Examinando por Materia "Bioquímica"

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Actividad analgésica del extracto etanólico de las cáscaras de las pepas Persea Americana Mill "Palta Fuerte" en ratones
(Universidad Privada Norbert Wiener, 2017) Jiménez Colqui, Sofía Gaby; Chávez Flores, Juana Elvira
Persea americana Mill “Strong Avocado” is a plant species that is attributed with medicinal activities, such as antitussive and anti-flu; internal use in respiratory conditions (cold, cough and bronchitis), emmenagogue used in scanty and painful menstruation, Persea americana Mill “Strong Avocado” presents peripheral analgesic activity as well as anti-inflammatory. In the present work, the analgesic activity of the ethanolic extract of the shells of the seeds of Persea americana Mill “Strong Avocado” was verified in albino mice. With the method of Koster et al Modified of writhings induced by 0.6% glacial acetic acid used as a writhing stimulant, the concentrations evaluated were 50, 100 and 200 mg / kg, of extract of the shells of the seeds Persea americana Mill “Strong Avocado”, compared with Tramadol 40 mg / kg and acetylsalicylic acid 200 mg / kg. Obtaining a percentage of reduction in contortions with acetylsalicylic acid 200 mg/kg 88%, Tramadol 40 mg/kg 94%, Persea americana Mill 100 mg/kg 88%, Persea americana Mill 200 mg/kg 94%. The analgesic activity of the ethanolic extract of the shells of the seeds Persea americana Mill at 200 mg/kg was verified and a 94% reduction in contortions compared to Tramadol 40 mg/kg that have the same effect.
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Actividad antioxidante y efecto antibacteriano del aceite esencial de cáscaras de Citrus sinensis variedad Valencia Late
(Universidad Privada Norbert Wiener, 2021-06-09) Luque Lipa, Miguel; Marquez Vega, Rosalinda; Ramos Jaco, Antonio Guillermo
The present research work aimed to evaluate the antioxidant activity and antibacterial effect of the essential oil of Citrus sinensis peels variety Valencia Late. The extraction of the essential oil was carried out by steam distillation. The antibacterial effect was evaluated against the strains of Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 12228 following the agar diffusion method and the antioxidant activity was determined by the DPPH radical method (2,2-diphenyl-1-picrylhydrazyl). It is a quasi-experimental and quantitative research work. For the results in the antibacterial effect, a nonparametric Kruskal Wallis test was used. Regarding the antioxidant activity in the essential oil of Citrus sinensis peels variety Valencia Late, the IC50 (minimum concentration necessary to inhibit 50% of DPPH) was determined by a linear regression adjustment. The results were illustrated using bar charts and box plots. It was concluded that the essential oil of Citrus sinensis variety Valencia Late exhibits antibacterial effects against the two strains tested and antioxidant activity against the DPPH radical.
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Adherencia al tratamiento farmacológico recetado a pacientes pediátricos atendidos por consultorio externo del Instituto Nacional de Salud del Niño - San Borja. Lima 2021
(Universidad Privada Norbert Wiener, 2022-03-30) Ayala Ayala, Ruth Antonilla; Caldas Herrera, Emma
A study was conducted to determine and analyze adherence to prescribed pharmacological treatment for pediatric patients seen in the outpatient clinic of the National Institute of Child Health - San Borja. Lima 2021. It is a deductive study with a quantitative approach and a cross-sectional observational design, with a sample of 385 patients seen in the outpatient clinic of the National Institute of Child Health - San Borja between November 2021 and April 2022. A 13-question questionnaire was conducted, distributed in four dimensions, which measured the socioeconomic factor, treatment-related factor, sociodemographic factor, and medication adherence using the Morisky Green Levine Test. Of the results obtained, 17.14% were adherent to treatment and 82.86% did not present pharmacological adherence; the duration of treatment and female sex were determining factors in relation to adherence. Based on these results, we propose working toward the creation of a pharmaceutical care unit at the National Institute of Child Health in San Borja, to strengthen patient care and pharmacotherapeutic monitoring, thereby improving and contributing to patient adherence.
