Examinando por Materia "Antiinflamatorios no Esteroideos"

Mostrando 1 - 9 de 9

Acceso abierto
Actividad analgésica y antiinflamatoria del extracto etanólico de la raíz de Taraxacum officinale Wigg “diente león” en ratones (Mus musculus)
(Universidad Privada Norbert Wiener, 2018-05-07) Castañeda Cuadros, Renzo Gerardo; Miranda Velarde, Anthony Boris; Chávez Flores, Juana Elvira
The objective of the study was to determine the analgesic and anti-inflammatory activity of the ethanolic extract from the root of Taraxacum officinale Wigg, "dandelion," in mice. The root was macerated for 7 days in 70% ethanol. Solubility and qualitative analyses were performed, and the extract was determined to be soluble in polar solvents and to contain flavonoids and alkaloids. To determine the analgesic activity, the 0.8% glacial acetic acid-induced abdominal writhing model was used on 49 Balbin/C53/CNPB strain mice. The groups were a negative control (distilled water), a positive control (0.8% acetic acid), the ethanolic extract at 25, 50, and 100 mg/kg, and comparative standards of paracetamol (300 mg/kg) and tramadol (40 mg/kg). To determine the anti-inflammatory effect, the subplantar edema method was used, with dexamethasone (4 mg/kg) and diclofenac (50 mg/kg) as standard drugs. The evaluation of the extract's analgesic activity showed an effective dose of 100 mg/kg with 69% writhing inhibition. The anti-inflammatory activity was effective at a dose of 25 mg/kg, with an inhibition percentage evolving from 56% to 99% over a six-hour period.
Acceso abierto
Automedicación con AINEs en usuarios con patologías osteomusculares que acuden a boticas Inkafarma Villasol – Los Olivos – Lima Metropolitana, 2021–2022
(Universidad Privada Norbert Wiener, 2022-10-05) Consuelo Cruz, Haydee Isandra; Orihuela Juica, Mery Aracelly; Justil Guerrero, Hugo Jesús
The objective of this research was to "Determine the relationship between self-medication with NSAIDs and musculoskeletal pathologies among users visiting Inkafarma Villasol Drugstores in Los Olivos, Metropolitan Lima, 2021–2022." Method: This was a hypothetical-deductive study, a basic type, with a quantitative approach. The sample consisted of 385 users. The instrument was a survey validated by subject matter experts. Data collection and processing were performed using the SPSS Version 25.0 statistical program and the Pearson's Chi-squared test. Result: The analysis of the relationship between self-medication with NSAIDs and musculoskeletal pathologies found a significant relationship (p value=0.000). For the relationship between anti-inflammatory preference and musculoskeletal pathologies, a significant relationship was found for diclofenac (p value=0.009), naproxen (p value=0.021), and meloxicam (p value=0.001). Conclusion: A significant relationship was determined to exist between self-medication with NSAIDs and musculoskeletal pathologies, with 50% self-medicating for an intermediate period until they achieved improvement.
Acceso abierto
Factores asociados a la automedicación y reacciones adversas de los antiinflamatorios no esteroideos en el asentamiento humano Villa Solidaridad, San Juan de Miraflores-2021
(Universidad Privada Norbert Wiener, 2022-08-25) Churampi Moreno, Ibeth Nora; Monroy Apaza, Delia Rosa; Alvarado Chávez, Britt
Our research aimed to determine the factors associated with self-medication and adverse reactions to non-steroidal anti-inflammatory drugs (NSAIDs) in the human settlement Villa Solidaridad, San Juan de Miraflores, 2021. Methodology: This was a quantitative, descriptive cross-sectional study with a sample of 336 residents, and the survey was used as the technique. Results: 98.8% of the surveyed population self-medicated. The reasons for this action included 65.1% citing lack of time, with 39.8% reporting headaches as the main symptom. Influences came from family and/or friends in 69.9% of cases. The frequency of self-medication was once a month for 62.3%. The age range was 47.0% between 26 and 40 years old, with 52.38% being female, 89.29% single, and 74.11% having higher education. Socioeconomically, 83.93% were employed, 55.95% had a medium income, and 36.31% had a low income. Regarding healthcare, 39.58% had Comprehensive Health Insurance (SIS), while 31.55% had no health insurance. A total of 63.9% were unaware of the risks of self-medication, 97.6% had no knowledge of the adverse effects of NSAID self-medication, and 100% of the surveyed population considered the information provided by the pharmacist about the medication they purchased important. Conclusion: Sociodemographic, economic, and cultural factors influence the high prevalence of self-medication, with the main reason being a lack of awareness about the adverse effects of NSAIDs.
