the project baseline. The baseline of the project is made up of the definition of the scope (WBS), time (schedule) and costs (S curve) of the project. Directly, the project is expected to be technically successful if it manages to deliver its full scope on schedule and without associated cost overruns. Baseline performance management is how project managers track and control the progress of deliverables, timelines and associated costs. In a traditional approach, for waterfall-type projects that use the critical path paradigm, the baseline performance management tool par excellence is earned value management (EVM). Earned value management, in practice, works well when project costs are monitored and controlled; however, applying this approach to measure the status of the schedule presents serious inconsistencies. Over the last several decades, different variations of the original earned value have been developed to overcome some of these inconsistencies when used to measure project schedule status. Within these variations, we have the critical path earned value; the work in progress earned value; the critical path earned value and the work in progress; the earned schedule; and the critical path earned schedule. Each of these proposals tries to address some weakness of the original earned value management applied to time monitoring and control, for example, considering critical tasks as a focus on monitoring the progress of the schedule, solving the problem of task recognition late finishers, reporting schedule variances in time units and measuring adherence to the project’s schedule (P factor). Due to the exposed situation, it is necessary to determine which alternative of the versions of the original earned value is the most appropriate for the management of the project schedule, considering that there are several evaluation criteria that must be considered. In the present research, a systematic review and comparison of EVM and its variations for measuring project baseline schedule performance are performed to determine the most suitable methods for monitoring and controlling the project baseline schedule. For this purpose, the analytic hierarchy process (AHP) is used, and five comparison criteria are considered: schedule variation focused on critical tasks, recognition and measurement of the delay of tasks that finish late, schedule variation in time units, measurement of schedule adherence (P factor) and software support and development. The result of the AHP performed for comparing the methods shows that the best method for monitoring and controlling the project baseline schedule is the critical path earned schedule because it behaves adequately in comparison with the other methods for the evaluated comparison categories.“Publicación Acceso abierto A systematic review of mental health in rural Andean populations in Latin America during the COVID-19 pandemic(Frontiers Media SA, 2023-08-17) Moya-Salazar, Jeel; Jaime-Quispe, Alexis; Cañari, Betsy; Moya-Espinoza, Jeel G.; Contreras-Pulache, Hans“Background: COVID-19 has been causing mental health problems around the world, with rural and indigenous peoples likely to be the most aected. This systematic review synthesizes and critically analyzes the existing literature on mental disorders in the rural Andean population in Latin America. Methods: A systematic review with narrative synthesis was carried out following the PRISMA guidelines. We searched nine databases (PubMed/MEDLINE, Scopus, EMBASE, ScienceDirect, Web of Science, Cochrane, Scielo, LILACS, and Latindex), five public prepublication servers (SocArXiv, medRxiv, bioRxiv, SportRXiv, and Preprints), ALICIA, and Google Scholar for articles that included the analysis of mental health problems using data collected from the rural Andean population in Latin America. These were eligible for inclusion. Articles that included NonLatin American populations (including European or African migrants) and studies conducted prior to the COVID-19 pandemic (since the declaration of national lockdown) were excluded. Results: A total of 23,761 articles were retrieved, 14 of which met the inclusion requirements. Most were cross-sectional (n = 12) and related to anxiety (n = 9), depression (n = 8), and stress (n = 5). The mental health analysis of 5,976 rural dwellers from four countries in Latin America also included gray literature studies (n = 7) that allowed the quantification of mental health problems in adults (n = 7) and adolescents/children (n = 4). Only one study was multinational, and