Examinando por Materia "Glucose"

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Asociación del antígeno prostático específico con los niveles de glucosa sérica en adultos que asisten de un centro de salud, Lima 2024
(Universidad Privada Norbert Wiener, 2025-02-07) Espinoza Valverde, Josué; Cossio Villar, Mery Ann
El presente estudio tuvo como objetivo determinar de qué manera se asocia el antígeno prostático específico (PSA) con los niveles de glucosa sérica en adultos que asisten de un centro de salud, Lima 2024. Se llevó a cabo una investigación cuantitativa, aplicada, relacional y de diseño no experimental, que consideró una población censal de 150 pacientes varones, de los cuales se analizaron los registros clínicos mediante técnicas documentales. El análisis estadístico incluyó medidas descriptivas (media, mediana, desviación estándar) y pruebas inferenciales, como la prueba de Kruskal-Wallis y el ANOVA. Los resultados evidenciaron que el PSA no se asocia significativamente con los niveles de glucosa sérica en términos generales (KW= 2.218, p= 0.330) así como tampoco existe diferencia significativa con los niveles de glucosa (ANOVA F=1.109, p= 0.333). Sin embargo, se identificaron diferencias significativas en el grupo etario de 35-44 años (KW= 6.554, p= 0.038) y en el grupo con IMC de 25-29.9 (KW= 39.222, p<0.001). Por lo cual, se concluye que el PSA no se asocia con los niveles de glucosa sérica en la población general, pero sí existen interacciones significativas en subgrupos específicos. Estos hallazgos resaltan la importancia de considerar factores como el IMC y el grupo etario en el análisis clínico del PSA, con implicaciones para la detección temprana de alteraciones prostáticas y metabólicas.
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Correlation between glycosylated hemoglobin and fasting glucose in diabetic patients over 30 years of age from the International Clinic, Lima, 2023
(Universidad Privada Norbert Wiener, 2024-05-05) Rodríguez Flores, Rodolfo; Guadalupe Gómez, Haydee Ana
This study aimed to determine how glycated hemoglobin correlates with fasting glucose in diabetic patients over 30 years old at the Clínica Internacional in Lima, 2023. Results: A significant correlation was found (Pearson's r = 0.861, p < 0.000), indicating that as fasting glucose levels rise, glycated hemoglobin levels also increase.
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Correlation between the blood profile and glucemia in patients with type ii diabetes cared for in a hospital in Arequipa, period 2020 to 2023
(Universidad Privada Norbert Wiener, 2024-06-30) Xesspe Ancalle, Saúl Hílmer; Huamán Cárdenas, Victor Raul
The study, conducted at a hospital in Arequipa, analyzed the laboratory data of 97 patients with type II diabetes. Data were collected to determine the relationship between hematologic profiles and blood glucose levels. The Spearman correlation coefficient was used, with a P-value of 0.000 and a very strong positive correlation for the variables hemoglobin, hematocrit, total white blood cells, neutrophils, eosinophils, monocytes, lymphocytes, and glucose (+0.75 to +0.90), a high positive correlation for band cells and glucose (+0.51 to +0.75), and a moderate positive correlation for basophils and glucose (+0.11 to +0.50), indicating that most of the study elements—hemoglobin, hematocrit, total and percentage white blood cell count—are related to glucose levels.