Acceso abierto
Factores relacionados al nivel de conocimiento sobre efectos adversos de aines en compradores de la botica Susalud, Lima- 2024
(Universidad Privada Norbert Wiener, 2025-05-07) Aguirre Barrios, José Omar; Mendoza Arana, Pedro Jesus
The research work, entitled "Factors related to the level of knowledge about adverse effects of NSAIDs in buyers of the SuSalud pharmacy, Lima-2024", had the objective: To determine the factors related to the level of knowledge about adverse effects of NSAIDs in buyers of the SuSalud pharmacy, Lima-2024. Methodology: The study was quantitative, descriptive, and cross-sectional, with a sample of 185 purchasers selected through probability convenience sampling. A questionnaire validated by five experts with a Master's degree was used, consisting of 35 items that assessed sociocultural aspects, pharmaceutical marketing, multi-pathological conditions, and knowledge about NSAIDs. Data were analyzed in EPI INFO 7.2.6.0 using descriptive and inferential statistics, and information was processed using Cronbach's alpha. Results: A statistically significant relationship was found between knowledge level and age (≥40 years, p=0.0416), educational level (secondary or higher, p=0.0004), and income (≥1500, p=0.0473). In contrast, no significant relationship was found with sex (p=0.11), marital status (p=0.83), employment status (p=0.20), type of insurance (p=0.59), exposure to pharmaceutical marketing (p=0.30), or multiple pathologies (p=0.21). Conclusion: 81.62% of respondents had a low level of knowledge about the adverse effects of NSAIDs. The influence of sociocultural factors such as age, education, and income were confirmed, while pharmaceutical marketing and multiple pathologies did not show a significant relationship.
Acceso abierto
Influencia de la publicidad en la decisión de compra de productos farmacéuticos antiinflamatorios no esteroideos de venta libre (AINE) en consumidores en Lima Metropolitana durante el mes de setiembre de 2012
(Universidad Privada Norbert Wiener, 2013) Mayma Aguirre, Carlos Martín; Orellana Torres, Gabriela; Deluich Bobadilla, César Armando
Objective: To determine the influence of advertising on the purchase of over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) among consumers from different districts of Metropolitan Lima. Method: A total of 300 surveys with 11 questions were conducted among individuals who had at some point acquired over-the-counter NSAIDs and who were residents of Metropolitan Lima. Results: Seventy percent indicated that advertising influences their decision to purchase NSAIDs at the pharmacy; 12% consult a pharmacist when buying NSAIDs. Fifty-one percent are unaware that frequent use of NSAIDs causes harm. Furthermore, 45% relate frequent advertising of NSAIDs with greater confidence and safety when purchasing them. Conclusions: Advertising influences consumers when purchasing over-the-counter NSAIDs. Moreover, it was found that pharmacists are not consulted, that the adverse effects of frequent use are unknown, and that frequent advertising conveys trust and security to acquire over-the-counter NSAIDs.
Acceso abierto
Nivel de conocimiento sobre efectos adversos de AINE en trabajadores de salud de farmacias y boticas del distrito de San Martín de Porres Lima – Perú, 2022
(Universidad Privada Norbert Wiener, 2023-02-18) Tello Aguirre, Liliana; Yesquen Bernal, Joseph Anthony; Rojas Wisa, Oscar Favio
The objective of this study was to analyze the level of knowledge about the adverse effects of NSAIDs among healthcare workers in pharmacies and drugstores in the district of San Martín de Porres, Lima, Peru, 2022. An applied, observational, cross-sectional, and non-experimental study was conducted with 259 healthcare workers. Results: Regarding the level of knowledge about the adverse effects of NSAIDs based on daily frequency, it was "high" in 10.4%, "medium" in 24.3%, and "low" in 65.3%. In the Dose dimension, knowledge was "high" in 69.5%, "medium" in 24.7%, and "low" in 5.8%. Regarding Mode of Administration, knowledge was "high" in 69.9% and "low" in 30.1%. For Systemic Reactions, knowledge was "high" in 50.2%, "medium" in 38.2%, and "low" in 11.6%. Regarding Drug Interactions, knowledge was "high" in 18.5%, "medium" in 42.1%, and "low" in 39.4%. Finally, by gender, knowledge levels for males were "high" in 17.9%, "medium" in 64.3%, and "low" in 17.9%. For females, knowledge was "high" in 13.7%, "medium" in 72.6%, and "low" in 13.7%. Regarding education level, secondary education had a "medium" knowledge level at 100%, technical education had "high" at 27.8%, "medium" at 57%, and "low" at 15.2%. Higher education showed "high" at 10.7%, "medium" at 72.3%, and "low" at 17%. Conclusion: Healthcare workers demonstrated a "medium" level of knowledge about the adverse effects of NSAIDs, accounting for 69.8%.