the quality of publications varied. Despite the high frequency of anxiety, depression, and stress symptoms among rural Latin American populations during COVID-19, published research is very limited. This review found preliminary evidence that the frequency of anxiety (45%), depression (27.6%), and stress (33.1%) in the rural population was associated with pandemic restrictions across countries. Measures of other psychiatric problems, such as distress or suicidal ideation, cannot be estimated. Conclusion: Regional-wide studies investigating changes in the frequency of symptoms of mental health problems in the context of the COVID-19 pandemic are warranted to inform culturally adapted prevention strategies. This study is limited to a narrative synthesis and may be subject to publication bia“Publicación Acceso abierto Academic Directors Facing Internet Addictions, Learning and Health Promotion(Richtmann Publishing Ltd, 2023-03-05) De Jesus Garcia Varela, Guillermo; Llópiz Guerra, Karel; Requeiro Almeida, Reinaldo; Saavedra-Lopez, Miguel A.; Calle-Ramirez, Xiomara M.; Hernandez, Ronald M.; Morante Becerra, LydiaThe result that is presented is expressed from a bibliographic review of works published during the last two years 2020-2022 and, through which it was possible to verify the relationships that are established between the work of the Academic Directors, before the latent challenge and visible that is the crossroads of Internet addictions, by university students, increased in the stage already overcome of social isolation imposed by Covid 19 but, with emphasis on the achievement of learning at this high educational level, its risks and consequent decreases in the attacks that occur as a result of procrastination. All associated with the addictive phenomenon, in a projection of health promotion that the current, humanistic, modern and developing university should not give up in any way, being precisely in this direction an unavoidable pillar of social development, which lies precisely in the high professional qualification. of the new generations committed to a prosperous and sustainable social change.Publicación Acceso abierto Acceptability of yacon flakes (Smallanthus sonchifolia) for dietary use with inulin(Rynnye Lyan Resources, 2022-04-28) Velásquez-Gamarra, J.; Lozada-Urbano, M.“This study aimed to elaborate on yacon flakes and determine the proximal composition of fresh yacon and final flakes, made at different temperatures (120°C, 150°C and 180°C) for 20 mins. We measured the acceptability of the sensory attributes: taste, texture, odour and colour and the global acceptability at the laboratory level, using semi-trained panellists and an unstructured hedonic scale. The acceptability of the flakes was measured at different temperatures. Our results indicate that the flakes made at 180°C had the highest acceptance (87%), and the flakes made at 120°C had 80% of unacceptability. Our data were analysed according to the analysis of variance (ANOVA) and Tukey's test. We found significant differences between the averages of the taste scores (T0:7.1; T1:7.6; T2:6.7; T3:4.6), p<0.05; texture (T0:7.1; T1:7.2; T2:5.7; T3:4.5), p<0.05; and odour (T0:7.2; T1:7.6; T2:5.1; T3:3.3), p<0.05. The amount of fructooligosaccharides on a fresh basis was Ⱦ±SD (31.60±0.650) and on a dry basis (37.44±1DS). Microbiological analysis shows that the flakes are fit for human consumption. It is concluded that yacon flakes contain significant amounts of inulin, being a good substitute alternative for the preparation of snack-type dietetic products“Publicación Acceso abierto Actitudes del autocuidado de pacientes con tuberculosis en enfermeros peruanos luego de un brote hospitalario(Editorial Ciencias Medicas, 2023-06) Siesquen, Jessica J.; Moya-Salazar, Jeel; Ubidia-Incio, Roberto; Rojas-Zumaran, Víctor; Moya-Salazar, Belén; Contreras-Pulache, Hans“Introducción: La tuberculosis es una de las principales causas de morbimortalidad en todo el mundo. Las medidas de prevención son clave para evitar su propagación y el contagio entre profesionales de salud. Objetivo: Determinar las actitudes del autocuidado sobre la tuberculosis en el personal de enfermería luego de un brote infeccioso hospitalario. Métodos: Estudio transversal, en personal de enfermería (n= 94; personal técnico n= 44; 46,8 %). Se incluyó al personal de enfermería voluntario > 18 años, de ambos sexos, que trabaje en el Departamento de Emergencia. Se usó el cuestionario de 15 ítems de Valle (2017), para estimar los conocimientos y actitudes