Examinando por Materia "Alzheimer Disease"

Mostrando 1 - 4 de 4

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Critical review: effect of the use of probiotics as a supplement in patients with Alzheimer's
(Universidad Privada Norbert Wiener, 2024-07-11) Cervera Alarcon, Romy Claude; Espinoza Rado, Erika Paola
Alzheimer's AD as a pathology is a degenerative alteration of the central nervous system, which determines a loss of knowledge and reduced cognitive function. Patients with Alzheimer's are at serious risk of developing protein and energy malnutrition, which is associated with increased morbidity and mortality. Some alterations can affect the nutritional status of patients with Alzheimer's, which includes loss of autonomy, disorientation, eating disorders, weight loss and frequent ambulatory activities, and this would lead to progression in the disease. The present review aims to collect information on the use of Probiotics as a supplement in patients diagnosed with Alzheimer's. The clinical question was: What is the effect of using Probiotics through supplements in patients with Alzheimer's? An evidence-based nutrition (NuBE) approach was used. After searching databases such as PUBMED, SCIELO, SCOPUS, SCIENCE DIRECT, 13 articles were found, of which 9 were selected to be evaluated by the CASPE critical reading tool, the selected research was the Randomized Clinical Trial RCT Effect of Probiotics Bifidobacterium Breva in Improving Cognitive Function and Preventing Brain Atrophy in Elderly Patients With Suspected Mild Cognitive Impairment: Results of a Randomized, Double-Blind Study of 24 weeks (PREADVISE) which has a level of evidence AI and Grade of Recommendation I. The critical comment; This study included tests for the timely detection of mild cognitive impairment (MCI) and dementia such as ADAS-jcog and MMSE, which had a positive correlation with respect to supplementation with B. breve MCC1274 in preventing the progression of brain atrophy. After 24 weeks of supplementation, it gives us a broad overview of the nutritional intervention, this research was supported by other results; observational and prospective studies that suggest that the use of Probiotics improves mild cognitive function and the incidence of AD; Likewise, these studies are based more on the benefits of the intestinal microbiota and its relationship with mild cognitive impairment (MCI) and dementia.
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Effectiveness of cognitive stimulation interventions in delaying the progression of senile dementia in elderly patients
(Universidad Privada Norbert Wiener, 2019-11-24) Rojas Polo, Jessica Gloria; Zegarra Claudio, Anie Betzave; Avila Vargas Machuca, Jeannette Giselle
Objective: Systematize the evidence on the effectiveness of cognitive stimulation intervention to delay the progression of senile dementia in older adult patients. Material and Methods: The type of research was quantitative, the study design was a systematic review, the population was 777 articles, and the sample was 10 scientific articles published and indexed in scientific databases, the instrument was a search based data: Pub Med, Cochrane, Scielo, Epistemonikos, to evaluate the articles the GRADE method was used which evaluated the quality of evidence and the strength of recommendation. Results: The 100% articles correspond to Brazil 20%, England 10%, Canada 10%, China 10%, Italy 10%, Spain 10%, Europe 10%, France 10% and Chile 10%. In relation to the designs and types of studies, 20% systematic review, 10% systematic review and meta-analysis, 50% randomized controlled trial, 10% quasi-experimental, 10% case-control group. Conclusion: The evidence found shows that 100% indicate the effectiveness of interventions such as daily tasks, interaction and integration, physical and intellectual social activities, orientation tasks, language, visual and motor coordination, leisure activities among others in stimulation. cognitive function to delay the progression of senile dementia in older adult patients, benefiting increased memory, better self-esteem and self-image.
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Effectiveness of non-pharmacological therapy in improving symptoms of dementia and quality of life in older adult patients
(Universidad Privada Norbert Wiener, 2018-12-16) Medrano Lanazca, Nelly Gladys; Pretell Aguilar, Rosa Maria
Material and Methods: The evidence found based on the design type shows that 90% belongs to Systematic Reviews, and 10% corresponds to a Systematic Review and Meta-analysis. In terms of quality, 100% is high. These articles were selected from the databases Epistemónikos, Cochrane, Scielo, PubMed, Lilacs, and Dialnet. Results: The systematic review of the 10 pieces of evidence found that 90% of the research articles demonstrate the effectiveness in reducing dementia symptoms and improving the quality of life in elderly patients. In 10% of the reviewed studies, there is an improvement in symptom reduction, but insufficient evidence to determine an improvement in the quality of life for elderly patients with dementia. All 10 articles show that the application of various person-centered interventions at the cognitive, psychosocial, physical exercises, music therapy, massage therapy, and reminiscence levels show favorable results in improving neuropsychiatric symptoms, as well as memory, attention, and communication. Conclusion: 9 out of 10 research articles conclude that Non-Pharmacological Therapies are effective in improving and reducing dementia symptoms in elderly patients, with better results found in cognitive stimulation, psychosocial interventions such as physical exercise, group activities, and music. Their application has also shown to positively influence improvements in the quality of life of elderly individuals. 1 out of 10 articles finds improvement in the reduction of dementia symptoms, but there is insufficient evidence to demonstrate a positive impact on the quality of life in elderly patients with dementia.
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Systematic Review: "Effectiveness of Home-Based Physical Exercise Interventions in People Aged 50 to 75 Years with Alzheimer’s, Cerebrovascular Disorder, and Parkinson’s"
(Universidad Privada Norbert Wiener, 1905-07-09) Barrientos Benavides, María del Carmen; Yangali Tarazona, Victoria Jazmin; Bravo Cucci, Sergio David
Objective: To verify the effectiveness of home-based physical exercise interventions for individuals aged 50 to 75 with Alzheimer’s disease, cerebrovascular disorder, and Parkinson’s disease. Materials and Method: A systematic search was performed in the Pubmed, EBSCOhost, and SciELO databases. The selection bias in individual studies was assessed, and methodological quality was analyzed according to the PEDro scale. Studies included: Ten controlled clinical trials were included, involving individuals with neurodegenerative diseases (Alzheimer’s, cerebrovascular disorder, and Parkinson’s disease) who received care from multidisciplinary teams, with interventions using home-based physical exercise. One article compared elderly patients with hip fractures and cerebrovascular disorders. Results: Home-based physical exercise is effective for Alzheimer's disease, cerebrovascular disorder, and Parkinson’s disease. The quality of the studies varied from 2-7/10 on the PEDro scale. Conclusions: Home-based rehabilitation with physical exercise interventions shows effectiveness in maintaining physical and mental activity in Alzheimer's patients. For cerebrovascular disorders, there is more evidence supporting the effectiveness of home exercise, with favorable motor outcomes. For Parkinson’s disease, home exercise interventions have shown improvements in motor function and quality of life, especially using tools like the Microsoft Kinect.