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Análisis proximal y grado de aceptabilidad del queque de alcachofa (Cynara cardunculus L.) en la Cooperativa Umamarca San Juan de Miraflores Lima Metropolitana 2024
(Universidad Privada Norbert Wiener, 2024-10-23) Chavez Rojas, Evana; Quiroz Sanchez, Rosario; Guadalupe Sifuentes de Posadas, Luz Fabiola
Through this field, the study aims to determine the correlation of the proximal analysis and degree of acceptability of the artichoke cake (Cynara cardunculus L.) in the Umamarca cooperative of San Juan de Miraflores, for this we carried out the analysis of the artichoke cake, to identify its percentage of moisture, ash, fat, total carbohydrates, crude fiber and protein; In addition to a 9-point hedonic or sensory test, in order to know the degree of acceptance, 87 panelists (29 for each type of sample) were surveyed, who tested the cake samples in different percentages of artichoke (Sample at 0 % “M01”, 50% sample “M02” and 80% sample “M03”). The methodology was applied to determine the percentage of humidity NTP 206.011 2018, ash NTP 206.012, fats by calculation, crude fiber AOAC 962.09 and proteins AOAC 935 39 (Association of Analytical Communities). In the case of total carbohydrates, calculation was applied and in the degree of acceptability the internal consistency method using Cronbach's alpha coefficient, the value obtained was Alpha=0,789. Results in the proximal analysis of samples M01, M02 and M03 have the percentages of ash (2,52 – 2,79 and 2,17), humidity (37,63 – 37,90 and 41,26) fat (9,32 – 9,04 and 11,94), carbohydrates (43,05 - 43,47 and 39,69), crude fiber (0,35 – 0,14 and 4,94) and protein (7,48 – 6,80 and 4,94) respectively. In conclusion, we can state that there is a relationship between ash, protein, total carbohydrates, crude fiber, moisture and fat with the variable degree of acceptability.
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Características de los eventos relacionados al uso de dispositivos médicos en el hospital Nacional Guillermo Almenara Irigoyen, Lima 2021
(Universidad Privada Norbert Wiener, 2022-03-30) Chuquilín Ramírez, Luz del Carmen; Caldas Herrera, Emma
To achieve health-related objectives in relation to medical care and improving the quality of life of patients, medical devices are considered an indispensable element in the prevention, diagnosis and treatment of pathologies. In this context, it is essential to take into account the risks that technology entails in the post-marketing of these products, since these devices can cause serious injuries or death to the patient if not addressed appropriately. (1) According to the WHO, in the United States, approximately one million "adverse events due to medical devices" are reported each year, which is worrying because they could be fatal. Its objective is to reduce the number of injuries, illnesses and deaths caused by medical devices, it established strategic links with health leaders worldwide to address the existing problem. (2) In addition, the WHO states that the accessibility and optimal use of medical devices is one of the concerns raised within the Millennium Development Goals. Due to the wide range of devices, problems related to quality, failure in labeling / manufacturing, inadequate modifications, poor assembly, incorrect use, erroneous selection of usage parameters, accidental spills, wrong connections, environmental factors, electromagnetic interference, loss of power supply, inappropriate technical specifications prior to purchase, inadequate storage, lack of training, lack of policy in hospitals, among others, are frequently found. (4) Several published articles show that the main causes of adverse events are: non-compliance with the regulations established in the context of technovigilance, lack of knowledge and inappropriate use of health technology. In the current context of the pandemic, there is greater concern because medical resources are scarce, which impacts the need to expedite interventions, reports, notifications and there may be greater characterization of these events, which represent a high impact on both economic and social aspects that affect security; constituting an adverse event that can be prevented. (5) (6). These findings warrant increased research and studies that demonstrate the application of technovigilance programs, which are extremely necessary to demonstrate compliance with current regulations regarding user training, quality, safety, performance and efficiency of products, and which in turn contribute to reducing the occurrence of adverse events. The Guillermo Almenara Irigoyen Hospital is a category III-2 health care institution, it has been serving insured personnel for more than 80 years, it is large and receives patients Referrals from Lima Centro, Lima Este, and Lima Norte, which is why the flow of patients treated is quite high. In this sense, the likelihood of various events related to medical devices is also high, which is why the decision was made to conduct the investigation at this institution.