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Degree of accuracy and precision level of the most used Glucometers in Metropolitan Lima, 2015
(Universidad Privada Norbert Wiener, 1905-07-07) Talaverano Llactas, Luis Hover; Sandoval Vegas, Miguel Hernán
The Glucotest is a device for measuring blood glucose levels using electrochemical methods or photometric reflectance, available in different brands, designs, and applications for monitoring and treating diabetes. The objective was to determine the accuracy and precision of the most commonly used Glucotests in Metropolitan Lima in 2015, through a quantitative, technological, prospective, cross-sectional, descriptive, and correlational study. Three brands of devices were studied: Prestige Easy, Onetouch Ultra Mini, and Accu-Chek Active. Results were compared with laboratory results under internal and external quality control. Accuracy (E%), precision (CV%), and correlation were assessed using Pearson’s r. Results showed that Prestige Easy had an E% of 12.12% and CV% ranging from 4.53% to 4.89%, outside the desired range. Onetouch Ultra Mini had an average E% of 9.1%, with acceptable CV% values of 1.50% and 1.58% in levels I and II, and a CV% of 2.68% in level III. Accu-Chek Active had an E% of 6.17%, with acceptable CV% values of 1.50% and 1.58%, and a CV% of 2.68% in level III. Correlation coefficients were: Prestige Easy 0.77, Onetouch Ultra Mini 0.90, and Accu-Chek Active 0.96. In conclusion, the Glucotest Accu-Chek showed better accuracy compared to Prestige Easy or Onetouch Ultra Mini, although only 30% of values were accurate. Only the Accu-Chek Glucotest showed adequate precision quality at all three glucose levels studied, while the Prestige Easy test had lower precision. In general, precision was better than accuracy across all devices, but none met the ideal limits.
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Desarrollo y validación de un test para la medición de glicemia mediante el análisis de imágenes con un smartphone – 2024
(Universidad Privada Norbert Wiener, 2024-09-27) Guzman Heredia, Luis Angel; Saldaña Orejón, Italo Moisés
Introducción: un teléfono inteligente confiere portabilidad, comodidad y ahorro. Atributos que tienen la posibilidad de extenderse hacia el uso de sistemas analíticos y en consecuencia, ayudar al usuario a medir analitos cuando llegue las circunstancias de no disponer de las herramientas necesarias para medirlo de la manera estandarizada, además de poder llevar y realizar el análisis en cualquier lugar. Objetivo: determinar si el análisis por imágenes realizado a través de un Smartphone es válido o verificable para la medición de glucosa sérica con respecto al método por espectrofotómetro. Material y métodos: se diseñó un estudio no experimental de corte longitudinal en la clínica Guadalupe durante el periodo octubre – febrero 2024. Se evaluaron concentraciones séricas en un rango de entre 30 y 500 mg/dL mediante el método por espectrofotómetro y también mediante el análisis por imágenes a través de un smartphone. Resultados: se evaluaron concentraciones decrecientes a partir de 500 mg/dL donde el método por captura de imágenes por smartphone presento una linealidad a partir de 50 mg/dL, con respecto a la veracidad se determina que no existe diferencias significativas entre ambos métodos, también se realizó el coeficiente de variación en concentraciones alta (455mg/dL), media (200mg/dL) y baja (35.64 mg/dL) infiriendo que existe una buena precisión en concentraciones medias y altas, con respecto al límite de detección, de determina que el método por imágenes tiene un límite menor que el método por espectrofotómetro. Conclusión: se concluye que el análisis por imágenes posee un buen performance en concentraciones de 50mg/dL hasta 500 mg/dL en relación al método por espectrofotómetro.
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Effect of Magnesium Intake on Blood Glucose Control in Type 2 Diabetes Patients
(Universidad Privada Norbert Wiener, 2018-02-12) Cisneros Osorio, Cecilia Amelia; Torres Lizarbe, Zenaida Paola; Benites Azabache, Juan Carlos
The objective was to assess the effect of magnesium intake on blood glucose levels in patients with type 2 diabetes. This study is descriptive in nature, and the systematic review was conducted following the guidelines proposed by PRISMA. A systematic review was carried out by analyzing eight databases of studies published in Spanish, English, and Portuguese between 2006 and 2015. Thirty original articles were found, of which five were selected for analysis according to the inclusion criteria. The review shows that magnesium plays an important role in blood glucose control and results in clinically significant improvement in type 2 diabetes mellitus patients. Serum magnesium levels decrease as glucose levels increase in patients with type 2 diabetes mellitus. After reviewing each of the selected studies, we can conclude that magnesium intake is effective in controlling blood glucose levels in patients with type 2 diabetes.