sobre el autocuidado, 3 dimensiones: prevención, diagnóstico y tratamiento de la tuberculosis. Resultados: El promedio de edad de los participantes fue de 44,7 ± 8,8 años, el 88,3 % mujeres y el tiempo promedio de trabajo fue 11,2 ± 7,8 años. Se hallaron diferencias entre los años de servicio, entre los técnicos (8,55 ± 7,94 años) y profesionales (13,48 ± 6,98 años) (p< 0,001). El 100 % presentaron actitudes de aceptación del autocuidado en todas las dimensiones. El 4,5 % y el 27,3 % de técnicos presentaron actitudes de indiferencia en la dimensión diagnóstico y tratamiento de tuberculosis (p= 0,001). Conclusiones: Existen actitudes favorables en el personal de enfermería sobre autocuidado de la tuberculosis luego de un brote en un hospital de Lima, aunque en técnicos de enfermería se reportan actitudes de indiferencia en el diagnóstico y tratamiento de tuberculosis.“Publicación Acceso abierto Acute Hepatic and Renal Toxicity Assessment of Euphorbia huanchahana (Klotzsch & Garcke) Boissier (Huachangana) in Holtzman Rats(MDPI, 2022-06-30) Villafuerte, Graciela; Ñañez, Daniel; Félix, Luis M.; Moya-Salazar, Marcia M.; Torres-Véliz, Ernesto R.; Ramos, Antonio G.; Contreras-Pulache, Hans; Moya-Salazar, Marcia M.Background:Euphorbia huachahana (Klotzch & Garcke) Boissier (Huachangana)(EhKGBh)has been used for over a century for medicinal purposes in the Peruvian population; however, itssafety and possible toxic effects of use have not been reported. The purpose of this study was todetermine the acute hepatic and renal toxicity of EhKGBh in Holtzman rats. Methods: Analyticaland experimental study. The population consisted of 52 rats of both sexes weighing between 300 and350 g divided into four groups: G1 and G2 EhKGBh groups (26 rats each) and two control groups(10 rats each). The experimental group was administered EhKGBh at a single dose of 2000 mg/kg P.O.to demonstrate toxicity during the 14-day follow-up. A daily assessment of alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin (TBIL), andconjugated bilirubin (CBIL) was performed. Results: Evaluation of the liver tissue showed mildchanges in inflammation, predominantly vascular, with small clots. Kidney tissue did not showinflammatory or necrotic changes. However, we showed differences in the weight of the rats betweenboth groups (p< 0.004) and significant increases in TBIL (0.98–1.07 mg/dL), CBIL (0.43–0.45 mg/dL),AST (126.4–141.8 U/L), and ALP (254–298 U/L) but not ALT (39.7–41.1 U/L) (p< 0.05). Conclusion:The single dose of EhKGBh extract at 2000 mg/kg has no toxicity, and there is no change in tissuetoxicity during the 14-day follow-up.Publicación Acceso abierto “Agricultural associations and fair trade in the Peruvian rainforest: a socioeconomic and ecological analysis“(LLC CPC Business Perspectives, 2023-03-16) Barro-Chale, Alexandra; Rivera-Castañeda, Patricia; Ramos-Cavero, Maria Jeanett; Cordova-Buiza, Franklin“Fair trade initiatives represent an essential support for the scarce opportunities that have arisen in the agricultural sector, as they cover various areas that contribute to increasing good trade practices. It is essential to highlight the contribution of fair trade in urban and rural areas, as it becomes a valuable incentive for differentiation. The main objective of this study was to determine how Fair Trade is applied in the socioeconomic and ecological sphere in an association of sustainable agricultural producers in the Peruvian jungle. This is quantitative research with a non-experimental crosssectional design. The survey technique was used, and a questionnaire was applied to 99 agricultural producers in the Amazon region of northern Peru, because it would help to analyze the new challenges of fair trade. In addition, data analysis and processing was carried out with Microsoft Office Excel and SPSS. The results show that 51% of the producers surveyed have been sensitized to adopt socially responsible actions aimed at strengthening sustainable development, social responsibility and good practices for fair trade in favor of the preservation of the resources of the Peruvian Amazon, as well as the socioeconomic development of farmers and the region itself. Forty-seven percent carry out social responsibility activities under the guidance of the Fairtrade organization, which has accompanied farmers to obtain Fairtrade certification. In addition, 59% of respondents say that they engage in healthy competition that generates trust among farmers. Fairtrade enables associated farmers to improve their ethical behavior and respect for their rights as well as those of the entire community“Publicación Acceso abierto ALFABETIZACIÓN EMOCIONAL EN CONTEXTOS VULNERABLES CON DIBUJOS DIGITALES(Global Knowledge Academics, 2022) HOLGUIN-ALVAREZ, JHON; CRUZ-MONTERO, JUANA; APAZA-QUISPE, JUAN; MERINO FLORES, IRENE; RUIZ- SALAZAR, JENNYThe objective sought to determine the effects on emotional literacy in the elaboration of digital drawings and traditional drawings in the cooperative and individual pedagogical format. 