Acceso abierto
Características frente a la automedicación responsable en pobladores del distrito de San Juan de Miraflores, setiembre 2018
(Universidad Privada Norbert Wiener, 2019-06-27) Puza Peralta, Graciela Alicia; Cuba Zuñiga, Carla Katiuska; Ramos Jaco, Antonio Guillermo
English: Objective: To know the characteristics, knowledge and attitudes towards responsible self-medication in residents of the District of San Juan de Miraflores September 2018. Methodology: descriptive, based on questions and data analysis. Cross-sectional: measures the prevalence of an exposure or result in a defined population and at a specific time. Prospective, is carried out with data obtained at a specific time. Non-experimental design, through a survey. The survey was prepared by the evaluation instrument, collection and data procedure technique. Results: Our research on the characteristics, knowledge and attitudes towards responsible self-medication of residents of the District of San Juan de Miraflores shows results in the surveyed population: predominance of adults with 61.66% (233), compared to young people with 22.2% (84) and older adults with 16.1% (61); the male gender 50.5% (191) compared to females 49.5% (187); with self-employment of 60.6% (229) and dependent workers with 39.4% (149); the higher education level with 25.9% (98), higher technical 25.7% (97), secondary 25.4% (96) and primary with 23.0% (87) users; the marital status showed a predominance of married with 24.1% (91), cohabiting 23.0% (87), divorced 21.7% (82), single 19.8% (75) and widowed 11.4% (43) as a sociodemographic study. Faced with the question of whether they consult the Pharmacist Chemist or the Pharmacy technician, it was (55.2%) while (52.6%) accepts advice from other people to self-medicate, (52.6%) states that advertising influences self-medication. Conclusions: There is a clear association between the characteristics, attitudes, and knowledge of the residents of San Juan de Miraflores regarding self-medication.
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Clima organizacional y satisfacción laboral del personal químico farmacéutico del departamento de farmacia en el Hospital Nacional Hipólito Unanue-Agustino 2021
(Universidad Privada Norbert Wiener, 2022-06-11) Pulido Janampa, Alina Rosa; Caldas Herrera, Emma
Methodology: The total sample comprised 30 professionals from the pharmacy department. The study was a cross-sectional, comparative, correlational study, in which the relationship between the variables was established. Statistical analysis was performed using the Chi-square test. Results: Low job satisfaction and low organizational climate represented 0.0%, low job satisfaction and medium organizational climate 8.3%, low job satisfaction and high organizational climate 0.0%. Medium job satisfaction and low organizational climate represented 100.0%, job satisfaction and medium organizational climate 79.2%, and medium job satisfaction and high organizational climate 66.7%. It is concluded that there is a significant relationship between organizational climate and job satisfaction among the chemical pharmaceutical staff of the pharmacy department at the Hipólito Unanue National Hospital.
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Concentración de mercurio y arsénico en Aulacomya atra Choro comercializado en los terminales pesqueros de Ancón, Ventanilla, Chorrillos y Villa María del Triunfo en enero del 2018
(Universidad Privada Norbert Wiener, 2020-02-13) Centurión Contreras, Marleni; Centurión Contreras, Luz Aurora; Lizano Gutiérrez, Jesús Víctor
The objective of this research was to determine the concentration of mercury and arsenic in samples of Aulacomya atra (choros), which were collected from four fishing terminals located in Lima, Peru. The research methodology was cross-sectional and descriptive. Two calibration curves for mercury and arsenic using standard solutions were developed to measure the concentration of heavy metals in bivalves, which were analyzed using cold vapor atomic absorption spectrophotometry with a hydride generator for mercury and flame atomic absorption spectrophotometry with a hydride generator for arsenic. All filter-feeding bivalves were collected from the fishing terminals of Ancón, Ventanilla, Chorrillos, and Villa María del Triunfo. The results of this investigation showed low mercury concentrations in the 20 samples analyzed, ranging from 0.03 to 0.25 ppm for Hg and 0.32 to 1.35 ppm for As. Compared with Peruvian standards, the data obtained showed levels of this metal below the maximum allowable limit (0.5 ppm) according to SANIPES. It was concluded that the concentrations of the heavy metals analyzed do not exceed the maximum permissible values.
