Examinando por Materia "Benzodiazepinas"

Mostrando 1 - 9 de 9

Acceso abierto
Abordaje terapéutico con relación a trastorno del sueño en personas mayores de 50 años que acuden al mercado monumental Puente Piedra
(Universidad Privada Norbert Wiener, 2026-02-04) Oblitas Mejia, Yanina Yaneli; Jacinto Hervias, Pedro
El objetivo fue determinar la relación del abordaje terapéutico con los trastornos del sueño en personas mayores de 50 años que acuden al Mercado Monumental. Método. Fueron 172 personas que participaron en el estudio, la encuesta se realizó una sola vez sin manipular las variables, se realizó análisis de frecuencia, la hipótesis se analizó con rho de Spearman, el estudio fue correlacional y básico. Resultados. El 23,3% de las mujeres y 19,8% de los varones presentaron trastornos del sueño, en abordaje terapéutico para trastorno del sueño el 25% usaban diazepam y/o alprazolam, 22,7% usaban infusión de valeriana, 40,7% mejoró su descanso nocturno, 51,7% mantenían rutina regular para dormir y despertar, 39,0% evitaba cafeína antes de acostarse, el 75% percibió que el seguimiento profesional no mejoró su calidad del sueño. En síntomas de trastornos del sueño el 54,1% percibió que el sueño no fue reparador, 69,2% se sintió cansado al despertar, 80,8% dormían menos de 6 horas, 60,5% tuvo dificultad para mantener el sueño, 41,9% despertó varias veces durante la noche, 14,5% sintió somnolencia durante el día, 34,3% tuvo dificultad para concentrarse y 10,5% afectó su rendimiento diario. El 68% de trastorno del sueño fue severo. Se observó diferencia significativa alta (p=0,000; rho=0,847) entre el abordaje terapéutico y trastorno del sueño. Conclusión. La correlación entre el abordaje terapéutico con los trastornos del sueño en personas mayores de 50 años del Mercado Monumental fue significativa directa y alta.
Acceso abierto
Conocimientos y razones del consumo de benzodiacepinas en usuarios que acuden a los establecimientos farmacéuticos de San Martin de Porres, Lima enero-febrero 2025
(Universidad Privada Norbert Wiener, 2025-07-04) Menendez Figueroa, Edwin Cluber; Parreño Tipián, Juan Manuel
This study sought to determine the level of knowledge and reasons for benzodiazepine use among users who visit pharmacies in San Martin de Porres. The methodology used was basic, quantitative, descriptive, with a sample of 384 participants. The results showed that most of the respondents had intermediate or limited knowledge about their use, with 47.66% at the medium level and 42.44% at the low level, while only 9.90% had high knowledge. Likewise, it was observed that most users consume benzodiazepines for moderate reasons, representing 80.73%, followed by 11.20% at the low level and 8.07% at the high level, suggesting that, although consumption is present, most do so for moderate reasons and not extreme or minimal ones. Therefore, it was conclusively observed that the majority of participants stated that they took benzodiazepines mainly to relieve psychological or mental distress, leading to the conclusion that there is a clear need to improve education on the correct use and risks associated with these drugs.
Acceso abierto
Consumo de ansiolíticos y la dependencia ocasionada en los pobladores del asentamiento humano Huaycán en cadena de botica Inkafarma durante el año 2021
(Universidad Privada Norbert Wiener, 2021-11-30) Ollero Ibaceta, Jacqueline Nancy; Santos Serquén, Lourdes Fabiola; Ramos Jaco, Antonio Guillermo
The objective of this research was to determine the relationship between anxiolytic consumption and the resulting dependence among residents of the Huaycán Human Settlement at an Inkafarma drugstore chain in 2021. Methodology: The study was correlational, using a deductive method, a quantitative approach, a basic type, and a non-experimental, cross-sectional design. A validated questionnaire was used on a sample of 200 people. Result: All surveyed individuals consumed anxiolytics. The associated pathologies were anxiety disorders (46.5%), insomnia (19%), stress (18%), and depression and muscle pain (4%). The most consumed anxiolytics were benzodiazepines, specifically clonazepam (49%), alprazolam (39%), and diazepam (5%). The level of knowledge about the drugs was regular (82.5%), with 9% having little knowledge and 8.5% having no knowledge. Conclusion: It was determined that anxiolytic consumption is associated with pathologies like anxiety disorders and insomnia, with clonazepam and alprazolam being the most consumed benzodiazepines. The resulting dependence has a significant relationship with anxiolytic consumption.