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Effect of resveratrol supplementation in patients with type 2 diabetes mellitus
(Universidad Privada Norbert Wiener, 2020-12-18) Diaz Costilla, Kelen Shirley; Espinoza Rado, Erika Paola
Diabetes mellitus type 2 is a chronic disease that will present multiple complications. The present secondary research titled as a critical review: Efficacy of resveratrol in patients with diabetes mellitus type 2, aimed to determine whether supplementation with resveratrol reduces glucose levels. . The clinical question: What is the effectiveness of resveratrol supplementation in patients diagnosed with type II diabetes mellitus? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, MEDLINE, SCIELO, SCIENCE DIRECT, finding 54 articles, 10 being selected that have been evaluated by the CASPE critical reading tool, finally selecting the Randomized Clinical Trial titled Supplementation with resveratrol decreases glucose in blood without changing circulating CD14+ CD16+ monocytes and inflammatory cytokines in patients with type 2 diabetes, which has a level of evidence I and Grade of Recommendation I, according to the expertise of the researcher. The critical comment allowed us to conclude that resveratrol supplementation has positive effects on glucose reduction.
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Effectiveness of group education vs. individual education to improve the quality of life of patients with Diabetes Mellitus
(Universidad Privada Norbert Wiener, 1905-07-09) Silva Valencia, Teresa Isabel; Wong Valerio, Miryam Luisa; Remuzgo Artezano, Anika
Objective: Determine the effectiveness of group health education compared to individual education in improving the quality of life of patients with Diabetes Mellitus. Material and method: Retrospective systematic bibliographic search and review. The search was restricted to articles with full text and with a time limit of 10 years, and was carried out in the databases PudMed, Index de Enfermería, Scielo, Evidentia, Cochrane during the month of February 2016. Results: They were chosen 10 articles obtaining the following data: the application of group education has a great impact on the level of knowledge about the disease, as demonstrated in 100% of the articles reviewed, improving adherence to the treatment (66.6%), raising self-care levels (83.3%), achieving behavioral changes in relation to diet and physical activity (50%), therefore controlling biochemical parameters such as glucose (83.3%), and physical such as weight and BMI (33.3%) also shows other indicators such as: no diabetic complications (16.6%) which translate into a decrease in emergency care due to hyper or hypo glycemia. Conclusions: In this bibliographic review, group education is highlighted as the most effective method for the transmission of important knowledge. It also shows us the impact it causes as a means for socialization and the exchange of experiences. Structured group education as a complement to individual education appears necessary and extremely important to improve the quality of life and metabolic control of people with diabetes.
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Effectiveness of icodextrin against glucose solutions in improving the quality and outcomes of peritoneal dialysis in diabetic patients with chronic kidney disease.
(Universidad Privada Norbert Wiener, 2021-12-12) Vigo Puican, Alvaro Manuel; Capuñay Huaraya, Diana; Pretell Aguliar, Rosa María
Results: 50% of these studies (5/10) demonstrated superiority of icodextrin over glucose solutions for the success and improvement of treatment in patients with diabetes undergoing peritoneal dialysis for chronic kidney disease, while 40% (4/10) indicated that further studies were needed to demonstrate absolute superiority of icodextrin over glucose solutions, and 10% of the articles (1/10) indicated superiority of glucose solutions over icodextrin solutions. Conclusion: Of the 10 studies, 5 resulted in demonstrating the superiority of icodextrin over glucose solutions, while 4 of them indicated a superiority of icodextrin but mentioned that further studies were needed to define the absolute superiority of this, and 1 article indicated the superiority of glucose solutions over icodextrin for patients with diabetes undergoing peritoneal dialysis for chronic kidney disease.