Acceso abierto
Uso adecuado de antiinflamatorios no esteroideos en pacientes que acuden en la botica FARMASU en el distrito de San Juan de Lurigancho, Lima 2023
(Universidad Privada Norbert Wiener, 2023-11-21) Tarazona Moya, Marco Antonio; Ramos Jaco, Antonio Guillermo
The objective of this study is to analyze the proper use of nonsteroidal anti-inflammatory drugs (NSAIDs) among patients visiting the FARMASU pharmacy in the district of San Juan de Lurigancho, Lima, in 2023. The research methodology is non-experimental, deductive, quantitative, and applied. The population consisted of all patients who frequented the FARMASU pharmacy in San Juan de Lurigancho during March to May 2023. A questionnaire was administered to them after obtaining informed consent. Results indicate that 51% of patients purchase medications only when prescribed by healthcare professionals, 49.5% reported that healthcare professionals always explain how to use NSAIDs, and 63.5% stated they are attended by a pharmacist when purchasing the medication. Conclusion: It was determined that patients visiting the FARMASU pharmacy in San Juan de Lurigancho demonstrate proper use of NSAIDs. However, while a significant proportion of patients have a high level of knowledge and take NSAIDs with medical prescriptions, there remains a considerable number of patients who lack awareness of the rational use of NSAIDs.
Acceso abierto
El uso de AINES y su relación con la gastritis en los pacientes adultos del centro de atención primaria III El Agustino, Lima Metropolitana, enero a julio 2021
(Universidad Privada Norbert Wiener, 2022-04-27) Chavarría Palma, Silvia Marilú; Guadalupe Sifuentes de Posadas, Luz Fabiola
The objective of this study was to determine the relationship between the use of NSAIDs and gastritis in adult patients (40 to 85 years old). Methodology: The method employed was hypothetical-deductive, with a basic research type, a quantitative approach, a non-experimental design, and a correlational level. The sample consisted of 311 clinical records of patients from the general medicine area. For the information analysis, the two variables with their dimensions and indicators were considered. Results: Since the p-value is less than 0.05 (p = 0.026), the null hypothesis (Ho) was rejected and the alternative hypothesis (H1) was accepted at a 5% significance level. Conclusion: A significant relationship exists between the use of NSAIDs and gastritis in adult patients at CAP III El Agustino in Metropolitan Lima, during the January to July 2021 semester.
Acceso abierto
Uso racional de antiinflamatorios no esteroideos en pacientes que acuden a la cadena de boticas “Vida y Salud” en el distrito de San Martín de Porres. Lima 2023
(Universidad Privada Norbert Wiener, 2023-09-28) Ramírez Reyes, Lionel Charles; Sánchez Santa Cruz, Benito Abelino; Cano Pérez, Carlos Alfredo
The present study aims to analyze the rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in patients who visit the pharmacy chain "Vida y Salud" in the district of San Martín de Porres. Methodology: The research is non-experimental, deductive, quantitative, and applied. The population consisted of all patients who frequented the pharmacy chain "Vida y Salud" in the district of San Martín de Porres during April and May 2023. A questionnaire was administered to participants after obtaining their informed consent. Results: The findings indicate that 51% of patients purchase medications only when prescribed by healthcare professionals, and 49.5% report that healthcare professionals always explain how to use NSAIDs. Additionally, 63.5% stated that when purchasing the medication, they are attended to by a pharmacist. Conclusion: Patients visiting the pharmacy chain "Vida y Salud" in the district of San Martín de Porres demonstrate a rational use of NSAIDs. Furthermore, it is observed that the level of knowledge among patients is generally high, and they primarily take NSAIDs with a medical prescription. However, a significant number of patients still lack sufficient understanding of the rational use of NSAIDs.