Acceso abierto
Determinación de una técnica selectiva por cromatografía en capa fina para identificación de benzodiacepinas. Diciembre 2017
(Universidad Privada Norbert Wiener, 2018-12-05) Jiménez Martínez, Laura Mónica; Rodriguez Gariza, Yessica; Llahuilla Quea, José Antonio
The consumption of benzodiazepines is closely related to medico-legal aspects, as it is associated with criminal acts such as theft, crimes against sexual integrity, doping, and, from a clinical-legal perspective, dependence. Objective: To determine a selective technique by Thin-Layer Chromatography (TLC) for the identification of benzodiazepines. Method: Thin-layer chromatography was employed as a selective identification technique for benzodiazepines. Urine samples were collected from 26 healthy volunteers who had previously been administered benzodiazepines. The analysis was conducted in the toxicology laboratories of Norbert Wiener University and the National University of San Marcos (UNMSM). Results: Thin-layer chromatography tested positive for benzodiazepines and other substances (phenobarbital and phenytoin) in 80% of the urine samples analyzed. It is suggested that confirmatory techniques, such as gas chromatography–mass spectrometry (GC-MS), be used. Conclusion: Thin-layer chromatography was determined to be a highly sensitive technique, but not specific for benzodiazepines.
Acceso abierto
Factores asociados al consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de farmacia y bioquímica de la Universidad Norbert Wiener Lima, 2023
(Universidad Privada Norbert Wiener, 2025-03-03) Sanchez Ricaldi, Sadith Kimverli; Zea Yauce, Stephanie Lucero; Llahuilla Quea, José Antonio
La investigación tuvo por objetivo Determinar la relación entre los factores asociados y el consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de Farmacia y Bioquímica de la Universidad Norbert Wiener Lima, 2023. La metodología de estudio básico, de nivel correlacional, de corte trasversal y de diseño no experimental; la muestra fue de 255 alumnos de octavo y noveno ciclo de la facultad de Farmacia y Bioquímica, la técnica fue la encuesta y el instrumento el cuestionario; se realizó un análisis descriptivo, no se utilizaron inferencia estadística; interpretaremos la hipótesis directamente según la magnitud del coeficiente de asociación (V de Cramer). Con respecto a los resultados, se obtuvo que la situación laboral presentó una pequeña relación con el nivel de conocimiento (V de Cramer = 0,299) y la zona tiene relación pequeña con el consumo de benzodiacepinas (V de Cramer = 0,221); el tercio superior presentó una moderada correlación con el nivel de conocimiento (V de Cramer = 0,473) y las actividades extracurriculares presentó una correlación pequeña con el consumo de benzodiacepinas (V de Cramer = 0,109); los hábitos y actitudes negativas presentó una pequeña correlación con el nivel de conocimiento (V de Cramer =0,219) y los trastornos emocionales presentaron una correlación moderada con el consumo de benzodiacepinas (V de Cramer =0,436). Se concluye que, los factores asociados tienen relación moderada con el consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de Farmacia y Bioquímica de la Universidad Norbert Wiener Lima, 2023.
Acceso abierto
Factores asociados con relación al consumo de benzodiazepinas en adultos que acuden a la farmacia líder en el distrito de San Juan de Lurigancho. Lima 2023–2024
(Universidad Privada Norbert Wiener, 2024-07-10) Chavarria Chavez, Jhon Edward; Oyarce Alvarado, Elmer
The research aimed to determine the relationship between associated factors and benzodiazepine consumption in adults attending Farmacia Líder in the district of San Juan de Lurigancho, Lima, 2023–2024. A hypothetical–deductive methodology with a quantitative approach was applied, classified as basic research, with a non-experimental, cross-sectional, descriptive–correlational design. A validated instrument was administered to a sample of 270 adult benzodiazepine consumers. Results indicated that 57.4% of consumers were between 31 and 60 years old, with women representing the majority (65.0%). A relationship was observed between age and the clinical diagnosis leading to consumption, with 74.7% reporting use for anxiety and 28.3% for sleep disorders, both increasing with age. Furthermore, 32.9% consumed benzodiazepines due to family problems, 51.1% reported health issues, and 35.0% due to alcohol-related problems. In conclusion, there is a significant relationship between associated factors, particularly demographic and social dimensions, and benzodiazepine consumption among adults attending Farmacia Líder.