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Effectiveness of oral dextrose gel for the prevention of hypoglycemia in at-risk neonates
(Universidad Privada Norbert Wiener, 2018-07-08) Torres Peralta, Noelia Isabel; Cajacuri Gonzales, Rocio Pilar; Pérez Siguas, Rosa Eva
Objective: To analyze available evidence from studies on the effectiveness of oral dextrose gel for the prevention of hypoglycemia in at-risk neonates. Materials and Methods: The systematic review on the use of oral dextrose gel in the 10 scientific articles reviewed and found on the topic was sourced from the following databases: PubMed, Cochrane, Scielo, PLoS Medicine, The Lancet, Journal, Biomedicine. The articles include 2/10 from New Zealand, 2/10 from Australia, 5/10 from the United States, and 1/10 from England. The research design was mostly systematic reviews and experimental in nature. Results: Of the 10 articles reviewed, 9/10 indicate that the use of oral dextrose gel is effective in preventing hypoglycemia in at-risk neonates, preventing mother-infant separation, and supporting the continuation of breastfeeding. Only 1/10 indicates that the use of dextrose gel for hypoglycemia is still unclear. Conclusions: The evidence shows that the use of oral dextrose is effective in preventing hypoglycemia in at-risk neonates. The use of oral dextrose gel is a perfect example of successful population-based management and should be used as a first-line treatment for neonates with hypoglycemia, thus preventing admission to neonatal intensive care, supporting family bonding, and contributing to successful breastfeeding.
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Glucose and lipid profile according to body mass index in children from 6 to 12 years old at Surquillo Child Maternal Health Center, 2019
(Universidad Privada Norbert Wiener, 2019-11-12) Flores Flores, Luz Marisol; Sandoval Vegas, Miguel Hernán
Objective: To evaluate and compare serum glucose concentrations and lipid profiles according to BMI and sex in children aged 6 to 12 years at the Maternal and Child Health Center in Surquillo, 2019. Methodology: Retrospective, analytical, cross-sectional, and non-experimental design. The study included 50 children aged 6 to 12 who attended the child health campaign at the Maternal and Child Health Center in Surquillo. Results: No statistically significant differences were found for age and sex according to BMI (Chi-square, p > 0.05). Also, 70.0% of the study population had altered BMI, of which 36% were overweight and 34% were obese. The highest glucose level found was 102 mg/dl; the highest triglyceride level was 175 mg/dl, and the highest cholesterol level was 257 mg/dl. For HDL cholesterol, the lowest level found was 29.3 mg/dl, while for LDL cholesterol, the highest level was 186 mg/dl. Finally, the highest VLDL cholesterol level found was 35 mg/dl. Both altered parameters were observed in the overweight group. Glucose, cholesterol, and LDL cholesterol had higher means in girls; HDL cholesterol was lower in girls, and triglycerides and VLDL cholesterol levels were variable for both sexes. Conclusion: No statistically significant differences in glucose and lipid profile were found according to BMI and sex (ANOVA, p > 0.05).
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Influencia de la concentración de glucosa en el tiempo de formación de tubo germinativo para la identificación de candida albicans, en una institución privada, Ate Vitarte, Lima 2024
(Universidad Privada Norbert Wiener, 2024-09-25) Palomino Espinoza, Gladys Nancy; Merino Falcón, Ernesto Enrique; Borja Velezmoro, Gustavo Adolfo
OBJETIVO: Demostrar la influencia de la concentración de glucosa en el tiempo de formación del tubo germinativo para la identificación de Candida albicans en una institución privada Ate Vitarte, Lima 2024. MATERIALES Y MÉTODOS: Se incubaron 140 sueros de concentraciones (71mg/dl-500 mg/dl), con cepas de ATCC Candida albicans y se observaron las formaciones de tubo germinativo a los 30, 60, 90 y 120 minutos, asimismo el análisis estadístico fue realizado con el programa IBM SPSS Statics versión 29.0.2.0. RESULTADOS: Las concentraciones de glucosa de 71 – 125 mg/dl (12.86%), formaron tubos germinativos a los 120 minutos; 127- 200 mg/dl (18.57%), a los 90 minutos; 204 - 448 mg/dl (58.57%), a los 60 minutos y 450 - 500 mg/d (10%), a los 30 minutos, respectivamente. Además, en la prueba de hipótesis, se obtiene un p-valor <0,001 y un Rho= -0,889. Asimismo, al comparar las concentraciones de glucosa en los distintos tiempos (30, 60, 90 y 120 minutos) de formación de tubo germinativo se obtiene que los tiempos 30 y 60 minutos presentan una diferencia estadísticamente significativa con tres grupos de comparación (p corregido, Bonferroni =0,000), pero el tiempo de 30 minutos podría estar influenciada por el efecto árbol de cangrejo. CONCLUSIONES: Existe una correlación inversa y estadísticamente significativa entre las concentraciones de glucosa y tiempo de formación del tubo germinativo; asimismo las concentraciones de glucosa estadísticamente significativo para un menor tiempo de formación del tubo germinativo son de 204 - 448 mg/dl y la mejor concentración de glucosa para la formación de tubo germinativo es de 326.29 ± 71.24 mg/dl.