120 schoolchildren from vulnerable contexts participated. The data was collected by a scale based on Fury's proposals. Se advierten efectos de mejora en el cambio de laalfabetización emocional, y en sus componentes de expresividad y valencia. Improvement effects are noted in the change of emotionalliteracy, and in its components of expressiveness and valence. A higherlevel was detected in the change from negative to positive emotions in thedrawings of children who used tablets collaboratively, as opposed to thosewho did so individually.Publicación Acceso abierto “Alteraciones citogenéticas en pacientes con diagnóstico de infertilidad en Lima, Perú “(Sociedad Chilena de Obstetricia y Ginecologia, 2022-06-09) Moya-Salazar, Jeel; Vega-Vera, Rafael; Rojas-Zumaran, Víctor; Contreras-Pulache, Hans“Introducción: La infertilidad es una enfermedad multicausal y el componente genético representa uno de sus principales eventos. Si bien la distribución de la infertilidad puede variar entre poblaciones, las parejas de los países con bajos y medianos ingresos pueden verse más afectadas por la infertilidad, con una proporción de alteraciones citogenéticas aún no esclarecidas. Objetivo: Evaluar la frecuencia de alteraciones citogenéticas y su correlación con el número de abortos en pacientes peruanas con diagnóstico de infertilidad. Método: Se realizó un estudio de corte transversal en 400 pacientes de 18 a 60 años, de ambos sexos, con diagnóstico de infertilidad. Se registraron las características clínicas disponibles durante el examen genético y el análisis citogenético convencional fue con bandeo GTG en muestras de sangre periférica. El análisis de correlación se realizó con la prueba de Spearman. Resultados: Del total, 389 pacientes cumplieron los criterios de inclusión, y de estos, 169 (43,44%) tuvieron reportes de abortos (promedio: 2,25, rango: 1-7). Hallamos una correlación significativa ente el número de abortos y las alteraciones citogenéticas (p < 0,000). Reportamos 25/289 (6,43%) alteraciones cromosómicas, de las que 11/25 (44%) fueron heterocromatinas constitutivas y 6/25 (24%) fueron translocaciones reciprocas. Las alteraciones citogenéticas más frecuentes fueron 16qh+ y 9qh+ (ambas con un 16%), y afectaron a 17 (68%) varones. Conclusiones: Existe una moderada frecuencia de alteraciones citogenéticas en pacientes peruanos con diagnóstico de infertilidad, y las alteraciones más frecuentes fueron heterocromatina constitutivas. Además, evidenciamos una correlación significativa ente el número de abortos y las alteraciones citogenéticas.“Publicación Acceso abierto Alterations in the coagulation markers did not showdifferences with the severity of COVID‐19 in Peruvianpatients: A cross‐sectional single‐center study(John Wiley and Sons Inc, 2023-01-30) Moya‐Salaza, Jeel; Cóndor, Liliana Y.; Zuñiga, Nahomi; Jaime‐Quispe, Alexis; Cañari, Betsy; Contreras‐Pulache, HansBackground and Aims:COVID‐19 is a pandemic disease that can lead to alteredlung function, systemic inflammatory events, and altered coagulation. During severestages of the disease, changes in coagulation homeostasis increase, leading tothrombosis, and increased risk of death. In this cross‐sectional study, we aimedto assess coagulation markers by COVID‐19 severity in Peruvian adults.Methods:During the second wave of infections, we included 186 adults diagnosedwith COVID‐19 (mean age 53.3 ± 16.3 years). Patients were divided into mild,moderate, and severe stages of COVID‐19, and coagulation markers includedprothrombin time (PT), activated partial prothrombin time (aPTT), fibrinogen,D‐dimer, and platelet count.Results:Of the total, 120 (64.5%) were males and 39 (21%) were in the intensivecare unit. We determine 104 (55.9%), 43 (24.7%), and 36 (19.4%) patients in mild,moderate, and severe stages of COVID‐19, respectively. In the severe stage ofCOVID‐19, patients had an average concentration of PT, aPTT, fibrinogen,D‐dimer,and platelets of 13.2 ± 0.9 s, 28.9 ± 4.3 s, 679.4 ± 185.1 mg/dL, 1.9 ± 3.1 μg/mL, and272.8 ± 88.9 cel/10 mm,3respectively. We