Acceso abierto
Identificación de errores de prescripción en recetas médicas del grupo de benzodiacepinas dispensados en botica “Gloria” San Borja, periodo mayo–diciembre 2015
(Universidad Privada Norbert Wiener, 2017-12-05) Duran Valerio, Verónica; Caldas Herrera, Emma
This research is a descriptive, observational, and prospective study. The guide from the Manual of Good Prescribing Practices, issued by the General Directorate of Medicines, Supplies, and Drugs (DIGEMID), was used as a reference. In the study, 1,470 (100%) medical prescriptions were reviewed, and 1,256 (85.44%) were found to have prescribing errors. The study determined that 102 (8.12%) prescriptions had errors in the omission of the prescriber's name, professional registration number, phone number, and address. Additionally, 6.45% were illegible, 9.24% had incomplete patient data, 9.63% did not use the International Nonproprietary Name (INN), 4.70% omitted the concentration, 10.91% lacked the pharmaceutical form, 13.37% lacked the dose and prescribed quantities, 18.15% did not indicate the route of administration, 3.74% lacked the professional doctor's signature and stamp, and 15.68% were missing the date of issue. In conclusion, when pharmacists observe that medical prescriptions do not comply with good prescribing practice standards, they must ask patients to have the doctor correct the errors and omissions, as the prescriptions cannot be filled if they are not correctly written.
Acceso abierto
Incidencia del uso de benzodiacepinas en casos de supuestos delitos contra la libertad sexual realizados en la Dirección de Criminalística de la Policía Nacional del Perú, año 2021
(Universidad Privada Norbert Wiener, 2023-02-03) Rivera León, Daniela Alicia; Rojas Vega, Angélica María; Rivas Altez, Walter
This research aimed to determine the incidence of benzodiazepine use in alleged sexual freedom crimes reported at the Criminalistics Directorate of the Peruvian National Police in 2021. The method employed was deductive, with a quantitative approach, basic type, and non-experimental, cross-sectional, and descriptive design. A total of 1,017 toxicological expert reports meeting the inclusion criteria were analyzed. The technique used was document analysis, and the data collection tool was a data collection sheet. Results: The findings showed the incidence of crimes against sexual freedom during 2021, with a high number of reported cases involving females, within the age range of 18 to 25 years, originating from police stations in downtown Lima. Intermediate-acting benzodiazepines were the most commonly used substances in cases of sexual assault. Conclusion: There is a high incidence of benzodiazepine use in alleged sexual freedom crimes reported at the Criminalistics Directorate of the Peruvian National Police in 2021.
Acceso abierto
Uso racional de las benzodiacepinas en pacientes que acuden a la farmacia de la Clínica San Martín en el distrito de San Juan de Lurigancho. Lima 2023
(Universidad Privada Norbert Wiener, 2023-11-20) Molina Cáceres, Jerson Joseph Ángel; Gaching Yeung, Francisco; Collanque Pinto, Jesús Daniel
The objective of this research was to determine the rational use of benzodiazepines in patients who attend the pharmacy of Clínica San Martín in the district of San Juan de Lurigancho. Methodology: A deductive study was conducted with a quantitative approach, applied type, non-experimental cross-sectional design, and descriptive level. A validated questionnaire was used, and its reliability was confirmed through Cronbach’s Alpha, obtaining a value of 0.847, which made the instrument reliable. The sample consisted of 122 patients. Results: Regarding the rational use of benzodiazepines, 55.7% sometimes made rational use of these medications, 29.5% always, and 14.8% never. About 50% reported that they were sometimes informed about possible interactions between benzodiazepines and other drugs. Alprazolam was the most consumed benzodiazepine (41%), followed by clonazepam (36.1%). Additionally, 58.2% indicated that they sometimes used an expired prescription, and 75.4% reported that the medication sometimes had no effect, leading them to double the indicated dose. Conclusion: It was concluded that among the surveyed patients attending the pharmacy of the clinic, 29.5% made rational use of benzodiazepines; however, it is concerning that 70.5% of this population made irrational use of these medications.