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Conocimiento sobre antibióticos y resistencia bacteriana, luego de una intervención educativa, en los pacientes del Centro Materno Infantil López Silva - Villa el Salvador, periodo julio a septiembre 2019
(Universidad Privada Norbert Wiener, 2020-10-01) Vidal Tacunan, Andres Leoncio; Maucaille Alhuay, Bernardo Luciano; Caldas Herrera, Emma
Indiscriminate use is causing the emergence of bacteria that are resistant to previously effective antibiotics. How can the knowledge that patients can acquire about the correct use of antibiotics transmitted by healthcare personnel help prevent the emergence of resistant bacteria? Objective: To evaluate knowledge about antibiotics and bacterial resistance, after an educational intervention, in patients at the López Silva Maternal and Child Center - Villa el Salvador, period July to September 2019. Methodology: This work is a longitudinal and pre-experimental study, with a quantitative approach. The sample size was 268 patients who were treated at the López Silva Maternal and Child Center during the months of July to September 2019. Results: After the educational intervention, it shows positive results since 86.4% of the patients surveyed revealed a high level of knowledge and 8.6% reached medium knowledge, only 5% of the patients surveyed presented a low level of knowledge about antibiotics and bacterial resistance. Conclusion: Knowledge about antibiotics and bacterial resistance in patients at the López Silva Maternal Center increased, demonstrating that the educational intervention had a positive effect.
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Conocimiento teórico y manejo del control de calidad interno de bioquímica de los laboratorios clínicos de los establecimientos de salud del primer nivel de atención, Lima 2023
(Universidad Privada Norbert Wiener, 2023-12-13) Amésquita Reyes, Sissy Liseth; Hermoza Moquillaza, Rocío Victoria
Objective: Determine the relationship that exists between theoretical knowledge and the management of internal biochemistry quality controls in clinical laboratories of primary care health facilities. Materials and methods: It was a correlational, cross-sectional and nonexperimental research type work. The variables to be investigated were theoretical knowledge and quality control management in a population of 96 people who work in primary care health facilities. Two intruments were used, subjected to validity and reliability tests, where the Kuder Richadrson method was used since they are dichotomous and a value of 0.85 was obtained as a result for the theoretical knowledge survey and for the quality control management survey, a value of 0.85 was obtained a result of 0.90 indicating that its reliability is good. Results: The result was that 79.2% of the study sample, present an inadequate level of theorist knowledge, while about the management of control an inadequate level of 85.4% is observed. Conclusion: A significant, direct and moderate correlation was found between both variables, with a significance level lof pvalue=0.000 < 0.05 in the clinical laboratory staff of primary care health facilities.
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Consumo y costo de antimicrobianos antes y durante la pandemia COVID-19 en recetas médicas de pacientes hospitalizados no Covid-19 del Hospital Domingo Olavegoya Jauja. Junín 2021
(Universidad Privada Norbert Wiener, 2022-03-30) Aliaga Callupe, Rocío Rosario; Caldas Herrera, Emma
The research was titled: Consumption and cost of antimicrobials before and during the COVID 19 pandemic in medical prescriptions of non-COVID 19 hospitalized patients at the Domingo Olavegoya Jauja Hospital. Junín 2021. The general objective was to evaluate the consumption and cost of antimicrobials before and during the COVID 19 pandemic in medical prescriptions of non-COVID 19 hospitalized patients at the Domingo Olavegoya Jauja Hospital. The methodology is applied, descriptive level and non-experimental and longitudinal design, the data collection technique was observational. The sample consisted of records from January to December 2019 and from January to December 2020 of the consumption and cost of antimicrobials. The results verified that by 2020 the mean consumption of antimicrobials in medical prescriptions of non-COVID 19 hospitalized patients at the Domingo Olavegoya Jauja Hospital decreased by 34 and the mode by 135. The mean cost of antimicrobials in medical prescriptions of non-COVID 19 hospitalized patients at the Domingo Olavegoya Jauja Hospital decreased by 1,955 and the mode by 0. Concluding, that there is a significant difference between the consumption and cost of antimicrobials before and during the COVID 19 pandemic in medical prescriptions of non-COVID 19 hospitalized patients at the Domingo Olavegoya Jauja Hospital. Junín 2021. (p = 0.009 < 0.05).