found no differences in the concentra-tion of each marker according to severity (p< 0.05). Patients with severe COVID‐19had altered the aPTT, fibrinogen,D‐dimer, and PT in 31 (57.4%), 48 (88.9%), 37(68.5%), and 15 (27.8%) cases, respectively.Conclusions:Our results showed that although there is an alteration in coagulationmarkers, mainly fibrinogen andD‐fiber, there are no differences in concentrationaccording to the severity of COVID‐19.Publicación Acceso abierto An Analysis of Global Trends from 1990 to 2022 of Microbial Fuel Cells: A Bibliometric Analysis(MDPI, 2022-02-16) Rojas-Flores, Segundo; Ramirez-Asis, Edwin; Delgado-Caramutti, Jorge; Nazario-Naveda, Renny; Gallozzo-Cardenas, Moisés; Diaz, Félix; Delfin-Narcizo, DanielMicrobial fuel cells have undergone several modifications since their creation, mainly due to the different substrates that can be used as fuel for the generation of electrical energy. In this research, a deep and updated analysis of the characteristics of the literature published in the Scopus database from 1990 to 30 December 2022 has been carried out, finding 7055 documents indexed. The most used keywords are microbial fuel cells, performance, and electricity generation. From 2011 to the present, 5289 article-type documents were published; the article entitled “Microbial Fuel Cells: Methodology and Technology” by Logan B. E. et al., 2006 from Pennsylvania State University, USA in the Environmental Science and Technology journal of the ACS publisher was the most cited (4496 citations). On the other hand, in recent years, Chinese universities have begun to produce and highlight a number of documents positioning in the top ten, with six universities having the greatest presence in publications and as the country with the highest number of published and indexed documents (2773) in Scopus. Research on microbial fuel cells tends to grow, with China as a leading country on the subject, written by the author Wang X. It is observed that the new cell research trends deal with the modification and fabrication of electrodes with nanomaterials in order to improve their power and reduce costs to show their viability on a larger scale.Publicación Acceso abierto An Ensemble-based Machine Learning Model for Investigating Children Interaction with Robots in Childhood Education(Innovative Information Science and Technology Research Group, 2023-05-30) Fuster-Guillén, Doris; Guadalupe Zevallos, Oscar Gustavo; Sánchez Tarrillo, Juan; Aguinaga Vasquez, Silvia Josefina; Saavedra-López, Miguel A.; Hernández, Ronald M.“Investing in children's well-being and supporting high-quality pre-school education is a significant component of its promotion (ECE). All children have the right to participate. ECE teachers' thoughts about children's participation were examined to see if they were linked to children's perceptions of their participation. On the other hand, current studies focus on a single categorization method with lower overall accuracy. The findings of this study provided the basis for the development of an ensemble machine learning (ML) approach for measuring the participation of children with learning disabilities in educational situations that were specifically developed for them. Visual and auditory data are collected and analyzed to determine whether or not the youngster is engaged during the robot-child interaction in this manner. It is proposed that an ensemble ML technique (Enhanced Deep Neural Network (EDNN), Modified Extreme Gradient Boost Classifier, and Logistic Regression) be used to judge whether or not a youngster is actively engaged in the learning process. Children's participation in ECE courses depends on both the quantitative and qualitative characteristics of the classroom, according to this research. “Publicación Acceso abierto “Análisis con Google Trends y Our World in Data sobre la salud mental mundial en el contexto de la pandemia por covid-19“(Asociacion Colombiana de Psiquiatria, 2023-04-04) Andía-Rodríguez, Iván; Ayala-Laurel, Valeria; Díaz-Carrillo, Jimmy; Llange-Sayan, Marjorie; Picón, Samanta; Reyes-Reyes, Eder; Armada, José; Mejía, Christian R.