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Labile and Stable Fractions of Basal HbA1c and Their Relationship with Basal and Post-Oral Glucose Tolerance in Patients Attended at Suiza Lab, Lima, 2017
(Universidad Privada Norbert Wiener, 1905-07-09) Arrarte Castro, Corina Doris; Delgado Ortiz, Sara; Sandoval Vegas, Miguel Hernán
A selection of 1455 patients was made, for whom HbA1c, fasting glucose, and glucose tolerance tests were requested from July to September 2017. This study is quantitative, basic, retrospective, cross-sectional, exploratory, and the research design is non-interventional. The results were analyzed statistically using descriptive measures such as the mean, median, and standard deviation for HbA1c, LA1C, SA1C, fasting glucose, and glucose tolerance at 120 minutes by sex. No significant differences were found in the patients for HbA1c, LA1C, SA1C, fasting glucose, and T 120 min by sex. A Pearson correlation between variables showed a considerable positive correlation in LA1C and SA1C. A positive weak correlation was found for glucose at 60 minutes in LA1C and SA1C, and a weak correlation in LA1C and moderate correlation in SA1C at 120 minutes.
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Physical exercise as an effective intervention for lowering glycosylated hemoglobin in adult patients with type II diabetes mellitus.
(Universidad Privada Norbert Wiener, 2018-08-04) Meneses Li, Gloria Ysabel; Avila Vargas Machuca, Jeannette Giselle
Objective: To systematically analyze the available evidence from studies on physical exercise as an effective intervention for reducing glycosylated hemoglobin in adult patients with type II diabetes mellitus. Materials and Methods: A systematic review of 10 scientific articles on physical exercise as an effective intervention for reducing glycosylated hemoglobin in adult patients with type II diabetes mellitus was conducted. These articles were found in the following databases: Lilacs, Scielo, Medline, Pubmed, Dialnet, and Epistemonikos. All articles were analyzed using the GRADE scale to determine their strength and quality of evidence. Results: Of the 10 articles reviewed systematically, 100% (10/10) demonstrate that physical exercise reduces blood glycosylated hemoglobin levels, improving metabolic control and the quality of life of adult patients with type II diabetes mellitus. Conclusions: Of the 10 articles reviewed, all 10 articles provide evidence that physical exercise is an effective intervention for reducing glycosylated hemoglobin in adult patients with type II diabetes mellitus.
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Preparation of a blueberry drink and effect of its consumption on serum glucose
(Universidad Privada Norbert Wiener, 2021-05-12) Gamarra Espinoza, Gino Francesco; Espinoza Rado, Erika Paola
The blueberry is a berry native to North America. In Peru, it was reported that blueberry production grew at an average rate of 206% per year between 2012 and 2018. Studies mention the presence of large amounts of anthocyanins, which have important biological activities such as antioxidant, antimutagenic, and hypoglycemic effects. Blueberries also contain flavonoids, which play an essential role in protecting against oxidative damage. The phytochemical composition of blueberries changes depending on their ripening stage, which causes changes in the cell wall, resulting in softening of the fruit, which improves its taste but also makes it more vulnerable to physical and microbiological damage. Ripe blueberries have a very short post-harvest life. Due to the fruit's characteristics, a method is required to extend its shelf life. In South America, studies have shown that nine out of ten people consume sugary drinks daily, with an average intake of about 450 ml per day. In Peru, an annual per capita consumption of 100 liters was reported in 2015, with a trend to grow by about 3% each year. Given the trend of sugary drink consumption, the massive production of blueberries in our country, the premature deterioration of the fruit's surface, and the attributed phytochemical properties, this project aims to formulate a blueberry drink that will be pleasant to the public and evaluated for its effect on serum glucose, compared with other drinks on the market. It will be conducted in two phases: the first involves a sensory evaluation, and the second, a clinical trial related to its consumption.