Acceso abierto
Correlación entre el índice de masa corporal con el colesterol y los triglicéridos en alumnos ingresantes a una Universidad Estatal. Lima, 2015
(Universidad Privada Norbert Wiener, 2017) Meza Merino, Fernanda Veronica; Puse Adanaque, Juan Carlos; Parreño Tipián, Juan Manuel
A descriptive, correlational, prospective, cross-sectional, and non-experimental study was conducted to determine the correlation between Body Mass Index, cholesterol, and triglycerides in incoming students at a Lima State University in 2015. The population consisted of 100 young students from the following majors: Business Administration, Environmental Engineering, Electronic and Telecommunications Engineering, Mechanical Engineering, and Systems Engineering. 41% were female and 59% male, aged 18 to 25 years. Data were processed and analyzed using SPSS version 21. For the bivariate analysis, the study variables were correlated using Fisher's exact test. It was found that 50.0% had a normal BMI; 38.0% are overweight and 12.0% are obese. Regarding total cholesterol, 54.0% have normal levels, 27.0% are at moderate risk, and 19.0% have hypercholesterolemia. Regarding triglycerides, 63.0% have normal levels, 25.0% are at moderate risk, and 12.0% have hypertriglyceridemia. When correlating BMI with cholesterol, a statistically significant relationship was found (p = 0.037). Likewise, when correlating BMI with triglycerides (p = 0.046), however, when correlating triglyceride levels with cholesterol (p = 0.719), no statistically significant relationship was obtained. The study determined that although 50.0% have a normal BMI, there is a statistically significant correlation between BMI and cholesterol and triglycerides. Therefore, it is necessary to promote a better lifestyle among university students.
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Correlación entre hemoglobina glicosilada y glucosa en ayunas en pacientes diabéticos mayores de 30 años de la Clínica Internacional, Lima, 2023
(Universidad Privada Norbert Wiener, 2024-05-05) Rodríguez Flores, Rodolfo; Guadalupe Gómez, Haydee Ana
Esta investigación trabajó como objetivo “Determinar como la hemoglobina glicosilada se correlaciona con la glucosa en ayunas en pacientes diabético-mayores de 30 años de la Clínica Internacional, Lima 2023”. La investigación fue centrada por el método hipotético-deductivo, de enfoque cuantitativo, diseño no experimental, de tipo básico y con alcance correlacional observacional. La muestra estuvo conformada por 182 pacientes que acuden a la Clínica Internacional de Lima 2023. Se empleó como instrumento la Ficha Observacional de Monzón, siendo a su vez validada por el investigador a través del juicio de expertos. El estadístico empleado para el procesamiento de los datos fue el SPSS 25.0. Se obtuvieron como resultados la existencia de una correlación significativa en Pearson de valor 0.861, con una significancia de 0.000. Se concluye que la hemoglobina glicosilada se relaciona con la glucosa en ayunas en pacientes diabéticos mayores de 30 años, debido a que al elevar el nivel de la glucosa también se eleva la hemoglobina glicosilada.
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Cumplimiento de Buenas Prácticas de Oficina Farmacéutica en boticas que solicitan asesoría en una consultora de Lima Centro, 2021
(Universidad Privada Norbert Wiener, 2022-10-07) Quispe Fuentes, Glorinda; Lopez Alvarez, Renzo David; Aquino Comun, Mery
This research was developed to determine the level of compliance with Good Pharmaceutical Practices in pharmacies that request advice from a consulting firm in Lima Centro, 2021. Pharmaceutical regulation in Peru is increasingly demanding; Good Pharmaceutical Practices seek to improve the services provided by pharmacies and pharmacies so that a greater number of pharmacies know and comply with these current technical standards. The study methodology was deductive, quantitative in approach, non-experimental and cross-sectional in design, and an observation guide with 59 questions and 07 strategically chosen dimensions was used as an instrument. The results obtained were that, of the 96 pharmacies, 17.71% complied with the guidelines of Good Pharmaceutical Practices at a low level, 51.04% at a moderate level, and 31.25% at a high level. In conclusion, pharmacies with moderate and low levels could improve their results with more advice and training from the consulting firm, while 31.25% are already complying with the regulatory guidelines.