“Introducción: Durante la pandemia de la covid-19 los servicios de salud mental no pudieron darse abasto debido a la gran demanda, por lo cual, muchas personas optaron por buscar información por Internet que las pudiera ayudar a sobrellevar el proceso psicológico que estaban experimentando en ese momento. Objetivo: Caracterizar la tendencia mundial de búsqueda del término «psiquiatría» en el contexto de covid-19 mediante Google Trends y Our World in Data. Métodos: Estudio descriptivo-transversal sobre las tendencias mundiales de búsquedas de información sobre psiquiatría en el contexto de la covid-19 bajo los términos «psiquiatría», «depresión», «ansiedad», «estrés», «insomnio» y «suicidio» en la categoría de salud en el periodo del 2020-2021. Se generaron gráficos temporales. Resultados: El término «psiquiatría» se mantuvo con un volumen relativo de búsqueda elevado y constante (entre 60 y 90), con una búsqueda importante y paulatina en el mes de abril. El volumen relativo de búsquedas de «depresión», «ansiedad» y «estrés» se mantuvieron constantes con ciertas fluctuaciones no significativas a lo largo del periodo 2020-2021. El término «insomnio» tuvo una predominancia entre enero y junio del 2020, fue decayendo poco a poco desde abril y se mantuvo constante hasta octubre del 2021. Finalmente, el término «suicidio» obtuvo un VRB fluctuante entre 60 y 100 durante este periodo. Conclusiones: Durante el periodo de estudio los temas relacionados con la salud mental y la especialidad de psiquiatría se mantuvieron constantes, con algunas variaciones fluctuantes pero no llamativas.“Publicación Acceso abierto “Análisis de impacto presupuestal de la vacunación contra COVID-19 en América Latina“(Editorial Ciencias Medicas, 2022) Taborda, Alejandra; Murillo, Diego Alejandro; Moreno, Carolina; Taborda, Paula Andrea; Fuquen, Marcela; Díaz, Paula Andrea; Londoño, Darío“Objetivo. Estimar el impacto presupuestal de la vacunación contra COVID-19 en seis países de América Latina: Argentina, Brasil, Chile, Colombia, México y Perú, durante el periodo 2021-2022. Métodos. Se evaluaron las vacunas de Sinopharm (BBIBP-CorV), Janssen (JNJ-78436735), Instituto de Gamaleya (Gam-COVID-Vac), Sinovac (CoronaVac), CanSino (Convidecia), AstraZeneca (Vaxzevria), Moderna (mRNA-1273) y Pfizer (BNT162b2), según disponibilidad para cada país. Se adoptó la perspectiva del sistema de salud, de manera que solo se incluyeron costos médicos directos. El horizonte temporal se adoptó teniendo en cuenta los tiempos de implementación de cada plan de vacunación, excluyendo menores de 16 años y gestantes. Se incluyeron los siguientes costos: costo de la vacunación y aplicación, costos de la hospitalización general aislamiento, cuidado intermedio e intensivo. Se compararon dos escenarios de vacunación: 1) Población que desea vacunarse (según las encuestas nacionales) y 2) Población que debería vacunarse (total susceptible de vacunación). Los costos agregados para cada escenario de vacunación se compararon con el escenario de no vacunación. Adicionalmente, se realizaron análisis de sensibilidad determinísticos y probabilísticos. Resultados. Los diferentes esquemas de vacunación contra COVID-19 disponibles en América Latina generan ahorros potenciales que oscilan entre USD 100 y USD 1 500 millones de dólares por país para el período 2021-2022, asumiendo que se logra implementar en su totalidad el plan de vacunación previsto en cada país. Conclusiones. La vacunación contra COVID-19 es una estrategia que además de reducir la morbilidad y mortalidad para Latinoamérica, genera ahorros potenciales para los sistemas de salud en la región.“Publicación Acceso abierto ANALYSIS OF LEISURE TOURISM IN PERU DURING THE COVID-19 PANDEMIC(Vilnius Gediminas Technical University, 2022-06-20) Mauricio, Ingrid; Mejía, Christian R; Salinas, Omar; Solano, Sofia; Vicente-Ramos, WagnerThis study analyzes the economic impact caused by the COVID-19 pandemic on leisure tourism in Peru, in terms of tourist services such as means of transportation, accommodation, city tours and restaurants. The analysis is based on the application of a survey. The cross-sectional analytical study evaluated 2,443 potential tourists of legal age from the 25 regions of Peru who intended to engage in leisure tourism during the quarantine period. Likewise, potential tourists who intended to make a trip culminating the quarantine (in the remaining time of the year 2020) were evaluated. Based on the study of people who were going to carry out local leisure tourism until the end of 2020, the estimated losses in tour-ist services amounted to approximately $203 dollars millions (based on a budget less than or equal to $83.00, the amount that most respondents were willing to pay for tourist services). An increase in the demand for domestic leisure tourism is expected associated with the reduction in prices of each tourist service in order to reactivate this sector economically.