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Prevalence of Impaired Fasting Glucose and Its Relationship with Basal Insulin Levels in Patients Aged 5 to 15 Years Attending a Polyclinic in Surco from January to June 2016
(Universidad Privada Norbert Wiener, 1905-07-09) Gil Saavedra, Margarita Patricia; Plasencia Vega, César Augusto
Objective: To determine the prevalence of altered fasting glucose and its relationship with basal insulin levels in patients aged 5 to 15 years attending a clinic in Surco from January to June 2016. Materials and Methods: Descriptive, cross-sectional, retrospective, quantitative study. The results of fasting glucose and insulin tests from 179 patients were obtained. The data collection instrument was the hospital system database, which was then entered into the Microsoft Office Excel 2010 program for statistical analysis. Variables: Two variables were studied: fasting glucose and basal insulin levels in patients aged 5 to 15 years. Results: The correlation coefficient between altered fasting glucose and insulin was -0.495. The prevalence of altered fasting glucose was 6.7%. The distribution of the population according to their altered fasting glucose levels and age group was as follows: 3 patients (1.7%) aged 5 to 8 years, 6 patients (3.3%) aged 9 to 12 years, and 3 patients (1.7%) aged 13 to 15 years. According to sex, the prevalence in females was 7 (3.9%) and in males was 5 (2.8%). Regarding the results of basal insulin, all patients had values within the reference range, with a wide data dispersion observed (coefficient of variation 13.9%). Conclusions: The prevalence of altered fasting glucose was 6.7%. No direct and statistically significant relationship was found with basal insulin levels (Pearson r: -0.495). It was observed that females had a higher number of patients with altered fasting glucose results, possibly due to age-related hormonal changes. A wide distribution of basal insulin values was observed. Recommendations: It is recommended to conduct further studies in Peru with children and adolescent populations to gather more data on basal insulin and compare it with other studies. Additionally, reference values for insulin in Peruvian children and adolescents should be studied to obtain data for our population.
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Revisión crítica: efecto de la suplementación con moringa oleífera en pacientes adultos con diabetes mellitus tipo 2
(Universidad Privada Norbert Wiener, 2025-03-05) Taipe Ruiz, Blanca Regina; Ponce Castillo, Melissa
Varios estudios han evidenciado que la aplicación de Moringa Oleífera (MO) disminuye la glucemia sin causar efectos secundarios tóxicos. El propósito de esta Revisión crítica titulada: Suplementación con Moringa oleífera y su impacto en la glucosa en pacientes adultos con Diabetes Mellitus tipo 2 (DMT2), fue descubrir cómo la suplementación con MO ayuda a reducir los niveles de glucosa. La interrogante clínica fue: ¿Cuál es el efecto de la suplementación con Moringa Oleífera en la glucosa de pacientes adultos con DM tipo 2? Se empleó el enfoque Nutrición Basada en Evidencia (NuBE). Se buscó información en PUBMED, MEDLINE, SCIELO, SCOPUS y SCIENCE DIRECT. Se identificaron 47 investigaciones clínicas, de las cuales 10 se evaluaron mediante el instrumento de lectura crítica CASPE. Luego, se eligió la Revisión Sistemática (RS) denominada: Beneficios de Moringa oleífera en personas con diabetes tipo 2, que muestra una evidencia BII además de un elevado nivel de recomendación, con relación a la experiencia del científico. El análisis consideró que la ingesta de MO puede potenciar el control del índice glucémico en pacientes con DMT2. No obstante, la información es de baja calidad.