Acceso abierto
Cumplimiento de las buenas prácticas de dispensación de medicamentos en farmacias y boticas del distrito de la Victoria periodo junio 2018 - mayo 2019
(Universidad Privada Norbert Wiener, 2020-10-15) Escudero Escudero, Paola Victoria; Huanca Mamani, Gladys Liliana; Rodríguez Arizabal, Julio Cesar
Dispensing is characterized by a series of activities ranging from receiving a prescription to delivering the product. This research aimed to evaluate compliance with Good Dispensing Practices for medicines in pharmacies and drugstores in the district of La Victoria, Lima, Peru, from June 2018 to May 2019. The methodology was descriptive, with an observational, cross-sectional, and prospective design. The sample was obtained from 117 pharmaceutical offices registered with the General Directorate of Medicines, Supplies, and Drugs (DIGEMID). Two sales situations were established: one with a prescription and one without a prescription. The results indicated that 80.3% of the staff in charge of providing care at the establishment were pharmacy technicians, 23.9% respected medical prescriptions, 56.5% of the Pharmacists provided a guiding and educational attitude, 100% of the establishments provided care without a prescription, and the most commonly suggested pharmacological group was an NSAID with 29.9%. It was concluded that there is a high percentage of non-compliance with Good Dispensing Practices for medicines in pharmacies and drugstores, which can generate hidden symptoms, adverse reactions, and unnecessary expenses for the population.
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Cumplimiento de las buenas prácticas de dispensación y prescripción en el servicio de farmacia del hospital 2 de Mayo enero-marzo 2021
(Universidad Privada Norbert Wiener, 2021-08-06) Salvador Honorio, Ana Rosmeri; Ortiz De La Cruz, Celia Veronica; Caldas Herrera, Emma
The research aims to: Determine the relationship that exists between compliance with Good Dispensing and Prescribing Practices in the Pharmacy Service of the 2 de Mayo Hospital, January-March 2021. The study method was: descriptive, cross-sectional observational, with the basic analysis type, the sample consisted of 377 prescriptions, collected over three months in the Pharmacy Service of the 2 de Mayo Hospital, Lima - Peru. Using the GPP and BPD manual, in order to make the data collection sheets having the reference points the particularities of the prescriptions and in this way evaluate if there is a relationship between compliance with the GPD and GPP attended in the Pharmacy Service of the 2 de Mayo Hospital. The Conclusions with which the research was reached was that the relationship that exists between compliance with GPD and GPP was determined using Spearman's Rho correlation strength, accepting as an alternative hypothesis and having a correlation coefficient of 0.933 showing that it has a very high degree of positive relationship.
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Cumplimiento de las buenas prácticas de prescripción de recetas atendidas en la farmacia del consultorio externo del Hospital Nacional Dos de Mayo Cercado de Lima: agosto-diciembre, 2018
(Universidad Privada Norbert Wiener, 2019-10-11) Espinoza Flores, Moner Felix; Justil Guerrero, Hugo Jesús
Regarding the prescriber's data, it was observed that they comply with the 2 indicators: prescriber's signature and seal 100%, issue date 99.6%, and do not comply and 2 indicators: expiration date 98.7%, Information to the Pharmacist, 99.5%. Likewise, regarding the medication data, it was observed that they comply with the 9 indicators, international non-proprietary name 99.2%. National request for essential single medications, 88.6%, prescription for medication by correct concentration 98.3%, pharmaceutical form 98.2%, total prescribed amount 99%, prescription with medication with Dose 94.2%, route of administration 84.4%, Dose frequency 92.9%, duration of treatment 75.7%, Conclusions. It was determined that most of the indicators comply, while a minority of the indicators do not, according to the good prescribing practices standard for standardized single prescriptions, served in the outpatient clinic pharmacy.
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Cumplimiento de las buenas prácticas de prescripción en establecimientos de salud PS I-2 de la zona de Huaycán-Ate. periodo junio-octubre 2019
(Universidad Privada Norbert Wiener, 2020-11-05) Deudor Rojas, Doris Sorayda; Caldas Herrera, Emma
Good Prescribing Practices (GPP) are the compliance with the items required on a medical prescription. Objective: To evaluate compliance with Good Prescribing Practices in PS I-2 health facilities in the Huaycán-Ate area. Period: June–October 2019. Methodology: A descriptive, observational, cross-sectional, and retrospective study. The sample consisted of 369 medical prescriptions. Results: Medical prescriptions do not record data on disease diagnosis in 1.9% (7 prescriptions), patient age in 0.8% (3 prescriptions), route of administration in 48.8% (180 prescriptions), frequency of administration 17.9% (66 prescriptions), dose 16.3% (60 prescriptions), treatment time 16.0% (59 prescriptions), drug concentration 14.6% (54 prescriptions), pharmaceutical form 6.5% (24 prescriptions), quantity of medications 2.4% (9 prescriptions); only the patient's name, prescription date, name, signature and stamp of the prescriber are 100% compliant. Conclusions: The prescriptions evaluated in the PS I-2 health facilities in the Huaycán area show non-compliance in 69.6% (257 prescriptions) and compliance in 30.4% (112 prescriptions).
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Desarrollo y validación de una metodología analítica para la cuantificación de fexofenadina 30mg/5ml suspensión oral por cromatografía líquida de alta resolución (HPLC)
(Universidad Privada Norbert Wiener, 2021-08-05) Maravi Armas, Jessica; Grimaldo Medina, Elisabeth Lourdes; Segura Vílchez, Tito Magno
The Analytical Method used in a Finished Product today must maintain the highest quality parameters of the laboratories, controlling the quality and reliability, ensuring that the validation process must comply with current standards. Objective: Demonstrate that the analytical method developed for the quantification of Fexofenadine 30mg / 5mL Oral Suspension by High Performance Liquid Chromatography meets the established performance parameters. Methodology: This analytical test study for an analytical technique validation is of an applied, descriptive, quantitative type and of a longitudinal and prospective design. Results: It was verified that the verification of the evaluated parameters was in accordance with their results of System Suitability, Selectivity, Stability, Accuracy, System and Method Linearity, Intermediate Precision, Instrumental Repeatability, Method Repeatability and Robustness, meeting their acceptance criteria established for an Analytical Method Validation. Conclusion: That the analytical method for the quantification of Fexofenadine 30mg/5mL Oral Suspension by high performance liquid chromatography HPLC meets the statistical results required for validation, demonstrating reliability.
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Determinación de arsénico, cadmio y plomo en barras de chocolate adquiridas en el centro comercial Polvos Azules de Lima Metropolitana en el periodo enero-febrero 2016
(Universidad Privada Norbert Wiener, 2017) Velazque Leiva, Miguel Angel; Hernández Aguilar, Manuel Gregorio
The purpose of this thesis is to determine the concentrations of Arsenic, Cadmium and Lead in chocolate bars purchased at the Polvos Azules Shopping Center in Metropolitan Lima. A collection of chocolate brands sold at the Polvos Azules Shopping Center in Metropolitan Lima was carried out, having a total of 10 samples, the analyzes were performed using the atomic absorption spectrophotometry method by hydride generator for Arsenic and by graphite furnace for Cadmium and Lead. Arsenic concentrations ranged from 0.21 mg / kg to 0.47 mg / kg with an average of 0.30 mg / kg, Cadmium concentrations ranged from 0.21 mg / kg to 0.57 mg / kg with an average of 0.34 mg / kg and Lead concentrations ranged from 0.15 mg / kg to 0.28 mg / kg with an average of 0.20 mg / kg. It is concluded that 100% of the chocolate bar samples purchased at the Polvos Azules shopping center in Metropolitan Lima during the period January-February 2016 contained concentrations of arsenic, cadmium, and lead; and did not exceed the maximum permissible concentration established by the Codex Alimentarius for each of these.